Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Basil J Petrof"'
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194421 (2018)
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness which is ultimately fatal, most often due to involvement of the diaphragm. Macrophage infiltration of dystrophic muscles has been strongly linked to muscle damage and f
Externí odkaz:
https://doaj.org/article/0605e973c83440a7a0b6bc5961c41a22
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177723 (2017)
The ability to accurately determine respiratory muscle strength is vitally important in patients with neuromuscular disorders (NMD). Sniff nasal inspiratory pressure (SNIP), a test of inspiratory muscle strength, is easier to perform for many NMD pat
Externí odkaz:
https://doaj.org/article/7774f95169ac4cf09a6f9f923b42fb03
Autor:
Kamalika Mojumdar, Feng Liang, Christian Giordano, Christian Lemaire, Gawiyou Danialou, Tatsuma Okazaki, Johanne Bourdon, Moutih Rafei, Jacques Galipeau, Maziar Divangahi, Basil J Petrof
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 11, Pp 1476-1492 (2014)
Abstract Myofiber necrosis and fibrosis are hallmarks of Duchenne muscular dystrophy (DMD), leading to lethal weakness of the diaphragm. Macrophages (MPs) are required for successful muscle regeneration, but the role of inflammatory monocyte (MO)‐d
Externí odkaz:
https://doaj.org/article/5bd888cbe11c473faafe74115f7758bf
Autor:
Douglas A McKim, Jeremy Road, Monica Avendano, Steve Abdool, Fabien Côté, Nigel Duguid, Janet Fraser, François Maltais, Debra L Morrison, Colleen O’Connell, Basil J Petrof, Karen Rimmer, Robert Skomro, Canadian Thoracic Society Home Mechanical Ventilation Committee
Publikováno v:
Canadian Respiratory Journal, Vol 18, Iss 4, Pp 197-215 (2011)
Increasing numbers of patients are surviving episodes of prolonged mechanical ventilation or benefitting from the recent availability of user-friendly noninvasive ventilators. Although many publications pertaining to specific aspects of home mechanic
Externí odkaz:
https://doaj.org/article/60dcef673aca4844babb443293b5e0ca
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131068 (2015)
Short-term intermittent hypoxia (IH) is common in patients with acute respiratory disorders. Although prolonged exposure to hypoxia induces atrophy and increased fatigability of skeletal muscle, the response to short-term IH is less well known. We hy
Externí odkaz:
https://doaj.org/article/00611331e1ce4d3ea659871169e10463
Autor:
Maziar Divangahi, Haouaria Balghi, Gawiyou Danialou, Alain S Comtois, Alexandre Demoule, Sheila Ernest, Christina Haston, Renaud Robert, John W Hanrahan, Danuta Radzioch, Basil J Petrof
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000586 (2009)
Cystic fibrosis (CF) patients often have reduced mass and strength of skeletal muscles, including the diaphragm, the primary muscle of respiration. Here we show that lack of the CF transmembrane conductance regulator (CFTR) plays an intrinsic role in
Externí odkaz:
https://doaj.org/article/922b93df895c415bad69e05d3490893f
Autor:
Vanessa Moarbes, Dominique Mayaki, Laurent Huck, Philippe Leblanc, Theodoros Vassilakopoulos, Basil J. Petrof, Sabah N. A. Hussain
Publikováno v:
Physiological Reports, Vol 7, Iss 20, Pp n/a-n/a (2019)
Abstract Sepsis elicits skeletal muscle atrophy as a result of decreased total protein synthesis and/or increased total protein degradation. It is unknown how and whether sepsis differentially affects the expression of specific myofibrillar proteins
Externí odkaz:
https://doaj.org/article/c1a6190db40244c5a5fd5408c913dbe5
Autor:
Maryam Oskoui, Marta Kaminska, Evelyn Constantin, David Zielinski, Jean N. Westenberg, Francine Noel, Basil J. Petrof
Publikováno v:
J Clin Sleep Med
STUDY OBJECTIVES: Sleep-disordered breathing (SDB) is common in patients with neuromuscular disorders (NMD), developing before chronic hypercapnia appears. Polysomnography (PSG) is the diagnostic gold standard but is often impractical and poorly acce
Autor:
Debra L. Morrison, Karen P. Rimmer, Marta Kaminska, François Maltais, Douglas A McKim, Colleen O'Connell, Mika Nonoyama, Eleni Giannouli, Basil J. Petrof
Publikováno v:
Canadian Journal of Respiratory, Critical Care, and Sleep Medicine. 5:160-183
BACKGROUND: Chronic hypercapnic respiratory failure is common in advanced chronic obstructive pulmonary disease (COPD) and it is associated with adverse outcomes such as repeat hospitalization and ...
Autor:
Ekaterina Gusev, Feng Liang, Salyan Bhattarai, Felipe E. Broering, Jean-Philippe Leduc-Gaudet, Sabah N. Hussain, Danuta Radzioch, Basil J. Petrof
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 322(6)
Patients with cystic fibrosis (CF) often suffer from skeletal muscle atrophy, most often attributed to physical inactivity and nutritional factors. CF is also characterized by abnormally elevated systemic inflammation. However, it is unknown whether