An integrated machine-learning model to predict nucleosome architecture.

Autor: Sala A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Labrador M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Buitrago D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., De Jorge P; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Battistini F; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Departament de Bioquímica i Biomedicina, Universitat de Barcelona, Barcelona, Spain., Heath IB; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain., Orozco M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Departament de Bioquímica i Biomedicina, Universitat de Barcelona, Barcelona, Spain.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2024 Sep 23; Vol. 52 (17), pp. 10132-10143.

Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study.

Autor: Domingo JC; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain., Battistini F; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, Barcelona Institute of Science and Technology, Barcelona, 08028, Spain., Cordobilla B; Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, Barcelona, 08028, Spain., Zaragozá MC; Clinical Research Department, Laboratorios Viñas, Barcelona, 08012, Spain., Sanmartin-Sentañes R; Division of Rheumatology, Clinical Unit in ME/CFS and Long COVID, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain.; Division of Rheumatology, Research Unit in ME/CFS and Long COVID, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain., Alegre-Martin J; Division of Rheumatology, Clinical Unit in ME/CFS and Long COVID, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain.; Division of Rheumatology, Research Unit in ME/CFS and Long COVID, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain., Cambras T; Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Sciences, University of Barcelona, Barcelona, 08028, Spain. cambras@ub.edu., Castro-Marrero J; Division of Rheumatology, Research Unit in ME/CFS and Long COVID, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, Barcelona, 08035, Spain. jesus.castro@vhir.org.

Publikováno v: Journal of translational medicine [J Transl Med] 2024 Apr 10; Vol. 22 (1), pp. 343. Date of Electronic Publication: 2024 Apr 10.

The pseudotorsional space of RNA.

Autor: Grille L; Computational Biophysics Group, Department of Biological Sciences, CENUR Litoral Norte, Universidad de la República, 50000 Salto, Uruguay.; Bioinformatics Unit, Institute Pasteur of Montevideo, 11400 Montevideo, Uruguay., Gallego D; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain.; Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain., Darré L; Bioinformatics Unit, Institute Pasteur of Montevideo, 11400 Montevideo, Uruguay.; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain., da Rosa G; Computational Biophysics Group, Department of Biological Sciences, CENUR Litoral Norte, Universidad de la República, 50000 Salto, Uruguay.; Bioinformatics Unit, Institute Pasteur of Montevideo, 11400 Montevideo, Uruguay., Battistini F; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain.; Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain., Orozco M; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain modesto.orozco@irbbarcelona.org pdans@pasteur.edu.uy.; Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain., Dans PD; Computational Biophysics Group, Department of Biological Sciences, CENUR Litoral Norte, Universidad de la República, 50000 Salto, Uruguay modesto.orozco@irbbarcelona.org pdans@pasteur.edu.uy.; Bioinformatics Unit, Institute Pasteur of Montevideo, 11400 Montevideo, Uruguay.; Molecular Modelling and Bioinformatics Group, Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain.

Publikováno v: RNA (New York, N.Y.) [RNA] 2023 Dec; Vol. 29 (12), pp. 1896-1909. Date of Electronic Publication: 2023 Oct 04.

Sequence-Dependent Properties of the RNA Duplex.

Autor: Battistini F; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10, Barcelona 08028, Spain.; Departament de Bioquímica i Biomedicina. Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 647, Barcelona 08028, Spain., Sala A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10, Barcelona 08028, Spain., Hospital A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10, Barcelona 08028, Spain., Orozco M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Baldiri Reixac 10, Barcelona 08028, Spain.; Departament de Bioquímica i Biomedicina. Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 647, Barcelona 08028, Spain.

Publikováno v: Journal of chemical information and modeling [J Chem Inf Model] 2023 Aug 28; Vol. 63 (16), pp. 5259-5271. Date of Electronic Publication: 2023 Aug 14.

DNA double-strand break-derived RNA drives TIRR/53BP1 complex dissociation

Autor: Ketley, RF, Battistini, F, Alagia, A, Mondielli, C, Iehl, F, Balikçi, E, Huber, KVM, Orozco, M, Gullerova, M

Publikováno v: Cell Reports. 41:111526

Tudor-interacting repair regulator (TIRR) is an RNA-binding protein and a negative regulator of the DNA-repair factor p53-binding protein 1 (53BP1). In non-damage conditions, TIRR is bound to 53BP1. After DNA damage, TIRR and 53BP1 dissociate, and 53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5cdb6bbb4ead2c50a375b9dcc3c1c5
https://doi.org/10.1016/j.celrep.2022.111526