Výsledky vyhledávání - "Basic calcium phosphate crystals"

Akademický článek

Publikováno v: Reumatismo, Vol 63, Iss 4, Pp 221-229 (2012)

Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physico

Externí odkaz: https://doaj.org/article/c5e58560858f4b0d9f62cdf3102d7e70

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Effect of pathogenic crystals on the production of pro- and anti-inflammatory cytokines by different leukocyte populations

Autor: Andrea Doria, Jean-Michel Dayer, Roberta Ramonda, Leonardo Punzi, Francesca Oliviero, Roberto Luisetto, Anna Scanu

Purpose To evaluate cytokine production in vitro by different types of leukocytes stimulated with monosodium urate (MSU), calcium pyrophosphate (CPP) and basic calcium phosphate (BCP) crystals. Material and methods Polymorphonuclear cells (PMN), mono

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5496b7a065641e15ded1191ee55c61
http://hdl.handle.net/11577/3361145

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Akademický článek

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Basic calcium phosphate and pyrophosphate crystals in early and late osteoarthritis: relationship with clinical indices and inflammation

Autor: Paola Galozzi, Leonardo Punzi, Francesca Oliviero, Anna Scanu, Roberta Ramonda, Luca Peruzzo, Leonardo Tauro, Paola Frallonardo

Publikováno v: Clinical rheumatology (Print.) 37 (2018): 2847–2853. doi:10.1007/s10067-018-4166-3
info:cnr-pdr/source/autori:Frallonardo P.; Ramonda R.; Peruzzo L.; Scanu A.; Galozzi P.; Tauro L.; Punzi L.; Oliviero F./titolo:Basic calcium phosphate and pyrophosphate crystals in early and late osteoarthritis: relationship with clinical indices and inflammation/doi:10.1007%2Fs10067-018-4166-3/rivista:Clinical rheumatology (Print.)/anno:2018/pagina_da:2847/pagina_a:2853/intervallo_pagine:2847–2853/volume:37

The current study aimed to investigate the association of calcium pyrophosphate (CPP) and basic calcium phosphate (BCP) crystals in synovial fluid (SF) of patients with osteoarthritis (OA) with disease severity, clinical symptoms, and synovial inflam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77026f7986174dbda0bba019e7751b85
https://publications.cnr.it/doc/391848

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Molecular mechanisms of pain in crystal-induced arthritis

Autor: Roberta Ramonda, Leonardo Punzi, Mariagrazia Lorenzin, Paola Frallonardo, Francesca Oliviero, Paola Galozzi, Anna Scanu, Augusta Ortolan

Publikováno v: Best Practice & Research Clinical Rheumatology. 29:98-110

Crystal-induced arthritis (CIA) is characterized by an intense inflammatory reaction triggered by the deposition of monosodium urate, calcium pyrophosphate, and basic calcium phosphate crystals in articular and periarticular tissues. Severe, acute pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c00ea7ba0431921a46571bc91b8f7c2
https://doi.org/10.1016/j.berh.2015.04.025

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Microsomal prostaglandin E2 synthase 1 expression in basic calcium phosphate crystal-stimulated fibroblasts: role of prostaglandin E2 and the EP4 receptor

Autor: Geraldine M. McCarthy, Maria P. Morgan, J. O'Byrne, Desmond J. Fitzgerald, Glen A. Doherty, Brendan P. McDonnell, Eamonn S. Molloy

Publikováno v: Osteoarthritis and Cartilage. 17(5):686-692

Summary Objective Basic calcium phosphate (BCP) crystals have been implicated in the pathogenesis of osteoarthritis (OA), in part because of their ability to upregulate cyclooxygenase and prostaglandin E 2 (PGE 2 ) production. The aim of this work wa

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BCP crystals increase prostacyclin production and upregulate the prostacyclin receptor in OA synovial fibroblasts: potential effects on mPGES1 and MMP-13

Autor: Eamonn S. Molloy, Maria P. Morgan, J. O'Byrne, Geraldine M. McCarthy, Brendan P. McDonnell

Publikováno v: Osteoarthritis and Cartilage. 15(4):414-420

Summary Objective To investigate the potential involvement of prostacyclin in basic calcium phosphate (BCP) crystal-induced responses in osteoarthritic synovial fibroblasts (OASF). Methods OASF grown in culture were stimulated with BCP crystals. Pros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c289b7ae3548d0bb873d567aaeda3db8

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Intracellular calcium responses to basic calcium phosphate crystals in fibroblasts

Autor: Paul B. Halverson, Andrew S. Greene, Herman S. Cheung

Publikováno v: Osteoarthritis and Cartilage. 6:324-329

Objective: To examine the intracellular calcium response to basic calcium phosphate (BCP) crystals in fibroblasts. Design: In this study, intracellular calcium [Ca 2+ ] i levels in fibroblasts were determined using the photoactive dye, fura-2. Interr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1292957e47c61b4f5d8db3a28e8357aa
https://doi.org/10.1053/joca.1998.0131

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