Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Basic Science Research Papers"'
Autor:
Peter Crauwels, Susi Krämer, Stefan Tenzer, Rebecca Bohn, Elena Bank, Max Bastian, Ger van Zandbergen, Stefan Gottwalt, Paul Walther, Florian Jäckel, Meike Thomas
Publikováno v:
Autophagy
Apoptosis is a well-defined cellular process in which a cell dies, characterized by cell shrinkage and DNA fragmentation. In parasites like Leishmania, the process of apoptosis-like cell death has been described. Moreover upon infection, the apoptoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d4c51b6d0167edde6a36126fbd4617
http://europepmc.org/articles/PMC4502818
http://europepmc.org/articles/PMC4502818
Autor:
Laura Pellegrini, Matteo Antonio Russo, Marco Tafani, Lucia Polletta, Massimo Fini, Emanuela Morgante, Enza Vernucci, Silvia Palmerio, Ilaria Carnevale, Alessandra Runci, Lidia Villanova, Luigi Sansone, Tania Arcangeli, Dante Rotili, Antonello Mai, Theresa Nowak, Clemens Steegborn, Bruna Pucci, Mike Schutkowski
Publikováno v:
Autophagy
In liver the mitochondrial sirtuin, SIRT5, controls ammonia detoxification by regulating CPS1, the first enzyme of the urea cycle. However, while SIRT5 is ubiquitously expressed, urea cycle and CPS1 are only present in the liver and, to a minor exten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291eeba0ec2dffac9aba51bbc536950e
https://doi.org/10.1080/15548627.2015.1009778
https://doi.org/10.1080/15548627.2015.1009778
Autor:
Yusuke Kurihara, Tomotake Kanki, Xiulian Jin, Shun-ichi Yamashita, Tetsu Saigusa, Dongchon Kang, Masamune Aihara, Yuko Hirota
Publikováno v:
Autophagy. 11:332-343
In cultured cells, not many mitochondria are degraded by mitophagy induced by physiological cellular stress. We observed mitophagy in HeLa cells using a method that relies on the pH-sensitive fluorescent protein Keima. With this approach, we found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa7145e45e2c23caf941cf14eb6e950
https://doi.org/10.1080/15548627.2015.1023047
https://doi.org/10.1080/15548627.2015.1023047
Autor:
Yan Yu, Min Xie, Liangchun Yang, Lizhi Cao, Liying Liu, Shan Zhu, Xiaofang Sun, Daolin Tang, Rui Kang, Minghua Yang
Publikováno v:
Autophagy. 11:214-224
Both apoptosis ("self-killing") and autophagy ("self-eating") are evolutionarily conserved processes, and their crosstalk influences anticancer drug sensitivity and cell death. However, the underlying mechanism remains unclear. Here, we demonstrated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a5a194bf638050d4f940ed6264e250
https://doi.org/10.4161/15548627.2014.994400
https://doi.org/10.4161/15548627.2014.994400
Autor:
Marion Gröger, Barbara Lengauer, Manfred Fobker, Heidemarie Rossiter, Christine Hartmann, Caterina Barresi, Johannes Pammer, Ulrich Koenig, Guenter P. Resch, Marlene Brandstetter, Gabriele Plenz
Publikováno v:
Autophagy
The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid droplets, while type B cells produce dark granules of multilamellar bodies. The process of autoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5f1be40fdbf952623720bdaf3372c8
https://doi.org/10.4161/15548627.2014.978221
https://doi.org/10.4161/15548627.2014.978221
Autor:
Lekha Dinesh Kumar, Debaraj Mukherjee, Reyaz ur Rasool, Debasis Nayak, Bilal Rah, Syed Khalid Yousuf, Anindya Goswami
An active medicinal component of plant origin with an ability to overcome autophagy by inducing apoptosis should be considered a therapeutically active lead pharmacophore to control malignancies. In this report, we studied the effect of concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416999eb0af63bb3794828b45ad13cc3
https://europepmc.org/articles/PMC4502794/
https://europepmc.org/articles/PMC4502794/
Autor:
Gadi Lalazar, Kathryn E. Tanaka, Mark J. Czaja, Muhammad Haseeb, Kun Liu, Yu Lin, Ghulam Ilyas, Enpeng Zhao
Recent evidence that excessive lipid accumulation can decrease cellular levels of autophagy and that autophagy regulates immune responsiveness suggested that impaired macrophage autophagy may promote the increased innate immune activation that underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9509f77d543dd18b1ad3a6fa3cf494c
https://europepmc.org/articles/PMC4502775/
https://europepmc.org/articles/PMC4502775/
Autor:
Caiyun Zhou, Xinyu Wang, Weiguo Lu, Jian-Yang Zhang, Songfa Zhang, Xing Xie, Feng Ye, Zhiqin Fu, Xiaodong Cheng, Qiaohua Peng, Yunfeng Fu
Paclitaxel is recommended as a first-line chemotherapeutic agent against ovarian cancer, but drug resistance becomes a major limitation of its success clinically. The key molecule or mechanism associated with paclitaxel resistance in ovarian cancer s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefde001780c5b4f6e81bcb76a79c372
https://europepmc.org/articles/PMC4502659/
https://europepmc.org/articles/PMC4502659/
Autor:
Dan Dan Li, Rong Deng, Jing Hong Chen, Lin Jiao, Jian Wei Jiang, Wen Dan Chen, Xiao Feng Zhu, Jiao Ji, Xiao Qi Wu, Peng Zhang, Xuan Li, Yi Xin Zeng, Gong Kan Feng
PTEN (phosphatase and tensin homolog), a tumor suppressor frequently mutated in human cancer, has various cytoplasmic and nuclear functions. PTEN translocates to the nucleus from the cytoplasm in response to oxidative stress. However, the mechanism a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e4831105895cfc0e51e96342d06c7b
Autor:
Jiang Gu, Marissa Wang, Yong-jun Jiao, Qian Li, Yin-ping Jia, Quanming Zou, Pan Zhu, Li Jingxin, Hai-guang Wang, Na Li, Bin Tang, Xuhu Mao, Yao Fang, Kun Wang, Xiu-hua Zhao, Feng-cai Zhu, Wende Tong
Shiga toxins (Stxs) are a family of cytotoxic proteins that lead to the development of bloody diarrhea, hemolytic-uremic syndrome, and central nervous system complications caused by bacteria such as S. dysenteriae, E. coli O157:H7 and E. coli O104:H4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bec65a7beafb26f01e9cc0d6864b044