Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Bastien Michelet"'
Autor:
Paul Bourbon, Kassandra Vitse, Agnès Martin-Mingot, Hugo Geindre, Frédéric Guégan, Bastien Michelet, Sébastien Thibaudeau
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Electrophilic aromatic substitution is one of the most mechanistically studied reactions in organic chemistry. However, precluded by innate substituent effects, the access to certain substitution patterns remains elusive. While selective C
Externí odkaz:
https://doaj.org/article/ff1f36c124ea457eaf96656b8a8109c1
Autor:
Clément Jacob, Hajar Baguia, Amaury Dubart, Samuel Oger, Pierre Thilmany, Jérôme Beaudelot, Christopher Deldaele, Stefano Peruško, Yohann Landrain, Bastien Michelet, Samuel Neale, Eugénie Romero, Cécile Moucheron, Veronique Van Speybroeck, Cédric Theunissen, Gwilherm Evano
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The construction of four-membered rings via a 4-exo-dig cyclization was originally theorized to be unfavourable and only recently shown in sparse examples. Here the authors present a photochemical, radical 4-exo-dig cyclization of ynamides to form az
Externí odkaz:
https://doaj.org/article/74a30cbf227b4922802fd7718b8ea522
Autor:
Anthony J. Fernandes, Armen Panossian, Bastien Michelet, Agnès Martin-Mingot, Frédéric R. Leroux, Sébastien Thibaudeau
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 343-378 (2021)
“The extraordinary instability of such an “ion” accounts for many of the peculiarities of organic reactions” – Franck C. Whitmore (1932). This statement from Whitmore came in a period where carbocations began to be considered as intermediat
Externí odkaz:
https://doaj.org/article/9c3ca6c7d8564a85b5a47c26c441c400
Autor:
Anthony J. Fernandes, Bastien Michelet, Armen Panossian, Agnès Martin-Mingot, Frédéric R. Leroux, Sébastien Thibaudeau
Publikováno v:
Chemical Communications. 59:4083-4086
We report on the dramatic effect of a local partial charge inversion by replacing a CHCH3 group by a CFCF3. This strategy allows the diastereoselective reduction of 5-membered ring oxocarbenium ions to access highly substituted tetrahydrofurans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5afce090c39b6c6a2b6aad11c19db5d0
https://doi.org/10.1039/d2cc06521e
https://doi.org/10.1039/d2cc06521e
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, In press, ⟨10.1002/chem.202300440⟩
Chemistry-A European Journal, In press, ⟨10.1002/chem.202300440⟩
International audience; Since the pioneer reports of Akiyama and Terada groups on Brønsted acid organocatalysis, this field never stopped growing with the development of ingenious strategies for the activation of challenging poorly reactive substrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c0348b1e44373f3f94d951a9f635a7
https://hal.science/hal-04047011/file/Concept_OrgaSup_HAL.pdf
https://hal.science/hal-04047011/file/Concept_OrgaSup_HAL.pdf
Autor:
Christopher Deldaele, Bastien Michelet, Hajar Baguia, Sofia Kajouj, Eugenie Romero, Cecile Moucheron, Gwilherm Evano
Publikováno v:
CHIMIA, Vol 72, Iss 9 (2018)
Organic transformations can broadly be classified into four categories including cationic, anionic, pericyclic and radical reactions. While the last category has been known for decades to provide remarkably efficient synthetic pathways, it has long b
Externí odkaz:
https://doaj.org/article/20ec60fa53c44d8699e57ad9d265853a
Autor:
Claudiu T. Supuran, Emanuela Berrino, Sébastien Thibaudeau, Bastien Michelet, Fabrizio Carta, Agnès Martin-Mingot
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, In press, ⟨10.1002/anie.202103211⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, In press, ⟨10.1002/anie.202103211⟩
International audience; The insertion of fluorine atoms and/or fluoroalkyl groups can lead to many beneficial effects in biologically active molecules, such as enhanced metabolic stability, bioavailability, lipophilicity, and membrane permeability, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04ab68f4948f2c6140ca604e7382d4b
https://doi.org/10.1002/ange.202103211
https://doi.org/10.1002/ange.202103211
Autor:
Emeline Appert, Agnès Martin‐Mingot, Omar Karam, Fabien Zunino, Bastien Michelet, Fodil Bouazza, Sébastien Thibaudeau
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(49)
The field of medicinal chemistry is currently witnessing a deuterium rush owing to the remarkable properties of this element as bioisoster of hydrogen atom. Aromatic hydrogen isotope exchange (HIE) is one of the most studied strategies nowadays as it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272a4f6b955a9aa6c56bef85e8eca3d6
https://pubmed.ncbi.nlm.nih.gov/35689822
https://pubmed.ncbi.nlm.nih.gov/35689822
Autor:
Jérôme Désiré, Naresh Bhuma, Agnès Martin-Mingot, Jesús Jiménez-Barbero, Bastien Michelet, Yves Blériot, Zahra Abada, Aiichiro Nagaki, Sébastien Thibaudeau, Jérôme Marrot, Ludivine Lebedel, Ana Ardá, Masahiro Takumi, Hiroki Yamashita, Ali Abou-Hassan, Yutaka Shimizu
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (4), pp.2036-2041. ⟨10.1002/anie.202010175⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (4), pp.2036-2041. ⟨10.1002/anie.202010175⟩
International audience; The transformation of glycals into 2,3-unsaturated glycosyl derivatives, reported by Ferrier in 1962, is supposed to involve an α,β unsaturated glycosyl cation, an elusive ionic species that has still to be observed experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e3faebd507ea16cb5c14e2df33c14e
https://doi.org/10.1002/ange.202010175
https://doi.org/10.1002/ange.202010175
Autor:
Bastien Michelet, Frédéric Lecornué
Publikováno v:
Comprehensive Heterocyclic Chemistry IV ISBN: 9780128186565
Comprehensive Heterocyclic Chemistry IV
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2021, ⟨10.1016/B978-0-12-818655-8.00153-0⟩
Comprehensive Heterocyclic Chemistry IV
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, 2021, ⟨10.1016/B978-0-12-818655-8.00153-0⟩
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db150b64f73030bc2feae47481fcd906
https://doi.org/10.1016/b978-0-12-818655-8.00153-0
https://doi.org/10.1016/b978-0-12-818655-8.00153-0