JBP1 and JBP3 have conserved structures but different affinity to base-J.

Autor: de Vries I; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Adamopoulos A; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Kazokaitė-Adomaitienė J; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Heidebrecht T; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Fish A; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Celie PHN; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Joosten RP; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands., Perrakis A; Oncode Institute and Division of Biochemistry at the Netherlands Cancer Institute - Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address: a.perrakis@nki.nl.

Publikováno v: Journal of structural biology [J Struct Biol] 2024 Dec 12; Vol. 217 (1), pp. 108161. Date of Electronic Publication: 2024 Dec 12.

Behind Base J: The Roles of JBP1 and JBP2 on Trypanosomatids

Autor: Luiz Henrique de Castro Assis, Stephany Cacete de Paiva, Maria Isabel Nogueira Cano

Publikováno v: Pathogens, Vol 12, Iss 3, p 467 (2023)

β-D-glucopyranosyloxymethiluracil (Base J) is a modified thymidine base found in kinetoplastids and some related organisms. Interestingly, Base J distribution into the genome can vary depending on the organism and its life stage. Base J is reported

Externí odkaz: https://doaj.org/article/69ff94b2fd8a40ddb4249bbbcf908d54

The domain architecture of the protozoan protein J-DNA–binding protein 1 suggests synergy between base J DNA binding and thymidine hydroxylase activity

Autor: Adamopoulos, Athanassios, Heidebrecht, Tatjana, Roosendaal, Jeroen, Touw, Wouter G., Phan, Isabelle Q., Beijnen, Jos, Perrakis, Anastassis

Publikováno v: In Journal of Biological Chemistry 23 August 2019 294(34):12815-12825

Facile Enzymatic Synthesis of Base J-Containing Oligodeoxyribonucleotides and an Analysis of the Impact of Base J on DNA Replication in Cells.

Autor: Ji, Debin¹, Wang, Yinsheng¹ yinsheng.wang@ucr.edu

Publikováno v: PLoS ONE. Jul2014, Vol. 9 Issue 7, p1-7. 7p.

Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei.

Autor: Schulz, Danae¹, Zaringhalam, Maryam¹, Papavasiliou, F. Nina¹ papavasiliou@rockefeller.edu, Kim, Hee-Sook¹ khee-sook@rockefeller.edu

Publikováno v: PLoS Genetics. 1/21/2016, Vol. 12 Issue 1, p1-21. 21p.