Alveolar type I cells can give rise to KRAS-induced lung adenocarcinoma.

Autor: Yang M; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA., Shen H; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Flodby P; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Koss MD; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Bassiouni R; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA., Liu Y; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Jashashvili T; Department of Integrative Anatomical Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Neely A; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA., Ogbolu E; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA., Castillo J; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA., Stueve TR; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA., Mullen DJ; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA., Ryan AL; Department of Anatomy and Cell Biology, Carver College of Medicine, University of Iowa, Iowa, IA 52242, USA., Carpten J; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA., Castaldi A; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Wallace WD; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Zhou B; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Southern California, Los Angeles, CA 90089, USA., Borok Z; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Marconett CN; Department of Translational Genomics, University of Southern California, Los Angeles, CA 90089, USA; Department of Surgery, University of Southern California, Los Angeles, CA 90089, USA; Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Hastings Center for Pulmonary Research, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: crystal.marconett@med.usc.edu.

Publikováno v: Cell reports [Cell Rep] 2023 Dec 26; Vol. 42 (12), pp. 113286. Date of Electronic Publication: 2023 Nov 22.

Wild-Type KRAS Allele Effects on Druggable Targets in KRAS Mutant Lung Adenocarcinomas.

Autor: Baldelli E; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., El Gazzah E; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, George Mason University, Manassas, VA 20110, USA., Moran JC; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Hodge KA; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Manojlovic Z; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Bassiouni R; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Carpten JD; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Ludovini V; Division of Medical Oncology, S. Maria della Misericordia Hospital, 06156 Perugia, Italy., Baglivo S; Division of Medical Oncology, S. Maria della Misericordia Hospital, 06156 Perugia, Italy., Crinò L; Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, 47014 Meldola, Italy., Bianconi F; Independent Researcher, Belvedere 44, Montefalco, 06036 Perugia, Italy., Dong T; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Loffredo J; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Petricoin EF; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Pierobon M; Center for Applied Proteomics & Molecular Medicine, George Mason University, Manassas, VA 20110, USA.; School of Systems Biology, George Mason University, Manassas, VA 20110, USA.

Publikováno v: Genes [Genes (Basel)] 2021 Sep 11; Vol. 12 (9). Date of Electronic Publication: 2021 Sep 11.

Applicability of spatial transcriptional profiling to cancer research.

Autor: Bassiouni R; Department of Translational Genomics, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, USA., Gibbs LD; Department of Translational Genomics, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, USA., Craig DW; Department of Translational Genomics, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, USA., Carpten JD; Department of Translational Genomics, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, USA., McEachron TA; Department of Translational Genomics, Keck School of Medicine, University of Southern California, 1450 Biggy Street, Los Angeles, CA 90033, USA; Pediatric Oncology Branch, National Cancer Institute, 10 Center Drive, Bethesda, MD 20892, USA. Electronic address: troy.mceachron@nih.gov.

Publikováno v: Molecular cell [Mol Cell] 2021 Apr 15; Vol. 81 (8), pp. 1631-1639. Date of Electronic Publication: 2021 Apr 06.

Tumor necrosis factor receptor 2 promotes endothelial cell-mediated suppression of CD8+ T cells through tuning glycolysis in chemoresistance of breast cancer.

Autor: Hu, Yu¹ (AUTHOR), Lou, Xiaohan¹ (AUTHOR), Zhang, Kaili¹ (AUTHOR), Pan, Longze^1,2 (AUTHOR), Bai, Yueyue^1,3 (AUTHOR), Wang, Linlin¹ (AUTHOR), Wang, Ming¹ (AUTHOR), Yan, Yan¹ (AUTHOR), Wan, Jiajia¹ (AUTHOR), Yao, Xiaohan¹ (AUTHOR), Duan, Xixi¹ (AUTHOR), Ni, Chen¹ (AUTHOR) nichen904@163.com, Qin, Zhihai¹ (AUTHOR) zhihai@ibp.ac.cn

Publikováno v: Journal of Translational Medicine. 7/20/2024, Vol. 22 Issue 1, p1-22. 22p.

Identification of De Novo and Rare Inherited Copy Number Variants in Children with Syndromic Congenital Heart Defects.

Autor: Hussein IR; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia. irhussein@gmail.com., Bader RS; Pediatric Cardiology Department, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia., Chaudhary AG; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia.; Faculty of Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Bassiouni R; Children Hospital, Ministry of Health, Ta'if, Kingdom of Saudi Arabia., Alquaiti M; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia., Ashgan F; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia., Schulten HJ; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia., Al Qahtani MH; Centre of Excellence in Genomic Medicine Research (CEGMR), King Fahd Medical Research Centre, King Abdulaziz University, Jeddah, 21589, Kingdom of Saudi Arabia.; Faculty of Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.

Publikováno v: Pediatric cardiology [Pediatr Cardiol] 2018 Jun; Vol. 39 (5), pp. 924-940. Date of Electronic Publication: 2018 Mar 14.