Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bas Nagelkerken"'
Autor:
Danita H. Schuurhuis, Jolien J. van der Ploeg-van Schip, Bas Nagelkerken, Cornelis J. M. Melief, Andreea Ioan-Facsinay, J. Sjef Verbeek, Christine Sedlik, Ferry Ossendorp
Publikováno v:
The Journal of Immunology. 168:2240-2246
Dendritic cells (DCs) require a maturation signal to acquire efficient CTL-priming capacity. In vitro FcγR-mediated internalization of Ag-Ab immune complexes (ICs) can induce maturation of DCs. In this study, we show that IC-induced DC maturation in
Autor:
Alexander E.E Mertens, Inge H. Briaire-de Bruijn, Manon J. Winter, Sergey V. Litvinov, Hellen A.M Rees-Bakker, Bas Nagelkerken
Publikováno v:
Experimental cell research. 285(1)
Various adhesion molecules play an important role in defining cell fate and maintaining tissue integrity. Therefore, cross-signaling between adhesion receptors should be a common phenomenon to support the orchestrated changes of cells' connections to
Autor:
Jessica Holthuizen, Lisya Gerez, Nathalie O. P. van Uden, Lucas Pelkmans, Karin Mohrmann, Marcel van Raak, Peter van der Sluijs, Bas Nagelkerken, Eelco van Anken
Publikováno v:
Biochemical journal, 346 Pt 3, 593-601. Portland Press Ltd.
The small GTPase rab4a is associated with early endocytic compartments and regulates receptor recycling from early endosomes. To understand how rab4a mediates its function, we searched for proteins which associate with this GTPase and regulate its ac
Autor:
R. Leijendekker, Peter van der Sluijs, Lisya Gerez, Bas Nagelkerken, Marcel van Raak, Karin Mohrmann
Publikováno v:
Electrophoresis. 18(14)
Rab GTPases are localized on the cytoplasmic surface of most intracellular organelles where they play a role in the regulation of vesicular transport. As it has been difficult to detect endogenous rab proteins by morphological methods, their localiza
Autor:
Julian R. Sampson, Ans M.W. van den Ouweland, Arnold J. J. Reuser, Marjon van Slegtenhorst, Russell G. Snell, Mark Nellist, Bas Nagelkerken, Peter van der Sluijs, Dicky J. J. Halley, Jeremy Peter Cheadle
Publikováno v:
Human Molecular Genetics, 7(6), 1053-1057. Oxford University Press
Tuberous sclerosis (TSC) is an autosomal dominant disorder caused by a mutation in either the TSC1 or TSC2 tumour suppressor gene. The disease is characterized by a broad phenotypic spectrum that can include seizures, mental retardation, renal dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0c7e8e0892e04baff45b48e7c17d7c
https://pure.eur.nl/en/publications/b0a0e833-0092-4e2b-9c04-4c5216ad5c63
https://pure.eur.nl/en/publications/b0a0e833-0092-4e2b-9c04-4c5216ad5c63
Publikováno v:
Cytometry. 29(1)
Early endosomes are very dynamic intracellular membrane organelles that undergo multiple fusion and fission events. In this study, we developed a novel assay based on multiparametric flow cytometric analyses and early endosome sorting to characterize
Publikováno v:
The Journal of biological chemistry. 271(46)
Several Rab GTPases have been localized to distinct compartments of the endocytic pathway. Rab4 is associated with early endosomes and recycling vesicles and regulates membrane recycling from early endosomes. Rab7 is localized to late endosomes and i
Publikováno v:
Biochimica et biophysica acta. 1219(3)
The KlQCR8 gene of the yeast Kluyveromyces lactics encoding subunit VIII of the mitochondrial bc 1 complex is 70.2% identical to its counterpart in Saccharomyces cerevisiae (ScQCR8) . As in S. cerevisiae , chromosomal linkage between the K. lactis QC