Výsledky vyhledávání - "Bastian Bues"

Pirfenidone affects human cardiac fibroblast proliferation and cell cycle activity in 2D cultures and engineered connective tissues

Autor: Friederike Elisabeth Ugi Meyer, Gabriela Leao Santos, Thao Phuong Doan, Alisa Nicole DeGrave, Bastian Bues, Susanne Lutz

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology.

The anti-fibrotic drug pirfenidone (PFD) is currently in clinical testing for the treatment of heart failure with preserved ejection fraction; however, its effects on human cardiac cells have not been fully investigated. Therefore, we aimed to charac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbd7a7a0c4493a2ed020472e59cc3831
https://doi.org/10.1007/s00210-023-02421-9

Zobrazit plný text záznamu

Tubular microdomains of Rab7-positive endosomes retrieve TrkA, a mechanism disrupted in Charcot–Marie–Tooth disease 2B

Autor: Lars Malte Steinbeck, Angeliki Koufali, Ronja Markworth, Vivian Dambeck, Bastian Bues, Carolin Wichmann, Tal M. Dankovich, Katja Burk

Publikováno v: Journal of Cell Science. 134

Axonal survival and growth requires signalling from tropomyosin receptor kinases (Trks). To transmit their signals, receptor–ligand complexes are endocytosed and undergo retrograde trafficking to the soma, where downstream signalling occurs. Vesicl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53167536197321a9b0c7d3a362ae8dd9
https://doi.org/10.1242/jcs.258559

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání