Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Bastien Mangeat"'
Autor:
Daniel Alpern, Vincent Gardeux, Julie Russeil, Bastien Mangeat, Antonio C. A. Meireles-Filho, Romane Breysse, David Hacker, Bart Deplancke
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Despite its widespread use, RNA-seq is still too laborious and expensive to replace RT-qPCR as the default gene expression analysis method. We present a novel approach, BRB-seq, which uses early multiplexing to produce 3′ cDNA libraries fo
Externí odkaz:
https://doaj.org/article/e289bfac90334ee397207a5add15836d
Autor:
Philip V'kovski, Mitra Gultom, Jenna N Kelly, Silvio Steiner, Julie Russeil, Bastien Mangeat, Elisa Cora, Joern Pezoldt, Melle Holwerda, Annika Kratzel, Laura Laloli, Manon Wider, Jasmine Portmann, Thao Tran, Nadine Ebert, Hanspeter Stalder, Rune Hartmann, Vincent Gardeux, Daniel Alpern, Bart Deplancke, Volker Thiel, Ronald Dijkman
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001158 (2021)
Since its emergence in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread globally and become a major public health burden. Despite its close phylogenetic relationship to SARS-CoV, SARS-CoV-2 exhibits increased hum
Externí odkaz:
https://doaj.org/article/4947e0abbc4d4c3a9adf0701b3b2f770
Inhibition of HIV-1 replication by balsamin, a ribosome inactivating protein of Momordica balsamina.
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73780 (2013)
Ribosome-inactivating proteins (RIPs) are endowed with several medicinal properties, including antiviral activity. We demonstrate here that the recently identified type I RIP from Momordica balsamina also possesses antiviral activity, as determined b
Externí odkaz:
https://doaj.org/article/89c9da2cc0f34cfe9ed4baff0c38c0df
Autor:
Vincent Gardeux, Melle Holwerda, Philip V'kovski, Elisa Cora, Jasmine Portmann, Laura Laloli, Bart Deplancke, Manon Wider, Joern Pezoldt, Volker Thiel, Daniel Alpern, Silvio Steiner, Jenna N. Kelly, Nadine Ebert, Mitra Gultom, Hanspeter Stalder, Julie Russeil, Annika Kratzel, Bastien Mangeat, Thao Dang-Hien Tran, Rune Hartmann, Ronald Dijkman
The human conductive respiratory tract spans a long anatomical distance and represents an important barrier to constrain invading respiratory pathogens. The disparate ambient temperatures found in the upper and lower respiratory tract have been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43b51a0bd6e0bedbf23994e138ea2077
https://doi.org/10.1101/2020.04.27.062315
https://doi.org/10.1101/2020.04.27.062315
Autor:
Martin Lehmann, Susana Rocha, Bastien Mangeat, Fabien Blanchet, Hiroshi Uji-I, Johan Hofkens, Vincent Piguet
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002456 (2011)
Virus assembly and interaction with host-cell proteins occur at length scales below the diffraction limit of visible light. Novel super-resolution microscopy techniques achieve nanometer resolution of fluorescently labeled molecules. The cellular res
Externí odkaz:
https://doaj.org/article/c972fbdf29cb400091b57aedba59c2a3
Autor:
Bastien Mangeat, Gustavo Gers-Huber, Martin Lehmann, Madeleine Zufferey, Jeremy Luban, Vincent Piguet
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000574 (2009)
Host cells impose a broad range of obstacles to the replication of retroviruses. Tetherin (also known as CD317, BST-2 or HM1.24) impedes viral release by retaining newly budded HIV-1 virions on the surface of cells. HIV-1 Vpu efficiently counteracts
Externí odkaz:
https://doaj.org/article/44a0c442744b443baf920336e2d7e616
Autor:
Kun-Lin Zhang, Bastien Mangeat, Millan Ortiz, Vincent Zoete, Didier Trono, Amalio Telenti, Olivier Michielin
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e378 (2007)
APOBEC3G (apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G) has antiretroviral activity associated with the hypermutation of viral DNA through cytosine deamination. APOBEC3G has two cytosine deaminase (CDA) domains; the catalytical
Externí odkaz:
https://doaj.org/article/fb0246ab8b2747609402aa97536c7f8f
Publikováno v:
Haematologica, Vol 92, Iss 1 (2007)
We describe a point mutation creating an additional ATG codon in the 5′ untranslated region (UTR) of the HAMP gene, in a patient with juvenile hemochromatosis. By transient in vitro transfection studies, we provide evidence that the additional ATG
Externí odkaz:
https://doaj.org/article/e6600fcbc0a64c9fa74ce4a957cdaf46
Autor:
Ursula Berka, Thomas P. Monath, Mark R. Schleiss, Claudia Fernández-Alarcón, Michael G. Schwendinger, Jason C. Zabeli, Peter A. Gillis, Mario Aistleithner, Anders Lilja, Elizabeth C. Swanson, Farshad Guirakhoo, Bastien Mangeat, Daniel D. Pinschewer, Elizabeth M. Watson, Bettina Kiefmann, Klaus Orlinger, Nelmary Hernandez-Alvarado
Publikováno v:
Clinical and Vaccine Immunology. 24
Subunit vaccines for prevention of congenital cytomegalovirus (CMV) infection based on glycoprotein B (gB) and pp65 are in clinical trials, but it is unclear whether simultaneous vaccination with both antigens enhances protection. We undertook evalua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2611f54e93c5eb579454e1c39d38c18
https://doi.org/10.1128/cvi.00300-16
https://doi.org/10.1128/cvi.00300-16
Autor:
Thomas P. Monath, Quazim A. Alayo, Christine A. Bricault, Jessica Jimenez, Daniel D. Pinschewer, Dan H. Barouch, Jennifer L. Shields, Bastien Mangeat, Gerhard Fuhrmann, Klaus Orlinger, Pablo Penaloza MacMaster, Abishek Chandrashekar, Anders Lilja, Matthew Lim, Jade Mondesir, M. Justin Iampietro, Nicholas M. Provine, Crystal Cabral, Andreas Aspoeck, Joseph M Cabral, Michael S. Seaman
Publikováno v:
Vaccine. 35(1)
An important focus in vaccine research is the design of vaccine vectors with low seroprevalence and high immunogenicity. Replication-incompetent lymphocytic choriomeningitis virus (rLCMV) vectors do not elicit vector-neutralizing antibody responses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa332fd93d7758cb40287ce054905ad4
https://pubmed.ncbi.nlm.nih.gov/27899229
https://pubmed.ncbi.nlm.nih.gov/27899229