M1 cholinergic signaling in the brain modulates cytokine levels and splenic cell sub-phenotypes following cecal ligation and puncture

Autor: Mabel N. Abraham, Ana Nedeljkovic-Kurepa, Tiago D. Fernandes, Omar Yaipen, Mariana R. Brewer, Daniel E. Leisman, Matthew D. Taylor, Clifford S. Deutschman

Publikováno v: Molecular Medicine, Vol 30, Iss 1, Pp 1-11 (2024)

Abstract Background The contribution of the central nervous system to sepsis pathobiology is incompletely understood. In previous studies, administration of endotoxin to mice decreased activity of the vagus anti-inflammatory reflex. Treatment with th

Externí odkaz: https://doaj.org/article/1f6c39bde017455f943b50c9d73ef8c5

Increased functional connectivity between nucleus basalis of Meynert and amygdala in cognitively intact elderly along the Alzheimer’s continuum

Autor: Qingze Zeng, Tiantian Qiu, Kaicheng Li, Xiao Luo, Shuyue Wang, Xiaopei Xu, Xiaocao Liu, Luwei Hong, Jixuan Li, Peiyu Huang, Minming Zhang

Publikováno v: NeuroImage: Clinical, Vol 36, Iss , Pp 103256- (2022)

Background: A growing body of research reported the degeneration of the basal forebrain (BF) cholinergic system in the early course of Alzheimer’s disease (AD). However, functional changes of the BF in asymptomatic individuals along the Alzheimer�

Externí odkaz: https://doaj.org/article/d0b3bd6134f34169b7d459db26145d90

A single mild juvenile TBI in male mice leads to regional brain tissue abnormalities at 12 months of age that correlate with cognitive impairment at the middle age

Autor: Obenaus, Andre, Rodriguez-Grande, Beatriz, Lee, Jeong Bin, Dubois, Christophe J, Fournier, Marie-Line, Cador, Martine, Caille, Stéphanie, Badaut, Jerome

Publikováno v: Acta neuropathologica communications, vol 11, iss 1

Traumatic brain injury (TBI) has the highest incidence amongst the pediatric population and its mild severity represents the most frequent cases. Moderate and severe injuries as well as repetitive mild TBI result in lasting morbidity. However, whethe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::17dcd0b3ac6a2811efeaaec78190666f
https://escholarship.org/uc/item/7q9180c5

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Electroacupuncture in rats normalizes the diabetes-induced alterations in the septo-hippocampal cholinergic system

Autor: Lionel N.J.L. Marlier, Marzia Soligo, Stefano Farioli-Vecchioli, Maria Egle De Stefano, Virginia Protto, Robert Nisticò, Luigi Manni

Publikováno v: Hippocampus (Online) (2019). doi:10.1002/hipo.23088
info:cnr-pdr/source/autori:Protto V, Soligo M, De Stefano ME, Farioli-Vecchioli S, Marlier LNJL, Nisticò R, Manni L./titolo:Electroacupuncture in rats normalizes the diabetes-induced alterations in the septo-hippocampal cholinergic system/doi:10.1002%2Fhipo.23088/rivista:Hippocampus (Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume

Diabetes induces early sufferance in the cholinergic septo-hippocampal system, characterized by deficits in learning and memory, reduced hippocampal plasticity and abnormal pro-nerve growth factor (proNGF) release from hippocampal cells, all linked t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1e62f2a479fb9be0ef0ce26757fcf3
http://hdl.handle.net/2108/213257