Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Basile Pérès"'
Autor:
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V. Ambudkar, Marcel I. Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1259 (2023)
Inhibition of ABC transporters is a promising approach to overcome multidrug resistance in cancer. Herein, we report the characterization of a potent ABCG2 inhibitor, namely, chromone 4a (C4a). Molecular docking and in vitro assays using ABCG2 and P-
Externí odkaz:
https://doaj.org/article/7e41a2636a89473abced9f9c7c0145b8
Autor:
Céline Dard, Baptiste Leforestier, Flaviane Francisco Hilário, Mohamed Dit Mady Traoré, Marie-Ange Lespinasse, Basile Pérès, Marie-Carmen Molina, Rossimiriam Pereira de Freitas, Anne Milet, Danièle Maubon, Yung-Sing Wong
Publikováno v:
Molecules, Vol 26, Iss 24, p 7506 (2021)
FR235222 is a natural tetra-cyclopeptide with a strong inhibition effect on histone deacetylases, effective on mammalian cells as well as on intracellular apicomplexan parasites, such as Toxoplasma gondii, in the tachyzoite and bradyzoite stages. Thi
Externí odkaz:
https://doaj.org/article/03e13df129484c049ed0ae665f8d8792
Autor:
Brayan Roulier, Inbal Rush, Leticia M. Lazinski, Basile Pérès, Hamza Olleik, Guy Royal, Ayelet Fishman, Marc Maresca, Romain Haudecoeur
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2023, 246, pp.114972. ⟨10.1016/j.ejmech.2022.114972⟩
European Journal of Medicinal Chemistry, 2023, 246, pp.114972. ⟨10.1016/j.ejmech.2022.114972⟩
International audience; Human tyrosinase (hsTYR) catalyzes the key steps of melanogenesis, making it a privileged target for reducing melanin production in vivo. However, very few hsTYR inhibitors have been reported so far in the literature, whereas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059e03d13aa685219f1c63c816ddfa20
https://pubmed.ncbi.nlm.nih.gov/36462443
https://pubmed.ncbi.nlm.nih.gov/36462443
Publikováno v:
Journal of Medicinal Chemistry. 63:13428-13443
Human tyrosinase (hsTYR) is the key enzyme ensuring the conversion of l-tyrosine to dopaquinone, thereby initiating melanin synthesis, i.e., melanogenesis. Although the protein has long been familiar, knowledge about its three-dimensional structure a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5adecfd6db6fa04e83e1c21abd7a9a
https://doi.org/10.1021/acs.jmedchem.0c00994
https://doi.org/10.1021/acs.jmedchem.0c00994
Autor:
Laura Goracci, Alessandra Nurisso, Emile Roussel, Basile Pérès, Vincent Chaptal, Pierre Falson, Christelle Marminon, Joachim Jose, Marc Le Borgne, Ahcène Boumendjel
Publikováno v:
European Journal of Medicinal Chemistry. 248:115070
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a5cf10972a4fcb0ef044e7df3506f6
https://doi.org/10.1016/j.ejmech.2022.115070
https://doi.org/10.1016/j.ejmech.2022.115070
Autor:
Aline Thomas, Emile Roussel, Pierre Falson, Alexis Moreno, Basile Pérès, Olivier Renaudet, Ahcène Boumendjel, Nicolas Altounian, Christian Philouze
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112503. ⟨10.1016/j.ejmech.2020.112503⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112503. ⟨10.1016/j.ejmech.2020.112503⟩
The Breast Cancer Resistance Protein (BCRP/ABCG2) belongs to the G class of ABC (ATP-Binding Cassette) proteins, which is known as one of the main transporters involved in the multidrug resistance (MDR) phenotype that confer resistance to anticancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c965dd9032deb4bd9f722d7efe3090f
https://hal.archives-ouvertes.fr/hal-03075331
https://hal.archives-ouvertes.fr/hal-03075331
Autor:
Doriane Lorendeau, Vincent Chaptal, Pierre Falson, Ruttiros Khonkarn, Hélène Baubichon-Cortay, Rachad Nasr, Jean-Claude Cortay, Ahcène Boumendjel, Lauriane Dury, Basile Pérès
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.7616. ⟨10.1038/s41598-020-64400-x⟩
Scientific Reports, 2020, 10 (1), pp.7616. ⟨10.1038/s41598-020-64400-x⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports, Nature Publishing Group, 2020, 10 (1), pp.7616. ⟨10.1038/s41598-020-64400-x⟩
Scientific Reports, 2020, 10 (1), pp.7616. ⟨10.1038/s41598-020-64400-x⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
The transporter Multidrug Resistance Protein 1 (MRP1, ABCC1) is implicated in multidrug resistant (MDR) phenotype of cancer cells. Glutathione (GSH) plays a key role in MRP1 transport activities. In addition, a ligand-stimulated GSH transport which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a122457c14a1d3f038b2209c93ad5ff3
https://www.hal.inserm.fr/inserm-02863457/file/s41598-020-64400-x.pdf
https://www.hal.inserm.fr/inserm-02863457/file/s41598-020-64400-x.pdf
Autor:
Shweta Nim, Pratima Baghel, Pierre Falson, Viet-Khoa Tran-Nguyen, Attilio Di Pietro, Ahcène Boumendjel, Rajendra Prasad, Kim-Anh Nguyen, Basile Pérès
Publikováno v:
Future Medicinal Chemistry
Future Medicinal Chemistry, Future Science, 2018, 10 (18), pp.2177-2186. ⟨10.4155/fmc-2018-0081⟩
Future Medicinal Chemistry, Future Science, 2018, 10 (18), pp.2177-2186. ⟨10.4155/fmc-2018-0081⟩
International audience; Aim: Resistance against antifungals used for Candida albicans (Ca) treatment is mediated by two multidrug transporters, Mdr1p and Cdr1p, which are of enormous interest to the development of modulators combined with antifungals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2093e087061a7daf4c9ee2ac5b7bc615
https://doi.org/10.4155/fmc-2018-0081
https://doi.org/10.4155/fmc-2018-0081
Autor:
Olivier Renaudet, Ahcène Boumendjel, Amine Belaidi, Pierre Falson, Viet-Khoa Tran-Nguyen, Emile Roussel, Ammar Azioune, Brahim Matougui, Mohamed Abdesselem Dems, Khalid Bouhedjar, Basile Pérès
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2019, 184, pp.111772. ⟨10.1016/j.ejmech.2019.111772⟩
European Journal of Medicinal Chemistry, Elsevier, 2019, 184, pp.111772. ⟨10.1016/j.ejmech.2019.111772⟩
The membrane transporter BCRP/ABCG2 has emerged as a privileged biological target for the development of small compounds capable of abolishing multidrug resistance. In this context, the chromone skeleton was found as an excellent scaffold for the des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6200eff2e668b732c99f998b690d9b67
https://hal.archives-ouvertes.fr/hal-02442448
https://hal.archives-ouvertes.fr/hal-02442448
Autor:
Basile Pérès, Marc Maresca, Hamza Olleik, Akram Hijazi, Josette Perrier, Samir Yahiaoui, Ahcène Boumendjel, Elias Baydoun, Brayan Roulier, Elise Courvoisier-Dezord, Romain Haudecoeur, Josette Raymond
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2019, 165, pp.133-141. ⟨10.1016/j.ejmech.2019.01.022⟩
European Journal of Medicinal Chemistry, 2019, 165, pp.133-141. ⟨10.1016/j.ejmech.2019.01.022⟩
European Journal of Medicinal Chemistry, Elsevier, 2019, 165, pp.133-141. ⟨10.1016/j.ejmech.2019.01.022⟩
European Journal of Medicinal Chemistry, 2019, 165, pp.133-141. ⟨10.1016/j.ejmech.2019.01.022⟩
International audience; A set of variously substituted aurones was synthesized and evaluated against Methicillin-Resistant S. aureus (MRSA) and P. aeruginosa. Several analogues were found active against MRSA, but no effect was recorded against P. aer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55b6940df138732c0235b38bfbdd3e5
https://pubmed.ncbi.nlm.nih.gov/30665143
https://pubmed.ncbi.nlm.nih.gov/30665143