Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Bassem, A Hassan"'
Publikováno v:
Bio-Protocol, Vol 13, Iss 21 (2023)
Visual learning in animals is a remarkable cognitive ability that plays a crucial role in their survival and adaptation. Therefore, the ability to learn is highly conserved among animals. Despite lacking a centralized nervous system like vertebrates,
Externí odkaz:
https://doaj.org/article/1dd836fd9e39445bb8ac8868c06bac70
Autor:
Emeric Merour, Hatem Hmidan, Corentine Marie, Pierre-Henri Helou, Haiyang Lu, Antoine Potel, Jean-Baptiste Hure, Adrien Clavairoly, Yi Ping Shih, Salman Goudarzi, Sebastien Dussaud, Philippe Ravassard, Sassan Hafizi, Su Hao Lo, Bassem A Hassan, Carlos Parras
Publikováno v:
eLife, Vol 11 (2022)
The differentiation of oligodendroglia from oligodendrocyte precursor cells (OPCs) to complex and extensive myelinating oligodendrocytes (OLs) is a multistep process that involves large-scale morphological changes with significant strain on the cytos
Externí odkaz:
https://doaj.org/article/c032f3eb47ba4b0586ac73356e196c31
Autor:
Ferdi Ridvan Kiral, Gerit Arne Linneweber, Thomas Mathejczyk, Svilen Veselinov Georgiev, Mathias F. Wernet, Bassem A. Hassan, Max von Kleist, Peter Robin Hiesinger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The molecular mechanisms that restrict synapse formation with incorrect partners remain unclear. Here, authors use 4D imaging in developing Drosophila brains to show that filopodial kinetics are regulated by autophagy and this restricts inappropriate
Externí odkaz:
https://doaj.org/article/7dd26b1025524b628b2b4f76849c0554
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100760- (2021)
Summary: The architecturally stereotypical structure of cerebellum is ideal for investigating the generation of neuronal diversity, but in vitro models for assessing early cerebellar progenitor differentiation were lacking. Here, we report a detailed
Externí odkaz:
https://doaj.org/article/de649b65eda44a939b4952244898517d
Autor:
Tengyuan Liu, Tingting Zhang, Maya Nicolas, Lydie Boussicault, Heather Rice, Alessia Soldano, Annelies Claeys, Iveta Petrova, Lee Fradkin, Bart De Strooper, Marie-Claude Potier, Bassem A Hassan
Publikováno v:
eLife, Vol 10 (2021)
The Amyloid Precursor Protein (APP) and its homologues are transmembrane proteins required for various aspects of neuronal development and activity, whose molecular function is unknown. Specifically, it is unclear whether APP acts as a receptor, and
Externí odkaz:
https://doaj.org/article/607c0b2d232a4420988219f23b50a620
Publikováno v:
JSES Reviews, Reports, and Techniques. 3:160-165
Autor:
Pablo Guzmán-Palma, Esteban G. Contreras, Natalia Mora, Macarena Smith, M. Constanza González-Ramírez, Jorge M. Campusano, Jimena Sierralta, Bassem A. Hassan, Carlos Oliva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Neurogenesis is achieved through a sequence of steps that include specification and differentiation of progenitors into mature neurons. Frequently, precursors migrate to distinct positions before terminal differentiation. The Slit-Robo pathway, forme
Externí odkaz:
https://doaj.org/article/ba1572b36c824e9e845a54a0ab854b1b
Autor:
Irini A Kessissoglou, Dominique Langui, Amr Hasan, Maral Maral, Suchetana B Dutta, Peter Robin Hiesinger, Bassem A Hassan
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000703 (2020)
The amyloid precursor protein (APP) is a structurally and functionally conserved transmembrane protein whose physiological role in adult brain function and health is still unclear. Because mutations in APP cause familial Alzheimer's disease (fAD), mo
Externí odkaz:
https://doaj.org/article/d38998b53b704769a887227f7274d833
Autor:
Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E. de Bock, Olga Gielen, Mardelle Atkins, Jiekun Yan, Georg Halder, Bassem A. Hassan, Jan Cools
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-16 (2018)
Abstract Background The CNOT3 protein is a subunit of the CCR4-NOT complex, which is involved in mRNA degradation. We recently identified CNOT3 loss-of-function mutations in patients with T-cell acute lymphoblastic leukemia (T-ALL). Methods Here, we
Externí odkaz:
https://doaj.org/article/d2b4f3970332452b81f7d13001aa3d14
Autor:
Giovanni Morelli, Aviel Even, Ivan Gladwyn-Ng, Romain Le Bail, Michal Shilian, Juliette D. Godin, Elise Peyre, Bassem A. Hassan, Arnaud Besson, Jean-Michel Rigo, Miguel Weil, Bert Brône, Laurent Nguyen
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2429-2442 (2018)
Summary: The protein p27Kip1 plays roles that extend beyond cell-cycle regulation during cerebral cortex development, such as the regulation of neuronal migration and neurite branching via signaling pathways that converge on the actin and microtubule
Externí odkaz:
https://doaj.org/article/378b315858594c00bfd8aedf11284e49