Genome-wide assessment ofMycobacterium tuberculosisconditionally essential metabolic pathways

Autor: Baughn Ad, Minato Y, Harcombe Wr, Chacón Jm, Gohl Dm, Maruyama F, Thiede Jm

Better understanding of essential cellular functions in pathogenic bacteria is important for the development of more effective antimicrobial agents. We performed a comprehensive identification of essential genes inMycobacterium tuberculosis, the majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9f73334b308b091fce833a796312de
https://doi.org/10.1101/534289

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A trans -translation inhibitor is potentiated by zinc and kills Mycobacterium tuberculosis and non-tuberculous mycobacteria.

Autor: Varshney A; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712 USA.; These authors contributed equally., Jia Z; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455 USA.; These authors contributed equally., Howe MD; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455 USA., Keiler KC; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712 USA., Baughn AD; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455 USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 02. Date of Electronic Publication: 2024 Nov 02.

Unique genomic sequences in a novel Mycobacterium avium subsp. hominissuis lineage enable fine scale transmission route tracing during pig movement.

Autor: Komatsu T; Aichi Prefectural Tobu Livestock Hygiene Service Center, Toyohashi, Aichi, Japan., Ohya K; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.; Education and Research Center for Food Animal Health, Gifu University (GeFAH), Gifu, Japan., Ota A; Data Science Center, Division of Biological Science, Nara Institute of Science and Technology, Ikoma, Nara, Japan., Nishiuchi Y; Office of Academic Research and Industry-Government Collaboration, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan., Yano H; Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan., Matsuo K; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.; Kumamoto Prefectural Aso Public Health Center, Aso, Kumamoto, Japan., Odoi JO; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan., Suganuma S; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan., Sawai K; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.; Division of Transboundary Animal Disease Research, National Institute of Animal Health, National Agriculture Research Organization, Tsukuba, Ibaraki, Japan., Hasebe A; Toyama Prefectural Meat Inspection Center, Imizu, Toyama, Japan., Asai T; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.; Education and Research Center for Food Animal Health, Gifu University (GeFAH), Gifu, Japan., Yanai T; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan.; Hiwa Natural History Museum, Shobara, Hiroshima, Japan., Fukushi H; Faculty of Applied Biological Sciences, Gifu University, Gifu, Japan.; United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan., Wada T; Graduate School of Human Life and Ecology, Osaka Metropolitan University, Osaka, Japan., Yoshida S; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Osaka, Japan., Ito T; Laboratory of Proteome Research, Proteome Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Ibaraki, Osaka, Japan., Arikawa K; Department of Infectious Diseases, Kobe Institute of Health, Kobe, Hyogo, Japan., Kawai M; Graduate School of Human and Environmental Studies, Kyoto University, Kyoto, Japan., Ato M; Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan., Baughn AD; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, USA., Iwamoto T; Department of Infectious Diseases, Kobe Institute of Health, Kobe, Hyogo, Japan., Maruyama F; Office of Academic Research and Industry-Government Collaboration, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.; Project Research Center for Holobiome and Built Environment (CHOBE), Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.; Scientific and Technological Bioresource Nucleus, Universidad de La Frontera, Temuco, Chile.

Publikováno v: One health (Amsterdam, Netherlands) [One Health] 2023 May 10; Vol. 16, pp. 100559. Date of Electronic Publication: 2023 May 10 (Print Publication: 2023).

Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis.

Autor: Cole MS; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA., Howe MD; Department of Microbiology, Immunology, University of Minnesota Medical School, 689 23rd Ave SE, Minneapolis, Minnesota 55455, USA., Buonomo JA; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA., Sharma S; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA., Lamont EA; Department of Microbiology, Immunology, University of Minnesota Medical School, 689 23rd Ave SE, Minneapolis, Minnesota 55455, USA., Brody SI; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA., Mishra NK; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA.; Department of Biotechnology, Gandhi Institute of Technology and Management (GITAM) School of Science, Deemed to be University, Gandhi nagar, Rushikonda, Visakhapatnam-530045, Andhra Pradesh, India., Minato Y; Department of Microbiology, Immunology, University of Minnesota Medical School, 689 23rd Ave SE, Minneapolis, Minnesota 55455, USA.; Department of Microbiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192, Japan., Thiede JM; Department of Microbiology, Immunology, University of Minnesota Medical School, 689 23rd Ave SE, Minneapolis, Minnesota 55455, USA., Baughn AD; Department of Microbiology, Immunology, University of Minnesota Medical School, 689 23rd Ave SE, Minneapolis, Minnesota 55455, USA., Aldrich CC; Department of Medicinal Chemistry, University of Minnesota, 308 Harvard St SE, Minneapolis, Minnesota 55455, USA.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Sep 12; Vol. 28 (51), pp. e202200995. Date of Electronic Publication: 2022 Jul 27.