Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Batuhan Mert Kalkan"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-13 (2024)
Abstract Unlike normal cells, cancer cells frequently exhibit supernumerary centrosomes, leading to formation of multipolar spindles that can trigger cell death. Nevertheless, cancer cells with supernumerary centrosomes escape the deadly consequences
Externí odkaz:
https://doaj.org/article/1b57fa82279d47b4ab1e02217494b777
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Centrosome amplification is a hallmark of cancer and PLK4 is one of the responsible factors for cancer associated centrosome amplification. Increased PLK4 levels was also shown to contribute to generation of cells with centriole amplificatio
Externí odkaz:
https://doaj.org/article/d2f6b0e6efaa43f6aa52ec780668d979
Publikováno v:
Moleküler Biyoloji ve Genetik ISBN: 9786258352481
Gene editing has emerged as a powerful and high potential mechanism for a clearer understanding of biological systems and for the diagnosis and treatment of genetic diseases. With the rising trend of gene editing technology in recent years, its use i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e23902775616b3a9d00ad7add7fe5f4
https://doi.org/10.53478/tuba.978-625-8352-48-1.ch06
https://doi.org/10.53478/tuba.978-625-8352-48-1.ch06
Publikováno v:
Gene Editing. 2:22-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::432f390e73e1f565618cbacf1f44983a
https://doi.org/10.29228/genediting.54872
https://doi.org/10.29228/genediting.54872
Publikováno v:
Gene Editing. 1:21-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e79dfd9ced60460736d59e46c12c4cc7
https://doi.org/10.29228/genediting.40385
https://doi.org/10.29228/genediting.40385
Endothelial dysfunction is prominent in atherosclerosis, hypertension, diabetes, peripheral and cardiovascular diseases, and stroke. Novel therapeutic approaches to these conditions often involve development of tissue-engineered veins with ex vivo ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298f5b78bdb5159eebe88bbb772d9f7e
https://aperta.ulakbim.gov.tr/record/11613
https://aperta.ulakbim.gov.tr/record/11613
Autor:
Raife Dilek Turan, Zafer Gulbas, Serdar Durdagi, Fatih Kocabas, Neslihan Meric, Galip Servet Aslan, Merve Uslu, Batuhan Mert Kalkan, Lamia Yazgi Alyazici, Esra Albayrak, Dogacan Yucel, Emre Can Tuysuz, Merve Aksoz, Pinar Siyah
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Meis1, which belongs to TALE-type class of homeobox gene family, appeared as one of the key regulators of hematopoietic stem cell (HSC) self-renewal and a potential therapeutical target. However, small molecule inhibitors of MEIS1 remained unknown. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110638913d5b08f77ddb7852d16669a6
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8879
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8879
Autor:
Batuhan Mert Kalkan, Selahattin Can Ozcan, Nicholas J. Quintyne, Samantha L. Reed, Ceyda Acilan
Publikováno v:
Cancers, Vol 14, Iss 442, p 442 (2022)
Cancers
Cancers
Simple Summary Precise chromosome segregation during mitosis is a vital event orchestrated by formation of bipolar spindle poles. Supernumerary centrosomes, caused by centrosome amplification, deteriorates mitotic processes, resulting in segregation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ff3d90eff04f69216ea864449d3aab
https://doi.org/10.3390/cancers14020442
https://doi.org/10.3390/cancers14020442
Publikováno v:
Nutrition and Cancer. 69:1003-1010
WOS: 000415755000005
PubMed ID: 28922017
Adropin is a peptide hormone that has been implicated in insulin resistance and as a potential regulator of growth. The aim of this study is to determine the effect of calorie restriction on circulat
PubMed ID: 28922017
Adropin is a peptide hormone that has been implicated in insulin resistance and as a potential regulator of growth. The aim of this study is to determine the effect of calorie restriction on circulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9559c1103d44625d699ac54a83d17e
https://doi.org/10.1080/01635581.2017.1359314
https://doi.org/10.1080/01635581.2017.1359314
Publikováno v:
Gene
Recent developments in gene editing technology have enabled scientists to modify DNA sequence by using engineered endonucleases. These gene editing tools are promising candidates for clinical applications, especially for treatment of inherited disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d659fea1283bbae4c50fa6c61fb26e
https://pubmed.ncbi.nlm.nih.gov/31987908
https://pubmed.ncbi.nlm.nih.gov/31987908