Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Bassem M Mohammed"'
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 7, Pp n/a-n/a (2022)
Abstract A State of the Art lecture titled “Cryo‐EM structures of coagulation factors” was presented at the ISTH Congress in 2022. Cryogenic electron microscopy (cryo‐EM) is a revolutionary technique capable of solving the structure of high m
Externí odkaz:
https://doaj.org/article/9bf0407086324aaf8c9481a3d6fa9262
Publikováno v:
Platelets, Vol 31, Iss 4, Pp 417-422 (2020)
Hemostasis is the normal process that produces a blood clot at a site of vascular injury. Mice are widely used to study hemostasis and abnormalities of blood coagulation because their hemostatic system is similar in most respects to that of humans, a
Externí odkaz:
https://doaj.org/article/ca5571e14903401283fc39f6f97c73a1
Autor:
Wen Su, Sin Fun Sia, Aaron J. Schmitz, Traci L. Bricker, Tyler N. Starr, Allison J. Greaney, Jackson S. Turner, Bassem M. Mohammed, Zhuoming Liu, Ka Tim Choy, Tamarand L. Darling, Astha Joshi, Ka Man Cheng, Alvina Y. L. Wong, Houda H. Harastani, John M. Nicholls, Sean P. J. Whelan, Jesse D. Bloom, Hui-Ling Yen, Ali H. Ellebedy, Adrianus C. M. Boon
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is the main target for neutralizing antibodies. These antibodies can be elicited through immunization or passively transferred as therapeutics in the form of convalescent-
Externí odkaz:
https://doaj.org/article/59017aa8fbfc49cca3569388d8d7b51e
Autor:
Daniel Contaifer, Jr., Daniel E. Carl, Urszula Osinska Warncke, Erika J. Martin, Bassem M. Mohammed, Benjamin Van Tassell, Donald F. Brophy, Charles E. Chalfant, Dayanjan S. Wijesinghe
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 3, Pp 586-599 (2017)
Hemodialysis (HD) and peritoneal dialysis (PD) are the primary means of managing end stage renal disease (ESRD). However, these treatment modalities are associated with the onset of coagulation abnormalities. Effective management of coagulation risk
Externí odkaz:
https://doaj.org/article/802bf30a12c84747b2f2c7abb81d1889
Publikováno v:
Blood.
Coagulation factor V (fV) is the inactive precursor of fVa, an essential component of the prothrombinase complex required for rapid activation of prothrombin in the penultimate step of the coagulation cascade. In addition, fV regulates the tissue fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e61834e980219834f79bbcd183b53e3f
https://doi.org/10.1182/blood.2022019486
https://doi.org/10.1182/blood.2022019486
Autor:
S. Kent Dickeson, Sunil Kumar, Mao-Fu Sun, Bassem M. Mohammed, Dennis R. Phillips, James C. Whisstock, Adam J. Quek, Edward P. Feener, Ruby H. P. Law, David Gailani
Publikováno v:
Blood
Patients with hereditary angioedema (HAE) experience episodes of bradykinin (BK)-induced swelling of skin and mucosal membranes. The most common cause is reduced plasma activity of C1 inhibitor, the main regulator of the proteases plasma kallikrein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fb565810b9d00d51524469e20cd25d
https://europepmc.org/articles/PMC9074402/
https://europepmc.org/articles/PMC9074402/
Autor:
Ramesh Natarajan, Alpha A. Fowler, Daniela Farkas, Donald F. Brophy, Bernard J. Fisher, Donatas Kraskauskas, Bassem M. Mohammed
Publikováno v:
Nutrients, Vol 5, Iss 8, Pp 3131-3150 (2013)
Introduction: Neutrophil extracellular trap (NET) formation was recently identified as a novel mechanism to kill pathogens. However, excessive NET formation in sepsis can injure host tissues. We have recently shown that parenteral vitamin C (VitC) is
Externí odkaz:
https://doaj.org/article/18ade23810554889af231d9d5515dcb4
Autor:
Qiufang Cheng, Bassem M Mohammed, David Gailani, Anton Matafonov, Mao-fu Sun, Ingrid M. Verhamme, Kusumam Joseph, Allen P. Kaplan, Ivan B. Ivanov, S. Kent Dickeson
Publikováno v:
Blood. 135:558-567
Prekallikrein (PK) is the precursor of the trypsin-like plasma protease kallikrein (PKa), which cleaves kininogens to release bradykinin and converts the protease precursor factor XII (FXII) to the enzyme FXIIa. PK and FXII undergo reciprocal convers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702640eaddc9e73c2250376d1de584fb
https://doi.org/10.1182/blood.2019002224
https://doi.org/10.1182/blood.2019002224
Autor:
Donald F. Brophy, Rami A. Al-Horani, Masahiro Sakagami, Elsamani I. Abdelfadiel, Erika J. Martin, Daniel K. Afosah, Bassem M. Mohammed, Shravan Morla, Umesh R. Desai, Jyothi C. Sistla
Publikováno v:
J Thromb Haemost
Background Human factor XIa (FXIa) is an actively pursued target for development of safer anticoagulants. Our long-standing hypothesis has been that allosterism originating from heparin-binding site(s) on coagulation enzymes is a promising approach t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f011456ef4503dfc3f7422b82d5f88e
https://doi.org/10.1111/jth.14606
https://doi.org/10.1111/jth.14606
Autor:
Sin Fun Sia, Bassem M. Mohammed, Jackson S. Turner, Sean P. J. Whelan, Zhuoming Liu, Ka Man Cheng, Wen Su, Jesse D. Bloom, Tamarand L. Darling, Astha Joshi, Hui-Ling Yen, Traci L. Bricker, Alvina Y L Wong, Adrianus C. M. Boon, Allison J. Greaney, Houda H. Harastani, Aaron J. Schmitz, Tyler N. Starr, Ali H. Ellebedy, John M. Nicholls, Ka Tim Choy
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is the main target for neutralizing antibodies. These antibodies can be elicited through immunization or passively transferred as therapeutics in the form of convalescent-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3860d58e9841a19f8b4d1e6c1f83199c
https://doi.org/10.1128/mbio.02395-21
https://doi.org/10.1128/mbio.02395-21