Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Bastian, Vögeli"'
Autor:
Andrew C. Hunt, Bastian Vögeli, Ahmed O. Hassan, Laura Guerrero, Weston Kightlinger, Danielle J. Yoesep, Antje Krüger, Madison DeWinter, Michael S. Diamond, Ashty S. Karim, Michael C. Jewett
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Antibody discovery is bottlenecked by the individual expression and evaluation of antigen-specific hits. Here, we address this bottleneck by developing a workflow combining cell-free DNA template generation, cell-free protein synthesis, and
Externí odkaz:
https://doaj.org/article/d0a62766c7bd4e69b8880f42a0cd67b4
Autor:
Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M. Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R. Kimmel, Loan Tran, Hunter Zeleznik, Steven D. Brown, Sean D. Simpson, Milan Mrksich, Ashty S. Karim, Ramon Gonzalez, Michael Köpke, Michael C. Jewett
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
An attractive route for carbon-negative synthesis of biochemical products is the reverse β-oxidation pathway coupled to the Wood-Ljungdahl pathway. Here the authors use a high-throughput in vitro prototyping workflow to screen 762 unique pathway com
Externí odkaz:
https://doaj.org/article/2db1bcf195d34b60b46738910cf4f33f
Autor:
Ari Satanowski, Beau Dronsella, Elad Noor, Bastian Vögeli, Hai He, Philipp Wichmann, Tobias J. Erb, Steffen N. Lindner, Arren Bar-Even
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Current efforts to establish synthetic carbon fixation in model heterotrophs rely on expression of heterologous enzymes. Here, the authors explore the presence and activity of a latent CO2-assimilation pathway in E. coli based only on endogenous enzy
Externí odkaz:
https://doaj.org/article/2af5c18026284ec281d826ac053f0876
Autor:
Lars Gläser, Martin Kuhl, Sofija Jovanovic, Michel Fritz, Bastian Vögeli, Tobias J. Erb, Judith Becker, Christoph Wittmann
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-13 (2020)
Abstract Background Thioesters of coenzyme A participate in 5% of all enzymatic reactions. In microbial cell factories, they function as building blocks for products of recognized commercial value, including natural products such as polyketides, poly
Externí odkaz:
https://doaj.org/article/107a004f654f4c588b797f51c8544281
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The modern cell-free protein synthesis (CFPS) system is expanding the opportunity of cell-free biomanufacturing as a versatile platform for synthesizing various therapeutic proteins. However, synthesizing human protein in the bacterial CFPS system re
Externí odkaz:
https://doaj.org/article/7768bc1e300a4fb7b0df8dc1c3b47d7d
Autor:
Hasan, DeMirci, Yashas, Rao, Gabriele M, Stoffel, Bastian, Vögeli, Kristina, Schell, Aharon, Gomez, Alexander, Batyuk, Cornelius, Gati, Raymond G, Sierra, Mark S, Hunter, E Han, Dao, Halil I, Ciftci, Brandon, Hayes, Fredric, Poitevin, Po-Nan, Li, Manat, Kaur, Kensuke, Tono, David Adrian, Saez, Samuel, Deutsch, Yasuo, Yoshikuni, Helmut, Grubmüller, Tobias J, Erb, Esteban, Vöhringer-Martinez, Soichi, Wakatsuki
Publikováno v:
ACS central science. 8(8)
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5915fda2947c222ad37cac1b99567c0
https://pubmed.ncbi.nlm.nih.gov/36032767
https://pubmed.ncbi.nlm.nih.gov/36032767
Autor:
Hasan DeMirci, Yashas Rao, Gabriele M. Stoffel, Bastian Vögeli, Kristina Schell, Aharon Gomez, Alexander Batyuk, Cornelius Gati, Raymond G. Sierra, Mark S. Hunter, E. Han Dao, Halil I. Ciftci, Brandon Hayes, Fredric Poitevin, Po-Nan Li, Manat Kaur, Kensuke Tono, David Adrian Saez, Samuel Deutsch, Yasuo Yoshikuni, Helmut Grubmüller, Tobias J. Erb, Esteban Vöhringer-Martinez, Soichi Wakatsuki
Publikováno v:
ACS central science, vol 8, iss 8
ACS Central Science
ACS Central Science
Enoyl-CoA carboxylases/reductases (ECRs) are some of the most efficient CO2-fixing enzymes described to date. However, the molecular mechanisms underlying the extraordinary catalytic activity of ECRs on the level of the protein assembly remain elusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05fa966255720bcfdf2395cc9e451cb7
https://escholarship.org/uc/item/9064b000
https://escholarship.org/uc/item/9064b000
Autor:
Jonathan W. Bogart, Maria D. Cabezas, Michael C. Jewett, Ashty S. Karim, Derek A. Wong, Bastian Vögeli
Publikováno v:
Chembiochem
Natural products and secondary metabolites comprise an indispensable resource from living organisms that have transformed areas of medicine, agriculture, and biotechnology. Recent advances in high-throughput DNA sequencing and computational analysis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de0a9f21b9439b518d898b559b186a4a
https://doi.org/10.1002/cbic.202000452
https://doi.org/10.1002/cbic.202000452
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2433
Biological systems provide a sustainable and complimentary approach to synthesizing useful chemical products. Metabolic engineers seeking to establish economically viable biosynthesis platforms strive to increase product titers, rates, and yields. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5349ec69119c14f163d9dafd5dd99ec7
https://pubmed.ncbi.nlm.nih.gov/34985746
https://pubmed.ncbi.nlm.nih.gov/34985746
Publikováno v:
Cell-Free Gene Expression ISBN: 9781071619971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d540b53f1fdb9f0b61704edd0fa97b
https://doi.org/10.1007/978-1-0716-1998-8_12
https://doi.org/10.1007/978-1-0716-1998-8_12