Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Bastian Grewe"'
Autor:
Han Xiao, Emanuel Wyler, Miha Milek, Bastian Grewe, Philipp Kirchner, Arif Ekici, Ana Beatriz Oliveira Villela Silva, Doris Jungnickl, Florian Full, Marco Thomas, Markus Landthaler, Armin Ensser, Klaus Überla
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
To regulate its complex splicing pattern, HIV-1 uses the adaptor protein Rev to shuttle unspliced or partially spliced mRNA from the nucleus to the cytoplasm. In the absence of Rev, these RNAs are retained in the nucleus, but it is unclear why.
Externí odkaz:
https://doaj.org/article/024fe1f1a6964e11a3329f44d73767b6
Autor:
Bastian Grewe, Carolin Vogt, Theresa Horstkötter, Bettina Tippler, Han Xiao, Bianca Müller, Klaus Überla, Ralf Wagner, Benedikt Asbach, Jens Bohne
Publikováno v:
Viruses, Vol 13, Iss 6, p 997 (2021)
Alternative splicing and the expression of intron-containing mRNAs is one hallmark of HIV gene expression. To facilitate the otherwise hampered nuclear export of non-fully processed mRNAs, HIV encodes the Rev protein, which recognizes its intronic re
Externí odkaz:
https://doaj.org/article/40ddbf640e3d4a809ead9ac669da9792
Autor:
Bianca Hoffmann, Bastian Grewe
Publikováno v:
Bio-Protocol, Vol 3, Iss 8 (2013)
Formation of viral particles and packaging of genomic retroviral RNA into these particles are important steps in the late phase of the viral replication cycle. The efficiency of the incorporation of viral or cellular RNAs into viral particles can be
Externí odkaz:
https://doaj.org/article/548e63926c9141c1827c7c7fe95391ee
Autor:
Bianca Hoffmann, Bastian Grewe
Publikováno v:
Bio-Protocol, Vol 3, Iss 8 (2013)
Using a Reverse Transcriptase-PCR approach spliced transcripts can be converted to cDNA, amplified and cloned into an expression plasmid. Sequencing of the obtained cDNA allows identification of the splicing events that generated the detected RNA (Gr
Externí odkaz:
https://doaj.org/article/fb03ad62d6ad495a8c134e5e94d1b7ee
Autor:
Donatien Kamdem Toukam, Matthias Tenbusch, Alexander Stang, Vladimir Temchura, Michael Storcksdieck Genannt Bonsmann, Bastian Grewe, Stefanie Koch, Andreas Meyerhans, Godwin Nchinda, Lazare Kaptue, Klaus Uberla
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38068 (2012)
Although human immunodeficiency type 1 (HIV-1) infection induces strong antibody responses to the viral envelope glycoprotein (Env) only a few of these antibodies possess the capacity to neutralize a broad range of strains. The induction of such anti
Externí odkaz:
https://doaj.org/article/852b5bbc0dad4f00874c8b39feb31fb8
Autor:
Bastian Grewe, Katrin Ehrhardt, Bianca Hoffmann, Maik Blissenbach, Sabine Brandt, Klaus Uberla
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48688 (2012)
BACKGROUND: During the RNA encapsidation process of human immunodeficiency virus (HIV) viral genomic, unspliced RNA (gRNA) is preferentially incorporated into assembling virions. However, a certain amount of spliced viral transcripts can also be dete
Externí odkaz:
https://doaj.org/article/321d4a057eeb4bc181e4d1d0b989ae37
Autor:
Sabine Brandt, Maik Blissenbach, Bastian Grewe, Rebecca Konietzny, Thomas Grunwald, Klaus Uberla
Publikováno v:
PLoS Pathogens, Vol 3, Iss 4, p e54 (2007)
The main function attributed to the Rev proteins of immunodeficiency viruses is the shuttling of viral RNAs containing the Rev responsive element (RRE) via the CRM-1 export pathway from the nucleus to the cytoplasm. This restricts expression of struc
Externí odkaz:
https://doaj.org/article/f4d9bb65b1074ef59c7a4c6030630c10
Autor:
Jens Bohne, Bastian Grewe, Theresa Horstkötter, Carolin Vogt, Klaus Überla, Bettina Tippler, Ralf Wagner, Bianca Müller, Han Xiao, Benedikt Asbach
Publikováno v:
Viruses, Vol 13, Iss 997, p 997 (2021)
Viruses
Volume 13
Issue 6
Viruses
Volume 13
Issue 6
Alternative splicing and the expression of intron-containing mRNAs is one hallmark of HIV gene expression. To facilitate the otherwise hampered nuclear export of non-fully processed mRNAs, HIV encodes the Rev protein, which recognizes its intronic re
Autor:
Klaus Überla, Bastian Grewe, Emanuel Wyler, Ana Beatriz Oliveira Villela Silva, Marco Thomas, Miha Milek, Florian Full, Philipp Kirchner, Arif B. Ekici, Markus Landthaler, Armin Ensser, Han Xiao, Doris Jungnickl
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
mBio
mBio
To regulate its complex splicing pattern, HIV-1 uses the adaptor protein Rev to shuttle unspliced or partially spliced mRNA from the nucleus to the cytoplasm. In the absence of Rev, these RNAs are retained in the nucleus, but it is unclear why.
Autor:
Han Xiao, Miha Milek, Klaus Überla, Emanuel Wyler, Doris Jungnickl, Ana Beatriz Oliveira Villela Silva, Markus Landthaler, Armin Ensser, Philipp Kirchner, Bastian Grewe, Arif B. Ekici
The HIV-1 Rev protein is a nuclear export factor for unspliced and incompletely-spliced HIV-1 RNAs. Without Rev, these intron-retaining RNAs are trapped in the nucleus. A genome-wide screen identified nine proteins of the spliceosome which all enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926c1485389a4bab4525777d2e176784
https://doi.org/10.1101/2020.02.04.934927
https://doi.org/10.1101/2020.02.04.934927