Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Basuthkar J. Rao"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-12 (2024)
Abstract Background Poly(ADP-ribose) polymerase-1 (PARP-1) is a pan nuclear protein that utilizes NAD+ as a substrate for poly(ADP-ribosyl)ation reaction (PARylation), resulting in both auto-modification and the modification of its accepter proteins.
Externí odkaz:
https://doaj.org/article/06288f3351124349ae573102532c09e2
Autor:
Sandeep Chakraborty, Rafael Nascimento, Paulo A. Zaini, Hossein Gouran, Basuthkar J. Rao, Luiz R. Goulart, Abhaya M. Dandekar
Publikováno v:
PeerJ, Vol 4, p e2007 (2016)
Background. Xylella fastidiosa, the causative agent of various plant diseases including Pierce’s disease in the US, and Citrus Variegated Chlorosis in Brazil, remains a continual source of concern and economic losses, especially since almost all co
Externí odkaz:
https://doaj.org/article/05121bafd6a54501a5fa145aa00f8cfc
Autor:
Sandeep Chakraborty, Monica Britton, Jill Wegrzyn, Timothy Butterfield, Pedro José Martínez-García, Russell L. Reagan, Basuthkar J. Rao, Charles A. Leslie, Mallikarjuna Aradhaya, David Neale, Keith Woeste, Abhaya M. Dandekar
Publikováno v:
F1000Research, Vol 4 (2015)
The transcriptome provides a functional footprint of the genome by enumerating the molecular components of cells and tissues. The field of transcript discovery has been revolutionized through high-throughput mRNA sequencing (RNA-seq). Here, we presen
Externí odkaz:
https://doaj.org/article/9d15363dcafd430da6b7347db368bdb9
Autor:
Sandeep Chakraborty, My Phu, Tâmara Prado de Morais, Rafael Nascimento, Luiz Ricardo Goulart, Basuthkar J. Rao, Bjarni Asgeirsson, Abhaya M. Dandekar
Publikováno v:
F1000Research, Vol 3 (2015)
The therapeutic potential of α-helical anti-microbial peptides (AH-AMP) to combat pathogens is fast gaining prominence. Based on recently published open access software for characterizing α-helical peptides (PAGAL), we elucidate a search methodolog
Externí odkaz:
https://doaj.org/article/a4e85d41f1ef4e55abe799cba48007d3
Publikováno v:
F1000Research, Vol 3 (2015)
Alpha helices (AH) are peptide fragments characterized by regular patterns of hydrogen bonding between the carbonyl oxygen and amino nitrogen of residues regularly spaced in sequence, resulting in spiral conformations. Their preponderance in protein
Externí odkaz:
https://doaj.org/article/db6ba03c9a774deea597e36c177704bf
Autor:
Sandeep Chakraborty, Adela Rendón-Ramírez, Bjarni Ásgeirsson, Mouparna Dutta, Anindya S. Ghosh, Masataka Oda, Ravindra Venkatramani, Basuthkar J. Rao, Abhaya M. Dandekar, Félix M. Goñi
Publikováno v:
F1000Research, Vol 2 (2015)
The long term side effects of any newly introduced drug is a subject of intense research, and often raging controversies. One such example is the dipeptidyl peptidase-IV (DPP4) inhibitor used for treating type 2 diabetes, which is inconclusively impl
Externí odkaz:
https://doaj.org/article/63440a96bf5e4b6d9c898d0f685f1a13
Autor:
Sandeep Chakraborty, Adela Rendón-Ramírez, Bjarni Ásgeirsson, Mouparna Dutta, Anindya S. Ghosh, Masataka Oda, Ravindra Venkatramani, Basuthkar J. Rao, Abhaya M. Dandekar, Félix M. Goñi
Publikováno v:
F1000Research, Vol 2 (2015)
The long term side effects of any newly introduced drug is a subject of intense research, and often raging controversies. One such example is the dipeptidyl peptidase-IV (DPP4) inhibitor used for treating type 2 diabetes, which is inconclusively impl
Externí odkaz:
https://doaj.org/article/d216af978bfc49edb2d3e0f0d47f112e
Publikováno v:
F1000Research, Vol 3 (2015)
Ebola, considered till recently as a rare and endemic disease, has dramatically transformed into a potentially global humanitarian crisis. The genome of Ebola, a member of the Filoviridae family, encodes seven proteins. Based on the recently implemen
Externí odkaz:
https://doaj.org/article/50d59dfa43d44fc79ad544bdc82153ab
Publikováno v:
F1000Research, Vol 3 (2014)
Duplication of genes is one of the preferred ways for natural selection to add advantageous functionality to the genome without having to reinvent the wheel with respect to catalytic efficiency and protein stability. The duplicated secretory virulenc
Externí odkaz:
https://doaj.org/article/03beffc00a774381a846620b04fb3822
Autor:
Sandeep Chakraborty, Ravindra Venkatramani, Basuthkar J. Rao, Bjarni Asgeirsson, Abhaya M. Dandekar
Publikováno v:
F1000Research, Vol 2 (2014)
The structure of a protein provides insight into its physiological interactions with other components of the cellular soup. Methods that predict putative structures from sequences typically yield multiple, closely-ranked possibilities. A critical com
Externí odkaz:
https://doaj.org/article/bd033d47cf1e4bbfba551bf26135c8dc