Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression

Autor: Victor Cervera-Carrascon, Victor W. van Beusechem, Ioanna Milenova, Dafne Carolina Alves Quixabeira, Tania Martiáñez, Basav Hangalapura, Connie R. Jimenez, Rik J. Scheper, Tanja D. de Gruijl, Henk L. Dekker, Sinéad M. Lougheed, Henk M.W. Verheul, Jos Joore, Marta López González, Jelle J. Lindenberg, Sander R. Piersma, Joao Manuel Santos, D. Oosterhoff, Akseli Hemminki, Rieneke van de Ven

Publikováno v: OncoImmunology
Oncoimmunology, 8, e1631119
OncoImmunology, Vol 8, Iss 10 (2019)
Oncoimmunology, 8, 10, pp. e1631119
Oncoimmunology
Gonzalez, M L, Oosterhoff, D, Lindenberg, J J, Milenova, I, Lougheed, S M, Martianez, T, Dekker, H, Quixabeira, D C A, Hangalapura, B, Joore, J, Piersma, S R, Cervera-Carrascon, V, Santos, J M, Scheper, R J, Verheul, H M W, Jimenez, C R, Van De Ven, R, Hemminki, A, Van Beusechem, V W & De Gruijl, T D 2019, ' Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression ', OncoImmunology, vol. 8, no. 10 . https://doi.org/10.1080/2162402X.2019.1631119
OncoImmunology, 8(10). Landes Bioscience

Contains fulltext : 215594.pdf (Publisher’s version ) (Open Access) In patients with cancer, the functionality of Dendritic Cells (DC) is hampered by high levels of tumor-derived suppressive cytokines, which interfere with DC development and matura

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