Evolution of promoter-proximal pausing enabled a new layer of transcription control.

Autor: Chivu AG; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.; Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA., Basso BA; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.; Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA., Abuhashem A; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, NY 10065, USA.; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, NY 10065, USA.; Biochemistry Cell and Molecular Biology Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, NY 10065, USA., Leger MM; Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, 08003, Spain., Barshad G; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Rice EJ; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Vill AC; Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA., Wong W; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.; Tri-Institutional training Program in Computational Biology and Medicine, New York, NY 10065, USA., Chou SP; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA., Chovatiya G; Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA., Brady R; Department of Biology, Ithaca College, Ithaca NY 14850, USA., Smith JJ; Department of Biology, University of Kentucky, Lexington, KY, 40506, USA., Wikramanayake AH; Department of Biology, University of Miami, Coral Gables, FL 33146., Arenas-Mena C; Department of Biology at the College of Staten Island and PhD Programs in Biology and Biochemistry at The Graduate Center, The City University of New York (CUNY), Staten Island, NY 10314, USA., Brito IL; Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY 14850, USA., Ruiz-Trillo I; Institute of Evolutionary Biology (CSIC-Universitat Pompeu Fabra), Barcelona, 08003, Spain.; ICREA, Pg. Lluis Companys 23, 08010 Barcelona, Spain., Barcelona, 08003, Spain., Hadjantonakis AK; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, NY 10065, USA.; Biochemistry Cell and Molecular Biology Program, Weill Cornell Graduate School of Medical Sciences, Cornell University, NY 10065, USA., Lis JT; Department of Molecular Biology & Genetics, Cornell University, Ithaca, NY 14853, USA., Lewis JJ; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.; Department of Genetics and Biochemistry, Clemson University, 105 Collings St, Clemson, SC 29634., Danko CG; Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 12. Date of Electronic Publication: 2024 Oct 12.