Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

Autor: Nielsen, H.B., Almeida, M., Sierakowska Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D.R., Gautier, L., Pedersen, A.G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J.M., Quintanilha dos Santos, M.B., Blom, N., Borruel, N., Burgdorf, K.S., Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, T., Hildebrand, F., Kaas, R.S., Kennedy, S., Kristiansen, K., Kultima, J.R., Leonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, O., Prifti, E., Qin, J., Raes, J., Sørensen, S., Tap, J., Tims, S., Ussery, D.W., Yamada, T., Jamet, A., Mérieux, A., Cultrone, A., Torrejon, A., Quinquis, B., Brechot, C., Delorme, C., M'Rini, C., de Vos, W.M., Maguin, E., Varela, E., Guedon, E., Gwen, F., Haimet, F., Artiguenave, F., Vandemeulebrouck, G., Denariaz, G., Khaci, G., Blottière, H., Knol, J., Weissenbach, J., van Hylckama Vlieg, J.E., Torben, J., Parkhil, J., Turner, K., van de Guchte, M., Antolin, M., Rescigno, M., Kleerebezem, M., Derrien, M., Galleron, N., Sanchez, N., Grarup, N., Veiga, P., Oozeer, R., Dervyn, R., Layec, S., Bruls, T., Winogradski, Y., Zoetendal, E.G., Renault, D., Sicheritz-Ponten, Bork, P., Wang, J., Brunak, S., Ehrlich, S.D.

Publikováno v: Nature Biotechnology
Nature Biotechnology, Nature Publishing Group, 2014, 32, pp.822-828. ⟨10.1038/nbt.2939⟩
Nature Biotechnology, 2014, 32, pp.822-828. ⟨10.1038/nbt.2939⟩
Nature Biotechnology, Nature Publishing Group, 2014, 32 (8), pp.822-828. ⟨10.1038/nbt.2939⟩
Nature Biotechnology 32 (2014)
Nature Biotechnology, 32, 822-828
Nielsen, H B, Almeida, M, Juncker, A S, Rasmussen, S, Li, J H, Sunagawa, S, Plichta, D R, Gautier, L, Pedersen, A G, Le Chatelier, E, Pelletier, E, Bonde, I, Nielsen, T, Manichanh, C, Arumugam, M, Batto, J M, dos Santos, M B Q, Blom, N, Borruel, N, Burgdorf, K S, Boumezbeur, F, Casellas, F, Dore, J, Dworzynski, P, Guarner, F, Hansen, T, Hildebrand, F, Kaas, R S, Kennedy, S, Kristiansen, K, Kultima, J R, Leonard, P, Levenez, F, Lund, O, Moumen, B, Le Paslier, D, Pons, N, Pedersen, O, Prifti, E, Qin, J J, Raes, J, Sorensen, S, Tap, J, Tims, S, Ussery, D W, Yamada, T, Renault, P, Sicheritz-Ponten, T, Bork, P, Wang, J, Brunak, S, Ehrlich, S D & Meta, H I T C 2014, ' Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes ', Nature Biotechnology, vol. 32, no. 8, pp. 822-828 . https://doi.org/10.1038/nbt.2939

Most current approaches for analyzing metagenomic data rely on comparisons to reference genomes, but the microbial diversity of many environments extends far beyond what is covered by reference databases. De novo segregation of complex metagenomic da

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https://doi.org/10.1038/nbt.2939

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