Zobrazeno 1 - 10
of 660
pro vyhledávání: '"Batch Effect"'
Autor:
Richard Van, Daniel Alvarez, Travis Mize, Sravani Gannavarapu, Lohitha Chintham Reddy, Fatma Nasoz, Mira V. Han
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract Background RNA sequencing combined with machine learning techniques has provided a modern approach to the molecular classification of cancer. Class predictors, reflecting the disease class, can be constructed for known tissue types using the
Externí odkaz:
https://doaj.org/article/1f53e28f104c412b8a2fb317eca5b915
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract In recent years, the integration of single‐cell multi‐omics data has provided a more comprehensive understanding of cell functions and internal regulatory mechanisms from a non‐single omics perspective, but it still suffers many challe
Externí odkaz:
https://doaj.org/article/98e6088521e44117aefc1ba90428a549
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Numerous single‐cell transcriptomic datasets from identical tissues or cell lines are generated from different laboratories or single‐cell RNA sequencing (scRNA‐seq) protocols. The denoising of these datasets to eliminate batch effects
Externí odkaz:
https://doaj.org/article/aa22a46114ce47659d45ec869977b01a
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
MicroRNAs (miRNAs) are promising biomarkers for the early detection of disease, and many miRNA-based diagnostic models have been constructed to distinguish patients and healthy individuals. To thoroughly utilize the miRNA-profiling data across differ
Externí odkaz:
https://doaj.org/article/6a0ff5b3db07460ba8df22ccd0d7270f
Autor:
Yujin Jang, Hye-Won Na, Dong Yeop Shin, Jun Lee, Jun Pyo Han, Hyun Soo Kim, Su Ji Kim, Eun-Jeong Choi, Charles Lee, Yong Deog Hong, Hyoung-June Kim, Young Rok Seo
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundUltraviolet B (UVB) from sunlight represents a major environmental factor that causes toxic effects resulting in structural and functional cutaneous abnormalities in most living organisms. Although numerous studies have indicated the biolog
Externí odkaz:
https://doaj.org/article/68c5d9eefa724e088e724fee444994f6
Autor:
Ying Yu, Naixin Zhang, Yuanbang Mai, Luyao Ren, Qiaochu Chen, Zehui Cao, Qingwang Chen, Yaqing Liu, Wanwan Hou, Jingcheng Yang, Huixiao Hong, Joshua Xu, Weida Tong, Lianhua Dong, Leming Shi, Xiang Fang, Yuanting Zheng
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background Batch effects are notoriously common technical variations in multiomics data and may result in misleading outcomes if uncorrected or over-corrected. A plethora of batch-effect correction algorithms are proposed to facilitate data
Externí odkaz:
https://doaj.org/article/12d1f02d68834a36afdf46f129f91b1b
Autor:
Patrick M. Carry, Tim Vigers, Lauren A. Vanderlinden, Carson Keeter, Fran Dong, Teresa Buckner, Elizabeth Litkowski, Ivana Yang, Jill M. Norris, Katerina Kechris
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background We developed a novel approach to minimize batch effects when assigning samples to batches. Our algorithm selects a batch allocation, among all possible ways of assigning samples to batches, that minimizes differences in average pr
Externí odkaz:
https://doaj.org/article/f5f3161d1212472ba1fb4cc3ce02231b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4804-4815 (2023)
The human microbiome is an emerging research frontier due to its profound impacts on health. High-throughput microbiome sequencing enables studying microbial communities but suffers from analytical challenges. In particular, the lack of dedicated pre
Externí odkaz:
https://doaj.org/article/455954e4c90b418396db2c5ed9be092e
Publikováno v:
Genes, Vol 15, Iss 1, p 67 (2024)
Genome-wide association studies (GWAS) have successfully revealed many disease-associated genetic variants. For a case-control study, the adequate power of an association test can be achieved with a large sample size, although genotyping large sample
Externí odkaz:
https://doaj.org/article/c4313c4452344613b1c19adf749f978c
Autor:
Aziz Fouché, Andrei Zinovyev
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Important quantities of biological data can today be acquired to characterize cell types and states, from various sources and using a wide diversity of methods, providing scientists with more and more information to answer challenging biological ques
Externí odkaz:
https://doaj.org/article/6d98fbdb5b3241bd9b8020d9c1e06e7c