Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Basmeleh A"'
Autor:
Abdul Latip, Siti Musa’adah, Herdianto Wahyu Pratomo, Resa Septian Aditya, Abdul Munim Al Basmeleh
Publikováno v:
Paedagoria, Vol 15, Iss 2, Pp 255-262 (2024)
Abstrak: Media berbasis game edukasi mengalami perkembangan sebagai respon terhadap adanya perubahan tantangan dan kebutuhan dalam proses pembelajaran. Tujuan penelitian ini melakukan analisis dan pemetaan mengenai media berbasis game edukasi dalam p
Externí odkaz:
https://doaj.org/article/24529b2350ae41d3a43a37144235694d
Autor:
Cecile Geuijen, Paul Tacken, Liang-Chuan Wang, Rinse Klooster, Pieter Fokko van Loo, Jing Zhou, Arpita Mondal, Yao-bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda J. A. Hendriks, Hans van der Maaden, Eric Rovers, Steef Engels, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Wilfred Marissen, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Soyeon Kim, Marina Martinez, Shaun O’Brien, Edmund Moon, Steven Albelda, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Alexander B. H. Bakker, Peggy Scherle, Ton Logtenberg, Gregory Hollis, John de Kruif, Reid Huber, Patrick A. Mayes, Mark Throsby
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The anti-tumour effect of immune checkpoint inhibitors is potentiated by CD137 agonists in preclinical models, but translation of these results to the clinical practice is hampered by toxicity. Authors describe here a human CD137xPD-L1 bispecific ant
Externí odkaz:
https://doaj.org/article/4044cbbb9c1d4937ac08f857eba69b30
Autor:
Jing Zhou, Mark Throsby, Lex Bakker, Arpita Mondal, Wilfred Marissen, Paul Tacken, Steef Engels, Liang-Chuan Wang, Patrick Mayes, Cecile Geuijen, Rinse Klooster, Pieter Fokko Van Loo, Yao-Bin Liu, Arjen Kramer, Thomas Condamine, Alla Volgina, Linda Hendriks, Hans van der Maaden, Eric Rovers, Floris Fransen, Renate den Blanken-Smit, Vanessa Zondag-van der Zande, Abdul Basmeleh, Willem Bartelink, Ashwini Kulkarni, Cheng-Yen Huang, Leslie Hall, Shane Harvey, Chrysi Kanellopoulou, Shaun Stewart, Horacio Nastri, Ton Logtenberg, Simon Plyte
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
Autor:
Bram Herpers, Berina Eppink, Mark I. James, Carme Cortina, Adrià Cañellas-Socias, Sylvia F. Boj, Xavier Hernando-Momblona, Dominik Glodzik, Rob C. Roovers, Marc van de Wetering, Carina Bartelink-Clements, Vanessa Zondag-van der Zande, Jara García Mateos, Kuan Yan, Lucia Salinaro, Abdul Basmeleh, Szabolcs Fatrai, David Maussang, Jeroen J. Lammerts van Bueren, Irene Chicote, Garazi Serna, Laia Cabellos, Lorena Ramírez, Paolo Nuciforo, Ramon Salazar, Cristina Santos, Alberto Villanueva, Camille Stephan-Otto Attolini, Elena Sancho, Hector G. Palmer, Josep Tabernero, Michael R. Stratton, John de Kruif, Ton Logtenberg, Hans Clevers, Leo S. Price, Robert G. J. Vries, Eduard Batlle, Mark Throsby
Publikováno v:
Nature cancer, 3(4), 418-436
Patient-derived organoids (PDOs) recapitulate tumor architecture, contain cancer stem cells and have predictive value supporting personalized medicine. Here we describe a large-scale functional screen of dual-targeting bispecific antibodies (bAbs) on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6787d32a1a24821ce4603c0851f3e6
https://pure.knaw.nl/portal/en/publications/06b7bea9-adb4-44dc-9013-631489b16e6a
https://pure.knaw.nl/portal/en/publications/06b7bea9-adb4-44dc-9013-631489b16e6a
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Steven M. Albelda, Steef Engels, Soyeon Kim, Alla Volgina, Floris Fransen, Linda Johanna Aleida Hendriks, Cecile Geuijen, Shane Harvey, Horacio Nastri, Reid Huber, Leslie Hall, Gregory Hollis, John de Kruif, Jing Zhou, Abdul Basmeleh, Pieter Fokko Van Loo, Mark Throsby, Edmund K. Moon, Arjen Kramer, Willem Bartelink, Eric Rovers, Paul Tacken, Hans van der Maaden, Vanessa Zondag-van der Zande, Cheng Yen Huang, Rinse Klooster, Liang Chuan Wang, Ashwini Kulkarni, Chrysi Kanellopoulou, Marina Martinez, Wilfred E. Marissen, Shaun O'Brien, Alexander Berthold Hendrik Bakker, Ton Logtenberg, Renate den Blanken-Smit, Shaun Stewart, Peggy Scherle, Arpita Mondal, Patrick Mayes, Yao bin Liu, Thomas Condamine
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Immune checkpoint inhibitors demonstrate clinical activity in many tumor types, however, only a fraction of patients benefit. Combining CD137 agonists with these inhibitors increases anti-tumor activity preclinically, but attempts to translate these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69ccb4c8aa2845dfcef907bf76c0bc4
http://europepmc.org/articles/PMC8295259
http://europepmc.org/articles/PMC8295259
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Cecile Geuijen, Floris Fransen, Renate den Blanken-Smit, Ton Logtenberg, Vanessa Zondag-van der Zande, Thomas Condamine, Arjen Kramer, Willem Bartelink, Mark Throsby, Pieter Fokko Van Loo, Liang-Chuan Wang, Yao-Bin Liu, Ashwini Kulkarni, Chrysi Kanellopoulou, Rinse Klooster, Simon Plyte, Wilfred E. Marissen, Linda Johanna Aleida Hendriks, Arpita Mondal, Abdul Basmeleh, Shane Harvey, Lex Bakker, Leslie Hall, Jing Zhou, Paul Tacken, Eric Rovers, Hans van der Maaden, Steef Engels, Shaun Stewart, Patrick Mayes, Cheng-Yen Huang, Alla Volgina, Horacio Nastri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background MCLA-145 is a CD137 x PD-L1 bispecific antibody that releases PD-L1 mediated T-cell inhibition and activates and expands T cells through agonism of CD137. Immune checkpoint inhibitors (ICI) against PD-(L)1 have demonstrated anti-tumor effi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1182175d9e81f991933499ca20ee001a
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
https://doaj.org/article/3ac9962628b4422ba42992da2d11038e
Autor:
Abdul Basmeleh, Cecile Geuijen, Patrick Mayes, Paul Tacken, Linda Kaldenberg-Hendriks, Willem Bartelink, Gregory Hollis, Jing Zhou, Cheng-Yen Huang, John de Kruif, Rinse Klooster, Steve Wang, Arjen Kramer, Reid Huber, Mark Throsby, Renate den Blanken-Smit, Shaun Stewart, Horacio Nastri, Vanessa Zondag-van de Zande
Publikováno v:
Cancer Research. 79:541-541
CD137 (4-1BB) is a transmembrane costimulatory receptor on T and NK cells that enhances adaptive immune responses and is a critical mediator of antitumor immunity. CD137 signaling requires receptor clustering normally facilitated by the trimeric CD13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4d758db9ed03508d8c09a388d6875d
https://doi.org/10.1158/1538-7445.am2019-541
https://doi.org/10.1158/1538-7445.am2019-541
Publikováno v:
mAbs. 4:740-752
The presence of protein aggregates in biopharmaceutical formulations is of great concern for safety and efficacy reasons. The aim of this study was to correlate the type and amount of IgG monoclonal antibody aggregates with their immunogenic potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c18610844b2f278cd9dc010ed8bb827
https://doi.org/10.4161/mabs.22066
https://doi.org/10.4161/mabs.22066