Výsledky vyhledávání - "Basavdutta R. Ghosh"

Transcriptional Activation of the Ovine Follicle-Stimulating Hormone β-Subunit Gene by Gonadotropin-Releasing Hormone: Involvement of Two Activating Protein-1-Binding Sites and Protein Kinase C**This work was supported by the North Carolina State University Agricultural Research Service, NICHD Grant 34863, and the Mellon Foundation

Autor: Basavdutta R. Ghosh, Joseph Sebastian, Huey Jing Huang, William L. Miller, Brian D. Strahl

Publikováno v: Endocrinology. 139:4455-4465

FSH is an α/β heterodimeric glycoprotein, the formation of which is regulated primarily by expression of its β-subunit. Recent studies on transcriptional regulation of the ovine FSH β-subunit gene (oFSHβ) have defined two functional activating p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a719c41fe96e9d3317233187bca0236d
https://doi.org/10.1210/endo.139.11.6281

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Isolation of Nine Different Biologically and Immunologically Active Molecular Variants of Bovine Follicular Inhibin1

Autor: James J. Ireland, Basavdutta R. Ghosh, J. Pulaski, J.L.H. Ireland, Patty S.D. Weber, Tara E.M. Good, Vasantha Padmanabhan, Alan L. Schneyer, N. Groome, G. Lambert-Messerlian, William L. Miller

Publikováno v: Biology of Reproduction. 53:1478-1488

A combination of immunoaffinity chromatography, SDS-PAGE, and electroelution was used to simultaneously isolate 0.36-4.65 mg of nine different molecular forms of inhibin (proac-29 kDa; fully processed 34 kDa; and large inhibin forms 49, 53, 58, 77, 8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4cc5c97faf5356d2f95623a86a5219b6
https://doi.org/10.1095/biolreprod53.6.1478

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Two proximal activating protein-1-binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone-beta gene

Autor: Basavdutta R. Ghosh, Huey Jing Huang, Norma R. Pedersen, Brian D. Strahl, William L. Miller, Joyce C. Wu

Publikováno v: Endocrinology. 138(6)

FSH is an important regulator of mammalian gametogenesis and the female reproductive cycle. Although little is known about the transcriptional regulation of the beta-subunit (the rate-limiting subunit of FSH synthesis), sequence analysis of the ovine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b379e25e4b2c46aa3d4be1de6cddebac
https://pubmed.ncbi.nlm.nih.gov/9165057

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Inhibin and estradiol alter gonadotropes differentially in ovine pituitary cultures: changing gonadotrope numbers and calcium responses to gonadotropin-releasing hormone

Autor: Gwen V. Childs, Joyce C. Wu, William L. Miller, Brian D. Strahl, Basavdutta R. Ghosh

Publikováno v: Endocrinology. 137(11)

Both inhibin (IN) and estradiol (E) use separate and distinct mechanisms to decrease the production of FSH 60%-80% while increasing receptors for GnRH (GnRH-Rec) 400%-600% in ovine pituitary cultures. To investigate how these hormones act to create o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8647bfd0e98174728c48e57f3e9275d
https://pubmed.ncbi.nlm.nih.gov/8895389

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Gonadotropin-releasing hormone-stimulated calcium mobilization is altered in pituitary cultures from anestrous ewes

Autor: Basavdutta R. Ghosh, William L. Miller, Joyce C. Wu

Publikováno v: Biology of reproduction. 54(4)

GnRH transiently increases intracellular calcium ([Ca 2+ ] i ) in pituitary gonadotrophs in culture. This effect is observed within 10 sec of GnRH treatment, lasts 1-5 min, and is thought to be an important intracellular signal leading to the secreti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1778b8ddeb4bb9504b6e278e2f994e03
https://pubmed.ncbi.nlm.nih.gov/8924493

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