Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Basil I Swanson"'
Autor:
Shailja Jakhar, Ramamurthy Sakamuri, Dung Vu, Priya Dighe, Loreen R Stromberg, Laura Lilley, Nicolas Hengartner, Basil I Swanson, Emmanuel Moreau, Susan E Dorman, Harshini Mukundan
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0243337 (2021)
Lipoarabinomannan (LAM), an amphiphilic lipoglycan of the Mycobacterium tuberculosis cell wall, is a diagnostic target for tuberculosis. Previous work from our laboratory and others suggests that LAM is associated with host serum lipoproteins, which
Externí odkaz:
https://doaj.org/article/d62daf74bd3d4722b928ad81319755d5
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 2, p e1005972 (2018)
Mycolactone is the exotoxin produced by Mycobacterium ulcerans and is the virulence factor behind the neglected tropical disease Buruli ulcer. The toxin has a broad spectrum of biological effects within the host organism, stemming from its interactio
Externí odkaz:
https://doaj.org/article/9343a1d15f8e4a7a897ba8afa8e2e86f
Autor:
M Lisa Phipps, Antoinetta M Lillo, Yulin Shou, Emily N Schmidt, Chad D Paavola, Leslie Naranjo, Sara Bemdich, Basil I Swanson, Andrew R M Bradbury, Jennifer S Martinez
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0160940 (2016)
Peptides are important affinity ligands for microscopy, biosensing, and targeted delivery. However, because they can have low affinity for their targets, their selection from large naïve libraries can be challenging. When selecting peptidic ligands
Externí odkaz:
https://doaj.org/article/a14a429d1cf94888b031aa2aef531c09
Publikováno v:
Methods in Molecular Biology ISBN: 9781071617786
Methods Mol Biol
Methods Mol Biol
The successful isolation of mycolactone in a laboratory or from a clinical sample relies on proper handling and storage of the toxin. Mycolactone is a light-sensitive and an amphiphilic toxin produced by Mycobacterium ulcerans. The biochemistry of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0ff7a2addf7cd0e769f060fa8e6672
https://doi.org/10.1007/978-1-0716-1779-3_12
https://doi.org/10.1007/978-1-0716-1779-3_12
Autor:
Emmanuel Moreau, Laura M. Lilley, Basil I. Swanson, Susan E. Dorman, Shailja Jakhar, Dung M. Vu, Priya Dighe, Loreen R. Stromberg, Nicolas W. Hengartner, Harshini Mukundan, Ramamurthy Sakamuri
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0243337 (2021)
PLoS ONE
PLoS ONE
Lipoarabinomannan (LAM), an amphiphilic lipoglycan of the Mycobacterium tuberculosis cell wall, is a diagnostic target for tuberculosis. Previous work from our laboratory and others suggests that LAM is associated with host serum lipoproteins, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544464b197a7100a112796681fe1b733
https://doi.org/10.1101/2020.11.20.391037
https://doi.org/10.1101/2020.11.20.391037
Autor:
Paul J. Converse, Eric L. Nuermberger, Jessica Z. Kubicek-Sutherland, Ricardo Marti-Arbona, Basil I. Swanson, Harshini Mukundan, Dung M. Vu, Aaron S. Anderson, Timothy C. Sanchez
Publikováno v:
Toxins
Volume 11
Issue 4
Toxins, Vol 11, Iss 4, p 202 (2019)
Volume 11
Issue 4
Toxins, Vol 11, Iss 4, p 202 (2019)
Mycolactone, the amphiphilic macrolide toxin secreted by Mycobacterium ulcerans, plays a significant role in the pathology and manifestations of Buruli ulcer (BU). Consequently, it follows that the toxin is a suitable target for the development of di
Publikováno v:
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 33(4)
Early and rapid detection of bovine tuberculosis (bTB) is critical to controlling the spread of this disease in cattle and other animals. In this study, we demonstrate the development of an immunoassay for the direct detection of the bovine bTB bioma
Autor:
Laura E. Via, Sang Nae Cho, Harshini Mukundan, Clifton E. Barry, Dominique N. Price, Basil I. Swanson, Myungsun Lee, Rama Murthy Sakamuri
Publikováno v:
Tuberculosis. 93:301-307
Understanding the pathophysiology of tuberculosis, and the bio-distribution of pathogen-associated molecules in the host is essential for the development of efficient methods of intervention. One of the key virulence factors in the pathology of tuber
Publikováno v:
Biophysical Journal. 104:622-632
Sugar recognition at the membrane is critical in various physiological processes. Many aspects of sugar-membrane interaction are still unknown. We take an integrated approach by combining conventional molecular-dynamics simulations with enhanced samp
Autor:
Chad D. Paavola, Emily N. Schmidt, Basil I. Swanson, Yulin Shou, Sara Bemdich, Leslie Naranjo, Antoinetta M. Lillo, Jennifer S. Martinez, M. Lisa Phipps, Andrew Bradbury
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0160940 (2016)
PLoS ONE
PLoS ONE
Peptides are important affinity ligands for microscopy, biosensing, and targeted delivery. However, because they can have low affinity for their targets, their selection from large naïve libraries can be challenging. When selecting peptidic ligands