Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bastiaan Vliegenthart"'
Autor:
Kathleen M. Scullion, A. D. Bastiaan Vliegenthart, Laura Rivoli, Wilna Oosthuyzen, Tariq E. Farrah, Alicja Czopek, David J. Webb, Robert W. Hunter, Matthew A. Bailey, Neeraj Dhaun, James W. Dear
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101937- (2021)
Summary: Vascular and kidney dysfunction commonly co-exist. There is a need for biomarkers of vascular health. Circulating microRNAs are biomarkers; miR-126 is endothelial cell-enriched. We measured circulating miR-126 in rats with nephrotoxic nephri
Externí odkaz:
https://doaj.org/article/be8bdfd2958a4679a313fe5958f85e1c
Autor:
David M Rissin, Barbara López-Longarela, Salvatore Pernagallo, Hugh Ilyine, A D Bastiaan Vliegenthart, James W Dear, Juan J Díaz-Mochón, David C Duffy
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179669 (2017)
We have developed a single probe method for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base, and without the use of amplification by polymerases. An abasic peptide nucleic acid (PNA) p
Externí odkaz:
https://doaj.org/article/06f0f8682210475f9dba71838795e9f1
Publikováno v:
The FASEB Journal. 33
Autor:
James W. Dear, Laura Rivoli, Alicja Czopek, David J. Webb, A. D. Bastiaan Vliegenthart, Tariq E. Farrah, Matthew A. Bailey, Kathleen M. Scullion, Neeraj Dhaun, Wilna Oosthuyzen, Robert W. Hunter
Publikováno v:
Scullion, K, Vliegenthart, A D B, Rivoli, L, Oosthuyzen, W, Farrah, T, Czopek, A, Webb, D J, Hunter, R W, Bailey, M A & Dhaun, N 2021, ' Circulating argonaute-bound microRNA-126 reports vascular dysfunction and treatment response in acute and chronic kidney disease ', iScience . https://doi.org/10.1016/j.isci.2020.101937
iScience, Vol 24, Iss 1, Pp 101937-(2021)
iScience
iScience, Vol 24, Iss 1, Pp 101937-(2021)
iScience
Summary Vascular and kidney dysfunction commonly co-exist. There is a need for biomarkers of vascular health. Circulating microRNAs are biomarkers; miR-126 is endothelial cell-enriched. We measured circulating miR-126 in rats with nephrotoxic nephrit
Autor:
Peter J. Gallacher, James W. Dear, A. D. Bastiaan Vliegenthart, Tariq E. Farrah, Neeraj Dhaun, Carmelita M. J. de Potter, Job J. M. H. van Bragt, Laura Rivoli, Nikolaos Tzoumas
Publikováno v:
British Journal of Clinical Pharmacology. 83:584-592
Aim microRNA-122 (miR-122) is a hepatotoxicity biomarker with utility in the management of paracetamol overdose and in drug development. Renal dysfunction and haemodialysis have been associated with a reduction in circulating microRNA. The objective
BackgroundA biomarker that stratifies patients with complications of gallstone disease from the denominator pool of people with acute biliary-type symptoms is needed. Circulating microRNA-122 (miRNA-122), high-mobility group box1 (HMGB1), full-length
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e50b76ec65cce1615ea77ce334cb5f
https://doi.org/10.1101/189589
https://doi.org/10.1101/189589
Autor:
Anna R. Dover, James W. Dear, Catriona Clarke, Marcus J. Lyall, Robert K. Semple, A. D. Bastiaan Vliegenthart, David Church, Neeraj Dhaun, Robert W. Hunter
Publikováno v:
Church, D, Hunter, R W, Lyall, M, Clarke, C, Vliegenthart, A D B, Dear, J W, Semple, R, Dhaun, N & Dover, A R 2017, ' Resolution of hypoglycemia and cardiovascular dysfunction after rituximab treatment of insulin autoimmune syndrome ', Diabetes Care . https://doi.org/10.2337/dc17-0264
D.C. is funded by a Diabetes Research & Wellness Foundation Sutherland-Earl Clinical Fellowship (RG68554). R.W.H. is supported by the Wellcome Trust–University of Edinburgh Institutional Strategic Support Fund. N.D. is supported by a British Heart
Autor:
Salvatore Pernagallo, David M. Rissin, Hugh Ilyine, James W. Dear, David C. Duffy, A. D. Bastiaan Vliegenthart, Barbara López-Longarela, Juan J. Díaz-Mochón
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179669 (2017)
Rissin, D M, López-Longarela, B, Pernagallo, S, Ilyine, H, Vliegenthart, B, Dear, J, Díaz-Mochón, J J & Duffy, D C 2017, ' Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury ', PLoS ONE . https://doi.org/10.1371/journal.pone.0179669
Digibug. Repositorio Institucional de la Universidad de Granada
instname
PLoS ONE
Rissin, D M, López-Longarela, B, Pernagallo, S, Ilyine, H, Vliegenthart, B, Dear, J, Díaz-Mochón, J J & Duffy, D C 2017, ' Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury ', PLoS ONE . https://doi.org/10.1371/journal.pone.0179669
Digibug. Repositorio Institucional de la Universidad de Granada
instname
PLoS ONE
We have developed a single probe method for detecting microRNA from human serum using single molecule arrays, with sequence specificity down to a single base, and without the use of amplification by polymerases. An abasic peptide nucleic acid (PNA) p
Autor:
Euan A Sandilands, A. D. Bastiaan Vliegenthart, D. Nicholas Bateman, Aravindan Veiraiah, James W. Dear, Judy Coyle, Simon H. L. Thomas, Aryelly Rodriguez, Jamie G. Cooper, Isabella Butcher, David J. Webb, Michael Eddleston, Alasdair Gray, H K Ruben Thanacoody, Steff Lewis
Publikováno v:
The Lancet. 383:697-704
SummaryBackgroundParacetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interrupti
Publikováno v:
McCrae, J C, Sharkey, N, Webb, D J, Vliegenthart, A D B & Dear, J W 2016, ' Ethanol consumption produces a small increase in circulating miR-122 in healthy individuals ', Clinical Toxicology, vol. 54, no. 1, pp. 53-5 . https://doi.org/10.3109/15563650.2015.1112015
INTRODUCTION: MicroRNA 122 (miR-122) is a new circulating biomarker for liver injury, which increases earlier than conventional markers in patients with acetaminophen hepatotoxicity. However, as co-ingestion of ethanol is common with drug overdose, a