Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Baud, Matthias G.J."'
Autor:
Baud, Matthias G.J., Bauer, Matthias R., Verduci, Lorena, Dingler, Felix A., Patel, Ketan J., Horil Roy, Deeptee, Joerger, Andreas C., Fersht, Alan R.
Publikováno v:
In European Journal of Medicinal Chemistry 25 May 2018 152:101-114
Autor:
Joerger, Andreas C., Bauer, Matthias R., Wilcken, Rainer, Baud, Matthias G.J., Harbrecht, Hannes, Exner, Thomas E., Boeckler, Frank M., Spencer, John, Fersht, Alan R.
Publikováno v:
In Structure 1 December 2015 23(12):2246-2255
Publikováno v:
In Analytical Biochemistry 1 September 2014 460:39-46
PROteolysis TArgeting Chimeras (PROTACs) are heterobifunctional molecules consisting of two ligands; an “anchor” to bind to an E3 ubiquitin ligase and a “warhead” to bind to a protein of interest, connected by a chemical linker. Targeted prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::2a440b67587c6674fcd45cffbc14acc4
https://eprints.soton.ac.uk/444970/
https://eprints.soton.ac.uk/444970/
Autor:
Chasov, Vitaly, Mirgayazova, Regina, Zmievskaya, Ekaterina, Khadiullina, Raniya, Valiullina, Aygul, Stephenson Clarke, Joseph Richard, Rizvanov, Albert, Baud, Matthias G.J., Bulatov, Emil
The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the TP53 gene or overexpression of its negative regulators. The p53 protein is known as the “cellular gatekeeper” fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______348::90d8be1ed1d95156659ce15032c453ae
https://eprints.soton.ac.uk/444147/
https://eprints.soton.ac.uk/444147/