Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Basavarajaiah Swethakumar"'
Autor:
Gajanan D. Katkar, Mahalingam S. Sundaram, Somanathapura K. NaveenKumar, Basavarajaiah Swethakumar, Rachana D. Sharma, Manoj Paul, Gopalapura J. Vishalakshi, Sannaningaiah Devaraja, Kesturu S. Girish, Kempaiah Kemparaju
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The saw-scaled viper venom causes continued tissue damage that may cause death. Here the authors show that the venom attracts neutrophils to the bite site and induces neutrophil extracellular traps that capture venom components causing tissue damage,
Externí odkaz:
https://doaj.org/article/e5a4eac896c04b2da861157c352e0645
Autor:
Basavarajaiah Swethakumar, Somanathapura K. NaveenKumar, Kesturu S. Girish, Kempaiah Kemparaju
Publikováno v:
Biochimica et biophysica acta. General subjects. 1864(6)
Background Neutrophils are the first line defense cells of the innate immunity. As a final defense, they discharge their de-condensed chromatin/DNA fibers, the NETs (Neutrophil Extracellular Traps), by a process called NETosis. Two types of NETosis h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d6715c380b4ca6de5035d95c6f159b
https://pubmed.ncbi.nlm.nih.gov/32068016
https://pubmed.ncbi.nlm.nih.gov/32068016
Autor:
Somanathapura K. NaveenKumar, Rachana D. Sharma, Mahadevappa Hemshekhar, Gajanan D. Katkar, Mahalingam S. Sundaram, Manoj S. Paul, Kempaiah Kemparaju, Kesturu S. Girish, Basavarajaiah Swethakumar
Publikováno v:
Journal of Pineal Research. 59:240-254
Oxidative stress-induced methemoglobinemia remained an untouched area in venom pharmacology till date. This study for the first time explored the potential of animal venoms to oxidize hemoglobin to methemoglobin. In in vitro whole-blood assay, methem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec8ad0bab0cc415b831641644e365a6
https://doi.org/10.1111/jpi.12256
https://doi.org/10.1111/jpi.12256
Autor:
Rachana D. Sharma, Gajanan D. Katkar, Basavarajaiah Swethakumar, Kesturu S. Girish, Kempaiah Kemparaju, Mahalingam S. Sundaram
Publikováno v:
Acta tropica. 169
Snakebite is a neglected health hazard. Its patho-physiology has largely been focused on systemic and local toxicities; whereas, venom and antivenom induced oxidative stress has long been ignored. Antivenom therapy although neutralizes venom lethalit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9e8cdc0eaa6004a1e3a12814ed7aab
https://pubmed.ncbi.nlm.nih.gov/28089603
https://pubmed.ncbi.nlm.nih.gov/28089603
Autor:
Rachana D. Sharma, Gajanan D. Katkar, Mahalingam S. Sundaram, Gopalapura J. Vishalakshi, S. Devaraja, Somanathapura K. NaveenKumar, Kesturu S. Girish, Basavarajaiah Swethakumar, Manoj S. Paul, Kempaiah Kemparaju
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Indian Echis carinatus bite causes sustained tissue destruction at the bite site. Neutrophils, the major leukocytes in the early defence process, accumulate at the bite site. Here we show that E. carinatus venom induces neutrophil extracellular trap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6610673eedf8c883d9b692cb5c2b9c04
https://doi.org/10.1038/ncomms11361
https://doi.org/10.1038/ncomms11361