Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Bastian Schirmer"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2015 (2022)
The annual meeting “Signal Transduction—Receptors, Mediators and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference which is open to all scientists sharing a common interest in the elucidation of the signaling pa
Externí odkaz:
https://doaj.org/article/153fef6c9f66458da3b05aa9ce59d786
Autor:
Bastian Schirmer, Detlef Neumann
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6116 (2021)
Histamine is a pleiotropic mediator involved in a broad spectrum of (patho)-physiological processes, one of which is the regulation of inflammation. Compounds acting on three out of the four known histamine receptors are approved for clinical use. Th
Externí odkaz:
https://doaj.org/article/8d849892688943ac8e6bfcd527256280
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8, p 2728 (2020)
The annual meeting “Signal Transduction–Receptors, Mediators and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating the signalling pathways underl
Externí odkaz:
https://doaj.org/article/6aa59d566d544698a16f65795fad3425
Autor:
Bastian Schirmer, Tamina Rother, Inga Bruesch, Andre Bleich, Christopher Werlein, Danny Jonigk, Roland Seifert, Detlef Neumann
Publikováno v:
Cancers, Vol 12, Iss 4, p 912 (2020)
Colorectal cancer (CRC), a severe complication of inflammatory bowel diseases, is a common type of cancer and accounts for high mortality. CRC can be modeled in mice by application of the tumor promoter, azoxymethane (AOM), in combination with dextra
Externí odkaz:
https://doaj.org/article/6fc268a173784a2e8d804477729b7fdb
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Our previous in vitro studies revealed that histamine via histamine the H4-receptors (H4R), as compared to other stimuli, such as eotaxin or formylpeptides, rather partially activates eosinophilic granulocytes (eosinophils). In order to evaluate the
Externí odkaz:
https://doaj.org/article/3e440553c5554c49a88468371c15218b
Autor:
Antje Munder, Justin Rothschuh, Bastian Schirmer, Jens Klockgether, Volkhard Kaever, Burkhard Tümmler, Roland Seifert, Christina Kloth
Publikováno v:
Open Biology, Vol 8, Iss 1 (2018)
The nucleotidyl cyclase ExoY is an effector protein of the type III secretion system of Pseudomonas aeruginosa. We compared the cyclic nucleotide production and lung disease phenotypes caused by the ExoY-overexpressing strain PA103ΔexoUexoT::Tc pUCP
Externí odkaz:
https://doaj.org/article/89467645a4ac471b82c16adc4769651a
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Inflammatory bowel diseases (IBD) are a growing health problem worldwide, severely affecting patients’ life qualities and life expectancies. Therapeutic options, which are rare and focus on symptoms associated with the disease, suffer from increasi
Externí odkaz:
https://doaj.org/article/71cc7e39ed824a47be549e6ada07873f
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 227 (2019)
The annual meeting “Signal Transduction—Receptors, Mediators, and Genes” of the Signal Transduction Society (STS) is an interdisciplinary conference open to all scientists sharing the common interest in elucidating signaling pathways in physiol
Externí odkaz:
https://doaj.org/article/7e5a4893f5354ccc8dc0a90ef93bbfa5
Autor:
Christina Kloth, Bastian Schirmer, Antje Munder, Tane Stelzer, Justin Rothschuh, Roland Seifert
Publikováno v:
Toxins, Vol 10, Iss 5, p 185 (2018)
The effector protein Exotoxin Y (ExoY) produced by Pseudomonas aeruginosa is injected via the type III secretion system (T3SS) into host cells. ExoY acts as nucleotidyl cyclase promoting the intracellular accumulation of cyclic nucleotides. To what e
Externí odkaz:
https://doaj.org/article/bab62ec677c44f90b837c3653e5cf805
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 549 (2018)
The annual “Joint Meeting Signal Transduction—Receptors, Mediators and Genes” of the Signal Transduction Society (STS) aims to be an interdisciplinary forum for researchers who share a common interest in deciphering signal transduction pathways
Externí odkaz:
https://doaj.org/article/4d02483f6fea45bc9187a125181cd69c