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pro vyhledávání: '"Basant Ebaid"'
Autor:
Basant Ebaid
A thesis submitted in total fulfilment of the requirements for the degree of Doctor of Philosophy to The Olivia Newton-John Cancer Research Institute, School of Cancer Medicine, College of Science, Health and Engineering, La Trobe University, Victori
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b0ad82400a739a4b65d5426197a833
Publikováno v:
Cancer Research. 79:823-823
Introduction: Over 90% of breast cancers occur sporadically with no obvious hereditary factors at play, therefore highlighting the need for biomarkers that can identify women who are predisposed to developing breast cancer. DNA methylation of the BRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893fe54efedbab12b5341f5d3c3bd906
https://doi.org/10.1158/1538-7445.am2019-823
https://doi.org/10.1158/1538-7445.am2019-823
Publikováno v:
Epigenetics & Chromatin
Background Phenotypic variability among inbred littermates reared in controlled environments remains poorly understood. Metastable epialleles refer to loci that intrinsically behave in this way and a few examples have been described. They display dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6258a211439f0d59a21987ce0a7e9fb1
https://pubmed.ncbi.nlm.nih.gov/26692901
https://pubmed.ncbi.nlm.nih.gov/26692901
Additional file 3: Fig. S2. Transposon insertions that differ between littermates. The genomes of two agouti viable yellow mice, one with yellow and one with pseudoagouti coat colour, were sequenced and searched for retrotransposon insertions, relati
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c1c185c4b7e4499000973d14f3fb28
Additional file 2: Fig. S1. (a) Read-coverage at a locus where a large gain of ~ 200 Kb of DNA is polymorphic in the Avy colony. Protein-coding genes are illustrated below the graph. (b) A total of six yellow (Y) and six pseudoagouti (P) mice,
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25560945551e45f7b16e5c27334925c1
Additional file 4: Fig. S3. Candidate differentially methylated regions between littermates. The mm9 genome were searched for sites that had a methylation values significantly different between the Pseudoagouti, C57.1, C57.2 and C57.3 mice with at le
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849b865ff71600a7d78576906a4cdb2e
Additional file 6: Fig. S5. Validation of DNA methylation at random non-ERV iiDMRs. WGBS weighted averages for DNA methylation values are shown for the nine loci chosen for pyrosequencing (a-i). The average pyrosequencing methylation level, from at l
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ef9ead89a2bc0fcaaac8f1c69cec6f
Additional file 5: Fig. S4. The range of methylation at ERV iiDMRs that overlap with IAP elements that have an internal sequence (n = 17) or are lone IAP LTR elements (n = 10). IAPs with internal sequence elements have a significantly greater range (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207f786798128bc80e27a4ab9651abd7