Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Basic Science Aspects"'
Autor:
Seilitz, Jenny, Grafver, Isabelle, Kiszakiewicz, Lars, Oikonomakis, Ioannis, Jansson, Kjell, Axelsson, Birger, Nilsson, Kristofer F.
Publikováno v:
Shock (Augusta, Ga.)
Background: Splanchnic vasodilation by inodilators is an argument for their use in critical cardiac dysfunction. To isolate peripheral vasoactivity from inotropy, such drugs were investigated, and contrasted to vasopressors, in a fixed low cardiac ou
Autor:
Yan Yang, Shuiqing Hu, Ling Tu, Ying Tang, Ruolan Dong, Zhihui Chen, Xizhen Xu, Jinlan Luo, Dao Wen Wang, Menglu Fu, Jing Yu
Publikováno v:
Shock (Augusta, Ga.)
Background: Sepsis is a life-threatening organ dysfunction initiated by a dysregulated response to infection, with imbalanced inflammation and immune homeostasis. Macrophages play a pivotal role in sepsis. N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(t
Publikováno v:
Shock (Augusta, Ga.)
Regulatory guidelines mandate housing for laboratory mice at temperatures below their thermoneutral zone, creating chronic cold stress. However, increases in housing temperature could alter immune responses. We hypothesized housing mice at temperatur
Autor:
Takayuki Irahara, Kazuo Inoue, Kosuke Otake, Satoru Murata, Norio Sato, Hiroyuki Yokota, Kaoru Koike
Publikováno v:
Shock (Augusta, Ga.)
This study investigated the therapeutic benefits of neuromuscular electrical stimulation (NMES). C57BL/6 mice were administered lipopolysaccharide (LPS; 20 mg/kg body weight) by intraperitoneal injection and divided into control (C) and NMES groups (
Autor:
Shupeng Lin, Quan Hong, Li Tang, Xiangmei Chen, Guangyan Cai, Xue-yuan Bai, Jing Cui, Xuefeng Sun
Publikováno v:
Shock (Augusta, Ga.)
The clinical use of gentamicin over prolonged periods is limited because of dose and time-dependent nephrotoxicity, in which intracellular oxidative stress and heightened inflammation have been implicated. Macroautophagy/autophagy is an essential and
Autor:
Masaru Suzuki, Ryo Yamamoto, Mayumi Kajimura, Koichiro Homma, Yoshinori Katsumata, Tomoyoshi Tamura, Junichi Sasaki, Tadashi Matsuoka, Jin Endo, Motoaki Sano, Eiji Kobayashi, Joe Yoshizawa
Publikováno v:
Shock (Augusta, Ga.)
Supplemental Digital Content is available in the text
Background: Hydrogen gas (H2) inhalation during hemorrhage stabilizes post-resuscitation hemodynamics, improving short-term survival in a rat hemorrhagic shock and resuscitation (HS/R) model.
Background: Hydrogen gas (H2) inhalation during hemorrhage stabilizes post-resuscitation hemodynamics, improving short-term survival in a rat hemorrhagic shock and resuscitation (HS/R) model.
Publikováno v:
Shock (Augusta, Ga.)
FTY720 is a sphingosine 1 phosphate (S1P) receptor agonist approved for the treatment of multiple sclerosis, which is a chronic inflammatory autoimmune disorder. Sepsis is a complex syndrome associated with progressive endotoxemic developments, which
Autor:
Tal M. Hörer, Linus Beskow, Fredrik Calais, Birger Axelsson, Kristofer F. Nilsson, Emanuel M. Dogan
Publikováno v:
Shock (Augusta, Ga.)
Introduction: Aortic occlusion during cardiopulmonary resuscitation (CPR) increases systemic arterial pressures. Correct thoracic placement during the resuscitative endovascular balloon occlusion of the aorta (REBOA) may be important for achieving ef
Autor:
Quan Li, Jing-Yan Han, Xiao-Hong Wei, Xin Chang, Chun-Shui Pan, Jing-Yu Fan, Bai-He Hu, Yu-Ying Liu, Jian-Yuan Luo, Hong-Na Mu, Li Yan, Dan-Dan Huang
Publikováno v:
Shock (Augusta, Ga.)
Supplemental Digital Content is available in the text
Sirtuin1 (Sirt1) and Sirtuin3 (Sirt3) are known to participate in regulating mitochondrial function. However, whether Total Salvianolic Acid Injection (TSI) protects against myocardial ischem
Sirtuin1 (Sirt1) and Sirtuin3 (Sirt3) are known to participate in regulating mitochondrial function. However, whether Total Salvianolic Acid Injection (TSI) protects against myocardial ischem
Autor:
Peter J. Zwiers, Nicolette C. A. Huijkman, Matijs van Meurs, Bart van de Sluis, Jill Moser, Jan G. Zijlstra, Daphne Dekker, Henk E. Moorlag, Rianne M. Jongman, Eliane R. Popa, Grietje Molema, Marleen van der Laan
Publikováno v:
Shock (Augusta, Ga.)
Shock, 51(6), 757-769. LIPPINCOTT WILLIAMS & WILKINS
Shock, 51(6), 757-769. LIPPINCOTT WILLIAMS & WILKINS
Supplemental Digital Content is available in the text
Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences o
Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences o