Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Basile Siewe"'
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
In autoimmune diseases, toll-like receptor (TLR)-stimulated pro-inflammatory IL-6-secreting B cells exert pathogenic roles. Similarly, B cell Fc receptor-like 4 (FcRL4) expression amplifies TLR stimulation, and in rheumatoid arthritis patients, FcRL4
Externí odkaz:
https://doaj.org/article/53865ca37f5e47bb9f9a563749b9d6c8
Autor:
Sergio Serrano-Villar, Talia Sainz, Zhong-Min Ma, Netanya S Utay, Tae Wook-Chun, Surinder Mann, Angela D Kashuba, Basile Siewe, Anthony Albanese, Paolo Troia-Cancio, Elizabeth Sinclair, Anoma Somasunderam, Tammy Yotter, Steven G Deeks, Alan Landay, Richard B Pollard, Christopher J Miller, Santiago Moreno, David M Asmuth
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006368 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1005381.].
Externí odkaz:
https://doaj.org/article/b4a1aa6644d042a4b9efefd5e7c4b9ac
Autor:
Sergio Serrano-Villar, Talia Sainz, Zhong-Min Ma, Netanya S Utay, Tae-Wook Chun, Surinder Mann, Angela D Kashuba, Basile Siewe, Anthony Albanese, Paolo Troia-Cancio, Elizabeth Sinclair, Anoma Somasunderam, Tammy Yotter, Steven G Deeks, Alan Landay, Richard B Pollard, Christopher J Miller, Santiago Moreno, David M Asmuth
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005540 (2016)
Externí odkaz:
https://doaj.org/article/a6ef1c1428e54acb94946b04ab45ba3c
Autor:
Sergio Serrano-Villar, Talia Sainz, Zhong-Min Ma, Netanya S Utay, Tae-Wook Chun, Surinder Mann, Angela D Kashuba, Basile Siewe, Anthony Albanese, Paolo Troia-Cancio, Elizabeth Sinclair, Anoma Somasunderam, Tammy Yotter, Steven G Deeks, Alan Landay, Richard B Pollard, Christopher J Miller, Santiago Moreno, David M Asmuth
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005381 (2016)
Whether initiation of antiretroviral therapy (ART) regimens aimed at achieving greater concentrations within gut associated lymphoid tissue (GALT) impacts the level of mucosal immune reconstitution, inflammatory markers and the viral reservoir remain
Externí odkaz:
https://doaj.org/article/4c8ddb8fc36e4a4592983eaa38e14cda
Autor:
Ece A Mutlu, Ali Keshavarzian, John Losurdo, Garth Swanson, Basile Siewe, Christopher Forsyth, Audrey French, Patricia Demarais, Yan Sun, Lars Koenig, Stephen Cox, Phillip Engen, Prachi Chakradeo, Rawan Abbasi, Annika Gorenz, Charles Burns, Alan Landay
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003829 (2014)
HIV progression is characterized by immune activation and microbial translocation. One factor that may be contributing to HIV progression could be a dysbiotic microbiome. We therefore hypothesized that the GI mucosal microbiome is altered in HIV pati
Externí odkaz:
https://doaj.org/article/b278e4d3aab749f084c6a546c9f3fe8e
Autor:
Basile Siewe, Jennillee Wallace, Sonya Rygielski, Jack T Stapleton, Jeffrey Martin, Steven G Deeks, Alan Landay
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e92934 (2014)
During HIV infection, IL-10/IL-10 receptor and programmed death-1 (PD-1)/programmed death-1-ligand (PD-L1) interactions have been implicated in the impairment of cytotoxic T lymphocyte (CTL) activity. Despite antiretroviral therapy (ART), attenuated
Externí odkaz:
https://doaj.org/article/94d95f5fba7e41b48cd10833ad9e7309
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Klaus Kaluza, Sebastian Breuer, Roland Buelow, Grit Zarnt, Nicole Schueler, Valeria Lifke, Basile Siewe, Alain Tissot, Irmgard Thorey, Stefan Lorenz, Dominique Ostler, Josef Platzer, Brigitte Kaluza, Francesca Ros, Juergen Puels, Tajana Dragicevic, Sonja Offner, Imke Hansen-Wester, Stefan Klostermann, Helmut Niersbach, Wim Van Schooten
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Autor:
Sara Gianella, Cassandra V. Kotter, Charles E. Robertson, Alan L. Landay, Davey M. Smith, Basile Siewe, Gregory L. Austin, McCarter, McManus Mc, Cara C. Wilson, Daniel N. Frank, Eric J. Lee, Stephanie M. Dillon
Publikováno v:
Mucosal immunology
HIV-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. Dendritic cells (DCs) are crucial in maintaining intestinal homeostasis, but the impact of HIV-1 infection on intestin