Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Bassam M Elmadhoun"'
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 15, Iss 3 (2012)
Purpose: The extent of palmitate uptake by hepatocytes is dependent upon the surface charge of the extracellular binding protein. Specifically, hepatocyte uptake is greater when palmitate is bound to cationic binding proteins than when it is bound to
Externí odkaz:
https://doaj.org/article/92fb3e77ce2f4ee9877c31e4d1bf373e
Autor:
Daniel Y. Hung, Frank J. Burczynski, Ping Chang, Michael S. Roberts, Andrew L. Lewis, Gopalan Rajaraman, Guqi Wang, Bassam M. Elmadhoun
Publikováno v:
Molecular and Cellular Biochemistry. 270:115-124
Understanding the driving forces for the hepatic uptake of endogenous and exogenous substrates in isolated cells and organs is fundamental to describing the underlying hepatic physiology/pharmacology. In this study we investigated whether uptake of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de623147fbaa79e617dd59952040a7a2
https://doi.org/10.1007/s11010-005-5267-2
https://doi.org/10.1007/s11010-005-5267-2
Publikováno v:
European Journal of Biochemistry. 268:3145-3153
The role of extracellular binding proteins in the rate of [3H]palmitate uptake by neonatal cardiac myocytes and hepatocytes was investigated using a model-independent approach. Binding proteins used in this study included alpha1-acid glycoprotein [is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a9cb1a1e433ebaa62fffae1ff7f8e6
https://doi.org/10.1046/j.1432-1327.2001.02190.x
https://doi.org/10.1046/j.1432-1327.2001.02190.x
Autor:
Frank J. Burczynski, Bassam M. Elmadhoun, Michael S. Roberts, Kenneth G. Standing, Y M She, Guqi Wang
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 79:868-875
The role of plasma proteins on the cellular uptake of lipophilic substrates has perplexed investigators for many years. We tested the hypothesis that an ionic interaction between the protein-ligand complex and hepatocyte surface may be responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82056bf93743a633090809b4a56c0179
https://doi.org/10.1139/cjpp-79-10-868
https://doi.org/10.1139/cjpp-79-10-868
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 275:G638-G644
Determination of the BSA-palmitate high-affinity binding constant ( Ka) traditionally relied on the heptane-water partitioning technique. We used this technique to calculate Kafor the BSA-[3H]palmitate complex, to determine if Kawas independent of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f228b5adff4da42436f3b3540f8ac6
https://doi.org/10.1152/ajpgi.1998.275.4.g638
https://doi.org/10.1152/ajpgi.1998.275.4.g638
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 15, Iss 3 (2012)
Purpose: The extent of palmitate uptake by hepatocytes is dependent upon the surface charge of the extracellular binding protein. Specifically, hepatocyte uptake is greater when palmitate is bound to cationic binding proteins than when it is bound to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39988f4532cc3c07e837c003ee8681dc
https://doi.org/10.18433/j3bc8w
https://doi.org/10.18433/j3bc8w