Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Basma F. Benabdallah"'
Autor:
Manaf Bouchentouf, Basma F. Benabdallah, Marcel Dumont, Joel Rousseau, Luc Jobin, Jacques P. Tremblay
Publikováno v:
BioTechniques, Vol 38, Iss 6, Pp 937-942 (2005)
The quantification of the graft success is a key element to evaluate the efficiency of cellular therapies for several pathologies such as Duchenne muscular dystrophy. This study describes an approach to evaluate the success of myoblast transplantatio
Externí odkaz:
https://doaj.org/article/c3f87727caca429fb54d6061d5bc8f0f
Autor:
Basma F. Benabdallah, Manaf Bouchentouf, Joel Rousseau, Pascal Bigey, Annick Michaud, Pierre Chapdelaine, Daniel Scherman, Jacques P. Tremblay
Publikováno v:
Cell Transplantation, Vol 17 (2008)
Duchenne muscular dystrophy is a recessive disease due to a mutation in the dystrophin gene. Myoblast transplantation permits to introduce the dystrophin gene in dystrophic muscle fibers. However, the success of this approach is reduced by the short
Externí odkaz:
https://doaj.org/article/c9dd9d025deb409e85d09370d064785f
Autor:
Jacques P. Tremblay, Basma F. Benabdallah, Elie Haddad, Chantale Maltais, Cynthia Désaulniers-Langevin, Marie-Lyn Goyer, Chloé Colas, Yuanyi Li, Christian Beauséjour, Jean V. Guimond
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 267-277 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
It is still unclear if immune responses will compromise the large‐scale utilization of human induced pluripotent stem cells (hiPSCs)‐derived cell therapies. To answer this question, we used humanized mouse models generated by the adoptive transfe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65682629cb24b7c425648129f84e8ae9
https://doi.org/10.1002/sctm.19-0452
https://doi.org/10.1002/sctm.19-0452
Autor:
Dorothée Dal Soglio, Damien Maggiorani, Yuanyi Li, Benjamin Ellezam, Chloé Colas, Massimiliano Paganelli, Basma F. Benabdallah, Gaël Moquin-Beaudry, Elie Haddad, Marie-Agnès M’Callum, Jean V. Guimond, Claudia Raggi, Christian Beauséjour, Oanh Le
Modeling the tumor-immune cell interactions in humanized mice is complex and limits drug development. Here, we generated easily accessible tumor models by transforming either primary skin fibroblasts or iPSC-derived cell lines injected in immune-defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd291d458552ccbe908a17788857d3f3
https://doi.org/10.1101/2021.04.02.437733
https://doi.org/10.1101/2021.04.02.437733
Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation
Autor:
Basma F Benabdallah, Arnaud Duval, Joel Rousseau, Pierre Chapdelaine, Michael C Holmes, Eli Haddad, Jacques P Tremblay, Christian M Beauséjour
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Zinc finger nucleases (ZFN) can facilitate targeted gene addition to the genome while minimizing the risks of insertional mutagenesis. Here, we used a previously characterized ZFN pair targeting the chemokine (C-C motif) receptor 5 (CCR5) locus to in
Externí odkaz:
https://doaj.org/article/e8fb86ffdb2b4df4a98130eb82357c3b
Autor:
Jean V. Guimont, Yuanyi Li, Chloé Colas, Chantale Maltais, Christian Beauséjour, Basma F. Benabdallah, Cynthia Désaulniers-Langevin, Elie Haddad, Marie-Lyn Goyer, Jacques P. Tremblay
It is still unclear if immune responses will compromise the large scale utilization of cell therapies derived from human induced pluripotent stem cells (hiPSCs). To answer this question, we used humanized mouse models generated by the adoptive transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448fba22b554faf6b91a1feb64194ef6
Autor:
Daniel Scherman, M. Bouchentouf, Jacques P. Tremblay, Pascal Bigey, Basma F. Benabdallah, T M Yau
Publikováno v:
Gene Therapy. 15:404-414
Muscle precursor cell (myoblasts) transplantation is considered as a potential approach to restore dystrophin expression in Duchenne muscular dystrophy (DMD) patients. The study purpose was to verify the implication of hypoxia in the myoblast death o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4c8a85aac706ee6e79f3d98a820748
https://doi.org/10.1038/sj.gt.3303059
https://doi.org/10.1038/sj.gt.3303059
Autor:
Elmostafa El Fahime, Philippe Mills, Jacques P. Tremblay, Basma F. Benabdallah, J.F. Lafreniere
Publikováno v:
Experimental Cell Research. 313:527-537
Duchenne muscular dystrophy (DMD) is an inherited disease that leads to progressive muscle wasting. Myogenic precursor cell transplantation is an approach that can introduce the normal dystrophin gene in the muscle fibers of the patients. Unfortunate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::befef3c7907580b7b7fb04e767b6dd20
https://doi.org/10.1016/j.yexcr.2006.10.032
https://doi.org/10.1016/j.yexcr.2006.10.032
Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation
Autor:
Pierre Chapdelaine, Eli Haddad, Joël Rousseau, Arnaud Duval, Jacques P. Tremblay, Michael C. Holmes, Christian Beauséjour, Basma F. Benabdallah
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
Zinc finger nucleases (ZFN) can facilitate targeted gene addition to the genome while minimizing the risks of insertional mutagenesis. Here, we used a previously characterized ZFN pair targeting the chemokine (C-C motif) receptor 5 (CCR5) locus to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeebaa134a6fca0d97e51a8c77fbb1da
https://pubmed.ncbi.nlm.nih.gov/23360951
https://pubmed.ncbi.nlm.nih.gov/23360951
Autor:
Basma F. Benabdallah, Oanh Le, Audrey Fortin, Christian Beauséjour, Palacio Lg, Elie Haddad, Cynthia L. Carbonneau
The relative ineffectiveness of hematopoietic stem cells in reaching the bone marrow upon transplantation combined with the limited number of these cells available is a major reason for graft failure and delayed hematopoietic recovery. Hence, the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dee143e5cc2a9776a4537a863d2ea7
https://europepmc.org/articles/PMC3585478/
https://europepmc.org/articles/PMC3585478/