Výsledky vyhledávání - "Basem Qeshta"

Akademický článek

Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents

Autor: Saeb Aliwaini, Bassam Abu Thaher, Ihab Al-Masri, Nabil Shurrab, Said El-Kurdi, Dieter Schollmeyer, Basem Qeshta, Mariam Ghunaim, René Csuk, Stefan Laufer, Lars Kaiser, Hans-Peter Deigner

Publikováno v: Molecules, Vol 26, Iss 13, p 4065 (2021)

Three novel pyrazolo-[4,3-e][1,2,4]triazolopyrimidine derivatives (1, 2, and 3) were designed, synthesized, and evaluated for their in vitro biological activity. All three compounds exhibited different levels of cytotoxicity against cervical and brea

Externí odkaz: https://doaj.org/article/a77c83942f3d4f95a43c4dc95beddc7d

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Akademický článek

Crystal structures of pure 3-(4-bromo-2-chlorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one and contaminated with 3-(4-bromophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one

Autor: Kanan Wahedy, Bassam Abu Thaher, Dieter Schollmeyer, Ihab Almasri, Rami Morjan, Basem Qeshta, Hans-Peter Deigner

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications, Vol 73, Iss 9, Pp 1341-1343 (2017)

The side product of the cyclocondensation reaction between ethyl benzimidazole-2-carboxylate and the nitrile imine of the corresponding hydrazonyl chloride, C20H11BrClN5O, crystallized in two crystal forms. Form (1) is a co-crystal of the target comp

Externí odkaz: https://doaj.org/article/0f1f129ff07240c689b3eae17f4fc5a9

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Akademický článek

1-(Pyridin-4-yl)-3-(2,4,6-trichlorophenyl)benz[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one

Autor: Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Kanan M. Wahedy, Ihab M. Almasri, Rami Y. Morjan, Hans-Peter Deigner

Publikováno v: IUCrData, Vol 1, Iss 10, p x161529 (2016)

In the title compound, C20H10Cl3N5O, the 13-membered ring system makes dihedral angles of 78.64 (9)° with the trichlorophenyl ring and 62.60 (10)° with the pyridine ring. The crystal packing is dominated by π–π interactions between the 13-membe

Externí odkaz: https://doaj.org/article/20696b3abbe84317a41da44c5ee94f7c

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Akademický článek

3-(2,4-Difluorophenyl)-1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]triazin-4(3H)-one

Autor: Bassam Abu Thaher, Dieter Schollmeyer, Basem Qeshta, Hans-Peter Deigner

Publikováno v: IUCrData, Vol 1, Iss 9, p x161380 (2016)

In the title compound, C20H11F2N5O, the central 13-membered ring system (r.m.s. deviation = 0.028 Å) makes a dihedral angle of 53.13 (7)° with the difluorophenyl ring and 79.98 (7)° with the pyridine ring. The crystal packing features aromatic π�

Externí odkaz: https://doaj.org/article/cb645e2f402e48e7a7da285888d1277c

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Synthesis and bioassay of 3-Aryl -1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]- triazin-4(3H)-ones as anti-cancer agents

Autor: Bassam Abu Thaher, Ihab Al-Masri, Kanan Wahedy, Rami Morjan, Saeb Aliwaini, Iman Mahmoud Al atter, Aayat Ahmed Elmabhouh, Areej khaled AL ibwaini, Saba Luay Alkhaldi, Basem Qeshta, Claus Jacob, Hans-Peter Deigner

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology.

Four novel 3-Aryl -1-(pyridin-4-yl)benzo[4,5]imidazo[1,2-d][1,2,4]- triazin-4(3H)-ones derivatives (C1 to C4) have been designed, synthesized, and evaluated for their anticancer activity. The structure of compounds was characterized by IR,1H NMR, 13C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d686ded0bbf2bc5ba9bd9a26f7b11c
https://doi.org/10.1007/s00210-023-02433-5

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Autor: Kanan Wahedy, Bassam Abu Thaher, Dieter Schollmeyer, Ihab Almasri, Rami Morjan, Basem Qeshta, Hans-Peter Deigner

Publikováno v: Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications, Vol 73, Iss 9, Pp 1341-1343 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba4f82d7d529f0efd06701ba7ab7735
http://europepmc.org/articles/PMC5588576

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