Dorsomedial striatal AMPA receptor antagonism increases alcohol binge drinking in selectively bred crossed high alcohol preferring mice.

Autor: Bauer MR; Indiana Alcohol Research Center and Department of Psychology, Indiana University Indianapolis, Indianapolis, Indiana, USA., McVey MM; Indiana Alcohol Research Center and Department of Psychology, Indiana University Indianapolis, Indianapolis, Indiana, USA., Zhang Y; Indiana Alcohol Research Center and Department of Psychology, Indiana University Indianapolis, Indianapolis, Indiana, USA., Boehm SL 2nd; Indiana Alcohol Research Center and Department of Psychology, Indiana University Indianapolis, Indianapolis, Indiana, USA.

Publikováno v: The European journal of neuroscience [Eur J Neurosci] 2024 Nov; Vol. 60 (9), pp. 6300-6311. Date of Electronic Publication: 2024 Oct 02.

mRNA Display Identifies Potent, Paralog-Selective Peptidic Ligands for ARID1B.

Autor: Cremosnik GS; Global Discovery Chemistry, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Mesrouze Y; Disease area Oncology, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Zueger P; Global Discovery Chemistry, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Furkert D; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Grandjean F; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Argoti D; Global Discovery Chemistry, Novartis Biomedical Research, Emeryville, California 94608, United States., Mermet-Meillon F; Disease area Oncology, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Bauer MR; Global Discovery Chemistry, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Brittain S; Discovery Sciences, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Rogemoser P; Discovery Sciences, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Yang W; Discovery Sciences, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Giovannoni J; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., McGregor L; Discovery Sciences, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Tang J; Global Discovery Chemistry, Novartis Biomedical Research, Emeryville, California 94608, United States., Knapp M; Global Discovery Chemistry, Novartis Biomedical Research, Emeryville, California 94608, United States., Holzinger S; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Buhr S; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Muller L; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Leder L; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Xie L; Discovery Sciences, Novartis Biomedical Research, Emeryville, California 94608, United States., Fernandez C; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Nieto-Oberhuber C; Global Discovery Chemistry, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Chène P; Disease area Oncology, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Galli GG; Disease area Oncology, Novartis Biomedical Research, CH-4056 Basel, Switzerland., Sesterhenn F; Discovery Sciences, Novartis Biomedical Research, CH-4056 Basel, Switzerland.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2024 May 17; Vol. 19 (5), pp. 1142-1150. Date of Electronic Publication: 2024 Apr 24.

Clinician approaches to new spine pain cases in primary care: Balance of opioid prescribing and early linkage to exercise therapy and spinal manipulation.

Autor: Bauer MR; Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, USA., Richard P; Preventive Medicine & Biostatistics, Uniformed Services University, Bethesda, Maryland, USA., Ritter G; Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, USA., Yoon J; Preventive Medicine & Biostatistics, Uniformed Services University, Bethesda, Maryland, USA., Larson MJ; Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, USA.

Publikováno v: Journal of evaluation in clinical practice [J Eval Clin Pract] 2024 Apr; Vol. 30 (3), pp. 355-366. Date of Electronic Publication: 2023 Dec 07.

Author Correction: Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants.

Autor: Welch NL; Broad Institute of MIT and Harvard, Cambridge, MA, USA. nicole_welch@g.harvard.edu.; Harvard Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA, USA. nicole_welch@g.harvard.edu., Zhu M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Hua C; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Weller J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Mirhashemi ME; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen TG; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mantena S; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bauer MR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, USA., Shaw BM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Ackerman CM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Thakku SG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Health Sciences and Technology, Harvard Medical School and Massachusetts Institute of Technology, Cambridge, MA, USA., Tse MW; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Kehe J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Uwera MM; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Eversley JS; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Bielwaski DA; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., McGrath G; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Braidt J; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Johnson J; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Cerrato F; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Moreno GK; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Krasilnikova LA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Petros BA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Health Sciences and Technology, Harvard Medical School and Massachusetts Institute of Technology, Cambridge, MA, USA.; Harvard/Massachusetts Institute of Technology MD-PhD Program, Harvard Medical School, Boston, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Gionet GL; Broad Institute of MIT and Harvard, Cambridge, MA, USA., King E; State Health Laboratories, Rhode Island Department of Health, Providence, RI, USA., Huard RC; State Health Laboratories, Rhode Island Department of Health, Providence, RI, USA., Jalbert SK; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Cleary ML; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Fitzgerald NA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gabriel SB; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gallagher GR; Massachusetts Department of Public Health, Boston, MA, USA., Smole SC; Massachusetts Department of Public Health, Boston, MA, USA., Madoff LC; Massachusetts Department of Public Health, Boston, MA, USA., Brown CM; Massachusetts Department of Public Health, Boston, MA, USA., Keller MW; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Wilson MM; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Kirby MK; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Barnes JR; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA., Park DJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Siddle KJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA., Happi CT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; African Centre of Excellence for Genomics of Infectious Diseases, Redeemer's University, Ede, Nigeria.; Department of Biological Sciences, College of Natural Sciences, Redeemer's University, Ede, Nigeria., Hung DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Molecular Biology Department and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA., Springer M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., MacInnis BL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Lemieux JE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Rosenberg E; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Branda JA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA., Blainey PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Cambridge, MA, USA., Sabeti PC; Broad Institute of MIT and Harvard, Cambridge, MA, USA. pardis@broadinstitute.org.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA. pardis@broadinstitute.org.; Department of Immunology and Infectious Disease, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA. pardis@broadinstitute.org.; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Cambridge, MA, USA. pardis@broadinstitute.org.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. pardis@broadinstitute.org., Myhrvold C; Department of Molecular Biology, Princeton University, Princeton, NJ, USA. cmyhrvol@princeton.edu.

Publikováno v: Nature medicine [Nat Med] 2024 Jan; Vol. 30 (1), pp. 307.

Pan-viral ORFs discovery using Massively Parallel Ribosome Profiling.

Autor: Weingarten-Gabbay S, Bauer MR, Stanton AC, Klaeger S, Verzani EK, López D, Clauser KR, Carr SA, Abelin JG, Rice CM, Sabeti PC

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 28. Date of Electronic Publication: 2023 Sep 28.