Výsledky vyhledávání - "Basil O. Ibe"

Akademický článek

Mechanism by which nuclear factor-kappa beta (NF-kB) regulates ovine fetal pulmonary vascular smooth muscle cell proliferation

Autor: Uchenna D. Ogbozor, Michael Opene, Lissette S. Renteria, Shaemion McBride, Basil O. Ibe

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 4, Iss C, Pp 11-18 (2015)

Platelet activating factor (PAF) modulates ovine fetal pulmonary hemodynamic. PAF acts through its receptors (PAFR) in pulmonary vascular smooth muscle cells (PVSMC) to phosphorylate and induce nuclear translocation of NF-kB p65 leading to PVSMC prol

Externí odkaz: https://doaj.org/article/52604e4eca4342e38805d9d5c40dc5fc

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Platelet Activating Factor Receptor Binding and Contractile Protein Expression by Ovine Fetal Pulmonary Vascular Smooth Muscle Cells: Role in Rho Kinase Mediation of PAF Receptor-Linked Physiological Responses

Autor: Lissette S. Renteria, Basil O. Ibe, Stephen M Douglass, Amy M. Douglass

Publikováno v: Medical Research Archives. 9

We studied effects of hypoxia and some modulators of PAFR–mediated signaling in fetal ovine arterial and venous smooth muscle cells to aid in explaining PAF regulation of fetal pulmonary hemodynamics in utero. PAFR, a G protein coupled receptor, is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3f24e855708fa0f4dca4a56d50d3263
https://doi.org/10.18103/mra.v9i7.2460

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Physiological and Biochemical Consequences of Exposure of Neonatal Rats to Chronic Hypoxia

Autor: May F. Abdallah, Basil O. Ibe, J. U. Raj

Publikováno v: Medical Research Archives. 8

We studied effect of chronic hypoxia (CH) on expression of platelet activating factor receptor (PAFR) by neonatal rats (pups). We hypothesized that PAFR antagonist will prevent pulmonary hypertension (PH) in pups exposed to CH. Pups were placed in an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::628ae7719e4a59e966831057043feaa9
https://doi.org/10.18103/mra.v8i10.2249

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Thalamic mediation of hypoxic respiratory depression in lambs

Autor: Brian J. Koos, Lawrence Kruger, Basil O. Ibe, Arezoo Rajaee, Catalina Guerra

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 310:R586-R595

Immaturity of respiratory controllers in preterm infants dispose to recurrent apnea and oxygen deprivation. Accompanying reductions in brain oxygen tensions evoke respiratory depression, potentially exacerbating hypoxemia. Central respiratory depress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d2ee791f8172868f83b3e9aeead7ab
https://doi.org/10.1152/ajpregu.00412.2015

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Rho Kinase inhibitors and hypoxia modulate expression of platelet activating factor (PAF) receptor and gene expression in fetal ovine pulmonary vascular smooth muscle cells

Autor: Basil O. Ibe, Lissette S. Renteria

Publikováno v: The FASEB Journal. 32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d937bd085d4f6370a71da40669b8fd97
https://doi.org/10.1096/fasebj.2018.32.1_supplement.700.4

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Mechanism by which nuclear factor-kappa beta (NF-kB) regulates ovine fetal pulmonary vascular smooth muscle cell proliferation

Autor: Michael Opene, Basil O. Ibe, Uchenna D. Ogbozor, Lissette S. Renteria, Shaemion McBride

Publikováno v: Molecular Genetics and Metabolism Reports, Vol 4, Iss C, Pp 11-18 (2015)
Molecular Genetics and Metabolism Reports

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864a1327d0a077aec8bed80d5344c856
http://www.sciencedirect.com/science/article/pii/S2214426915300112

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Sickle Erythrocytes and Platelets Augment Lung Leukotriene Synthesis with Downregulation of Anti‐Inflammatory Proteins: Relevance in the Pathology of the Acute Chest Syndrome

Autor: Joseph Kurantsin-Mills, Michael Opene, Sumair Husain, Basil O. Ibe

Publikováno v: Pulmonary Circulation. 4:482-495

Initiation, progression, and resolution of vaso-occlusive pain episodes in sickle cell disease (SCD) have been recognized as reperfusion injury, which provokes an inflammatory response in the pulmonary circulation. Some 5-lipoxygenase (5-lox) metabol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78505911bb6ea949841bbcb3414ab42f
https://doi.org/10.1086/677363

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Hypoxia and hyperoxia potentiate PAF receptor-mediated effects in newborn ovine pulmonary arterial smooth muscle cells: significance in oxygen therapy of PPHN

Autor: Basil O. Ibe, Shaemion McBride, Gilberto Bernal, Mona Hanouni, Vincent Reginald F. Narvaez

Publikováno v: Physiological Reports

Platelet‐activating factor (PAF) acting via its receptor (PAFR) is implicated in the pathogenesis of persistent pulmonary hypertension of the newborn (PPHN). Effects of long‐term oxygen therapy on newborn lung are not well understood; therefore,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48f5d0177d80f5f477c62d92dad2b8e
https://pubmed.ncbi.nlm.nih.gov/27354543

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Albuterol Isomers Modulate Platelet-Activating Factor Synthesis and Receptor Signaling in Human Bronchial Smooth Muscle Cells

Autor: Basil O. Ibe, Alba Arteaga, J. Usha Raj, Rena Bae

Publikováno v: International Archives of Allergy and Immunology. 158:18-26

Background: Racemic albuterol is a 50:50 mixture of the (R)- and (S)-enantiomers of albuterol. Its clinical efficacy resides in the (R)-enantiomer (levalbuterol). Studies have shown that (S)-albuterol induces human bronchial smooth muscle cell (HBSMC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae81d0775df3d29180c619c7a5c5748
https://doi.org/10.1159/000330029

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