Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Basic/Translational Research"'
Autor:
Mitchell B. Sally, Darren J. Malinoski, Frank P. Zaldivar, Tony Le, Matin Khoshnevis, William A. Pinette, Michael Hutchens, Shlomit Radom-Aizik
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 208-216 (2018)
IntroductionA majority of transplanted organs come from donors after brain death (BD). Renal grafts from these donors have higher delayed graft function and lower long-term survival rates compared to living donors. We designed a novel porcine BD mode
Externí odkaz:
https://doaj.org/article/95de83179e394273b908791c4a3e2ccd
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 5, Pp 600-609 (2021)
Investigative and Clinical Urology
Investigative and Clinical Urology
Purpose Ischemia disrupts cellular energy homeostasis. Adenosine monophosphate-activated protein kinase alpha-2 (AMPK-α2) is a subunit of AMPK that senses cellular energy deprivation and signals metabolic stress. Our goal was to examine the expressi
Autor:
Anita Limanjaya, Min Ji Choi, Jiyeon Ock, Mi-Hye Kwon, Ji Kan Ryu, Jun Kyu Suh, Kalyan Ghatak, Guo Nan Yin, Kang-Moon Song
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 1, Pp 90-99 (2021)
Investigative and Clinical Urology
Investigative and Clinical Urology
Purpose To investigate potential target genes associated with the diabetic condition in mouse cavernous endothelial cells (MCECs) for the treatment of diabetes-induced erectile dysfunction (ED). Materials and Methods Mouse cavernous tissue was embedd
Autor:
Zhen Li Gao, Guo Nan Yin, Lei Shi, Hai Rong Jin, Jun-Kyu Suh, Ji-Kan Ryu, Jitao Wu, Yuanshan Cui, Chunhua Lin
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 1, Pp 100-110 (2021)
Investigative and Clinical Urology
Investigative and Clinical Urology
Purpose Penile erection requires integrative interactions between vascular endothelial cells, pericytes, smooth muscle cells, and autonomic nerves. Furthermore, the importance of the role played by pericytes in the pathogenesis of angiopathy has only
Publikováno v:
Investigative and Clinical Urology
Investigative and Clinical Urology, Vol 62, Iss 6, Pp 690-696 (2021)
Investigative and Clinical Urology, Vol 62, Iss 6, Pp 690-696 (2021)
Purpose This study aimed to develop a simple nomogram based on the Mayo Adhesive Probability (MAP) score combined with the RENAL nephrometry score (RNS) to predict intraoperative complications before partial nephrectomy (PN) in Asian populations. Mat
Autor:
Sang Hun Lee, Song Hee Kim, Abdumadjidov Alisher Abdulkhayevich, Won Hyeok Lee, Seong Cheol Kim, Young Min Kim, Jeong Woo Park, Kyung Hyun Moon, Sungchan Park
Publikováno v:
Investigative and Clinical Urology
Investigative and Clinical Urology, Vol 62, Iss 4, Pp 485-495 (2021)
Investigative and Clinical Urology, Vol 62, Iss 4, Pp 485-495 (2021)
Purpose This study aimed to confirm the association between developmentally regulated GTP-binding protein 2 (DRG2) expression and docetaxel-induced apoptosis and to determine whether prostate cancer responses to docetaxel treatment differ with DRG2 e
Publikováno v:
Investigative and Clinical Urology
Purpose To explore the effect of estrogen replacement on pelvic floor and bladder contractile response to electrical field stimulation, following in vitro hypoxia in an animal model of surgical menopause. Materials and Methods Twelve female adult rab
Autor:
Seong Soo Jeon, Joung Eun Lim, Hwang Gyun Jeon, Junnam Lee, Hyun Moo Lee, Minyong Kang, Joongwon Choi, Hyun Hwan Sung, Byong Chang Jeong, Seong Il Seo, Jiwoong Yu, Eun-Hae Cho
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 2, Pp 224-232 (2021)
Investigative and Clinical Urology
Investigative and Clinical Urology
Purpose To investigate germline and somatic mutation profiles in Korean patients with prostate cancer using liquid biopsy and solid tissue testing and to evaluate the prognostic value of circulating tumor DNA (ctDNA) in predicting castration resistan
Autor:
Joon Chae Na, Jee-Hoon Kim, Sook Young Kim, Young-Ran Gu, Dae-Young Jun, Hyung Ho Lee, Young Eun Yoon, Kyung Hwa Choi, Sung Joon Hong, Woong Kyu Han
Publikováno v:
Investigative and Clinical Urology, Vol 61, Iss 2, Pp 216-223 (2020)
Investigative and Clinical Urology
Investigative and Clinical Urology
Purpose: Renal cell carcinoma is a heterogeneous kidney cancer, and over 403,000 cases were reported worldwide in 2018. Current methods for studying renal cell carcinoma are limited to two-dimensional (2D) culture of primary cell lines and patient-de
Autor:
Dae Keun Kim, Su-Jin Shin, Jiyoung Lee, Sung Yul Park, Yong Tae Kim, Hong Yong Choi, Young Eun Yoon, Hong Sang Moon
Publikováno v:
Investigative and Clinical Urology
Investigative and Clinical Urology, Vol 61, Iss 4, Pp 441-451 (2020)
Investigative and Clinical Urology, Vol 61, Iss 4, Pp 441-451 (2020)
Purpose: Despite the role of carbon monoxide in ameliorating ischemia-reperfusion injury (IRI), its use in the clinical setting is restricted owing to its toxicity. Herein, we investigated the in vivo effects of carbon monoxide–releasing molecule-3