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pro vyhledávání: '"Batsivari A"'
Acute myeloid leukaemia (AML) is a type of blood and bone marrow cancer characterized by the proliferation of abnormal clonal haematopoietic cells in the bone marrow leading to bone marrow failure. Over the course of the disease, angiogenic factors r
Externí odkaz:
http://arxiv.org/abs/2408.13685
Autor:
Ragazzini, Roberta, Boeing, Stefan, Zanieri, Luca, Green, Mary, D’Agostino, Giuseppe, Bartolovic, Kerol, Agua-Doce, Ana, Greco, Maria, Watson, Sara A., Batsivari, Antoniana, Ariza-McNaughton, Linda, Gjinovci, Asllan, Scoville, David, Nam, Andy, Hayday, Adrian C., Bonnet, Dominique, Bonfanti, Paola
Publikováno v:
In Developmental Cell 20 November 2023 58(22):2428-2446
Publikováno v:
In Experimental Hematology March 2021 95:23-30
Autor:
Jordi Senserrich, Antoniana Batsivari, Stanislav Rybtsov, Sabrina Gordon-Keylock, Celine Souilhol, Frank Buchholz, David Hills, Suling Zhao, Alexander Medvinsky
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 784-794 (2018)
Summary: Hematopoietic stem cells (HSCs) develop in the embryonic aorta-gonad-mesonephros (AGM) region and subsequently relocate to fetal liver. Runx1 transcription factor is essential for HSC development, but is largely dispensable for adult HSCs. H
Externí odkaz:
https://doaj.org/article/851d86e7be5145f9bcaefdd38479858f
Autor:
Antoniana Batsivari, Stanislav Rybtsov, Celine Souilhol, Anahi Binagui-Casas, David Hills, Suling Zhao, Paul Travers, Alexander Medvinsky
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1549-1562 (2017)
During development, hematopoietic stem cells (HSCs) emerge in the aorta-gonad-mesonephros (AGM) region through a process of multi-step maturation and expansion. While proliferation of adult HSCs is implicated in the balance between self-renewal and d
Externí odkaz:
https://doaj.org/article/25c2bb5e9d1e49d6b291aff2434a5e81
Autor:
Souilhol, Céline *, Lendinez, Javier G. *, Rybtsov, Stanislav, Murphy, Fiona, Wilson, Heather, Hills, David, Batsivari, Antoniana, Binagui-Casas, Anahí, McGarvey, Alison C., MacDonald, H.Robson, Kageyama, Ryoichiro, Siebel, Christian, Zhao, Suling, Medvinsky, Alexander
Publikováno v:
In Blood 22 September 2016 128(12):1567-1577
Autor:
Céline Souilhol, Christèle Gonneau, Javier G. Lendinez, Antoniana Batsivari, Stanislav Rybtsov, Heather Wilson, Lucia Morgado-Palacin, David Hills, Samir Taoudi, Jennifer Antonchuk, Suling Zhao, Alexander Medvinsky
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
It is unclear how the microenvironment of the aorta-gonad-mesonephros influences haematopoietic stem cell (HSC) production early in mouse development. Here, Souilhol et al. use an in vitroaggregate system as a tool to understand how several pathways,
Externí odkaz:
https://doaj.org/article/efd4191028d64fedbaefeee46e52bec3
Autor:
Stanislav Rybtsov, Antoniana Batsivari, Kateryna Bilotkach, Daria Paruzina, Jordi Senserrich, Oleg Nerushev, Alexander Medvinsky
Publikováno v:
Stem Cell Reports, Vol 3, Iss 3, Pp 489-501 (2014)
Definitive hematopoietic stem cells (HSCs) develop in the aorta gonad mesonephros (AGM) region in a stepwise manner. Type I pre-HSCs express CD41 but lack CD45 expression, which is subsequently upregulated in type II pre-HSCs prior to their maturatio
Externí odkaz:
https://doaj.org/article/cbe06e1d40b042bc9290a69543d0d1dd
Autor:
Diana Passaro, Antoniana Batsivari, Constandina Pospori, Cristina Lo Celso, Myriam L. R. Haltalli, Dominique Bonnet
Publikováno v:
Nature Cell Biology. 22:7-17
Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal and haematopoietic cells regulate their function. The steady state HSC niche has been extensively studied. In this Review, we focus on how bone marrow microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020171ba8566c8cf2b2e3b29edf7e2bc
https://doi.org/10.1038/s41556-019-0444-9
https://doi.org/10.1038/s41556-019-0444-9
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells
Autor:
Ander Abarrategi, Henry Wood, Alexander E. Smith, Kar Lok Kong, Syed A Mian, Linda Ariza-McNaughton, Thomas Snoeks, Peter Johnson, Caroline A. Oedekoven, Ghulam J. Mufti, Kevin Rouault-Pierre, Antoniana Batsivari, Dominique Bonnet
Publikováno v:
Blood Cancer Discov
Myelodysplastic syndromes (MDS) are clonal stem cell diseases characterized mainly by ineffective hematopoiesis. Here, we present an approach that enables robust long-term engraftment of primary MDS stem cells (MDS-SC) in mice by implantation of huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5881a32be05364aa192a74f978a5b05
https://pubmed.ncbi.nlm.nih.gov/33778768
https://pubmed.ncbi.nlm.nih.gov/33778768