Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Bas Jan M Van Der Leede"'
Autor:
William C. Gunther, Ann Schuermans, John Nicolette, Fabrice Nesslany, Ronald D. Fiedler, Stephen D. Dertinger, Céline Defrain, Laura Custer, Thomas J. Shutsky, Catherine J. Thiffeault, Robert H. Heflich, Paul Sonders, Amanda Giddings, Ljubica Krsmanovic, Javed A. Bhalli, Eleanor C. Wilde, Anthony M. Lynch, James T. MacGregor, Kevin Sweder, Osamu Tajima, Takafumi Kimoto, Andrew Henwood, Jing Shi, Terry Van Doninck, Souk Phonethepswath, Carol Gleason, Bas-jan M. van der Leede, Hans-Werner Vohr, Daniel J. Roberts, Pamela Weller, Azeddine Elhajouji, Yoshie Hiwata, Leon F. Stankowski, Joel Murray, Julia Kenny, Kentaro Tanaka
Publikováno v:
Environmental and Molecular Mutagenesis. 52:690-698
A collaborative international trial was conducted to evaluate the reproducibility and transferability of an in vivo mutation assay based on the enumeration of CD59-negative rat erythrocytes, a phenotype that is indicative of Pig-a gene mutation. Four
Autor:
E. Sonneveld, Christina E. van den Brink, Malcolm Maden, Paul T. van der Saag, Bas-jan M. van der Leede
Publikováno v:
Experimental Cell Research. 250:284-297
Embryonal carcinoma cell lines (F9 EC and P19 EC) were stably transfected with 1.8 kb promoter sequence of RARbeta2 coupled to the lacZ gene as a system for measuring active retinoids. These stable transfectants, designated F9-1.8 and P19-1.8, were u
Publikováno v:
Journal of Biological Chemistry. 272:16637-16643
Progesterone is an important regulator of normal and malignant breast epithelial cells. In addition to stimulating development of normal mammary epithelium, it can be used to treat hormone-dependent breast tumors. However, the mechanism of growth inh
Autor:
Stefan Westin, Agneta Mode, Paul T. van der Saag, Edwin Sonneveld, Bas Jan M Van Der Leede, Jan-Åke Gustafsson
Publikováno v:
Molecular and Cellular Endocrinology. 129:169-179
Rats deficient in vitamin A express low levels of P4502C7 mRNA in the liver. Administration of all-trans retinoic acid (at-RA) or growth hormone (GH) to deficient animals only partially restored the expression whereas the combined treatment returned
Autor:
Rivka Slager-Davidov, Bart van der Burg, Bas-jan M. van der Leede, Siegfried W. de Laat, Paul T. van der Saag
Publikováno v:
Molecular and Cellular Endocrinology. 112:143-152
We have studied the role of the AP1 transcription factor in the progression of human breast carcinomas. This progression is characterized by a loss of dependence for proliferation on mitogenic hormones, and is also linked to loss of responsiveness to
Autor:
Dorothea K, Torous, Nikki E, Hall, Anne H, Illi-Love, Marilyn S, Diehl, Karin, Cederbrant, Kerstin, Sandelin, Ingrid, Pontén, George, Bolcsfoldi, Lynnette R, Ferguson, Amira, Pearson, Jenness B, Majeska, James P, Tarca, Geoffrey M, Hynes, Anthony M, Lynch, James P, McNamee, Pascale V, Bellier, Monique, Parenteau, David, Blakey, Janet, Bayley, Bas-Jan M, van der Leede, Philippe, Vanparys, Philip R, Harbach, Shuou, Zhao, Anthony L, Filipunas, Carol W, Johnson, Carol R, Tometsko, Stephen D, Dertinger
Publikováno v:
Environmental and molecular mutagenesis. 45(1)
An interlaboratory study was performed to validate an anti-CD71/flow cytometry-based technique for enumerating micronucleated reticulocytes (MN-RETs) in mouse peripheral blood. These experiments were designed to address International Workshop on Geno
Autor:
Christina E. van den Brink, Bart van der Burg, Bas-jan M. van der Leede, Gert E. Folkers, Paul T. van der Saag
Publikováno v:
Molecular and cellular endocrinology. 109(1)
Retinoic acid (RA) inhibits proliferation of estrogen receptor (ER)-positive human breast cancer cells, but not the growth of ER-negative cells. We have shown previously that ER-positive cells express higher levels of retinoic acid receptor (RAR) alp
Autor:
Bart van der Burg, Linda Kwakkenbos-Isbrücker, Simone Salverda, Bas-jan M. van der Leede, Siegfried W. de Laat, Paul T. van der Saag
Publikováno v:
Molecular and cellular endocrinology. 91(1-2)
Retinoic acid (RA) strongly inhibits proliferation of the estrogen (E2)-dependent human breast cancer cell lines MCF7, T47D, and ZR75-1, but not the E2-independent and E2 receptor (ER)-negative lines MDA-MB231, MDA-MB468, BT20 and Hs578T. The specifi
Publikováno v:
Molecular carcinogenesis. 8(2)
Retinoic acid (RA) has profound effects on cell proliferation and differentiation both in vitro and in vivo. Many human cell lines are known to be sensitive to the growth-inhibitory action of RA. We analyzed established human solid tumor-derived cell
Publikováno v:
Biochemical and biophysical research communications. 188(2)
Recently three isoforms of the mouse retinoic acid receptor (mRAR beta 1, mRAR beta 2, mRAR beta 3) have been described, generated from the same gene (Zelent et al., 1991). The isoforms differ in their 5'-untranslated (5'-UTR) and A region, but have