Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bas J. G. Baaten"'
Autor:
Jeffrey Koury, Jerel Adam Fields, Rohan Shah, Amanda J. Roberts, Bas J. G. Baaten, Ricky Maung, Marcus Kaul, Daniel Ojeda-Juárez, Indira S. Harahap-Carrillo, Benjamin B. Gelman
Publikováno v:
Brain Behav Immun
People living with HIV (PLWH) continue to develop HIV-associated neurocognitive disorders despite combination anti-retroviral therapy. Lipocalin-2 (LCN2) is an acute phase protein that has been implicated in neurodegeneration and is upregulated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c233f6b1a642d1b5f45ad26ac80cfde9
https://europepmc.org/articles/PMC8153086/
https://europepmc.org/articles/PMC8153086/
Publikováno v:
PLoS Pathogens, Vol 8, Iss 4, p e1002641 (2012)
The early inflammatory response to influenza virus infection contributes to severe lung disease and continues to pose a serious threat to human health. The mechanisms by which neutrophils gain entry to the respiratory tract and their role during path
Externí odkaz:
https://doaj.org/article/c3c29d0733b944fda40a540ab4bd8a8b
Autor:
Lisa Elmén, Dennie T. Frederick, Yibo Xian, Bas J. G. Baaten, Yan Li, Amir Orian, Hyungsoo Kim, Robert Schmaltz, Kevin M. Brown, Glenn Merlino, Roberto Tinoco, Eytan Ruppin, Ali Khateb, Ilanit Boyango, Avinash Das Sahu, Eva Guijarro Perez, Yongmei Feng, Randal J. Kaufman, Chi-Ping Day, Ze'ev Ronai, Tao Long, Lihi Tzur, Gil Bar-Sela, Emily Avitan-Hersh, Marcus Bosenberg, Shiri K. Ashkenazi, Mitchell P. Levesque, Shoshana Roizman, Linda M. Bradley, Raphy Zarecki, Yu Fujita, Scott N. Peterson, Colin R. Goding, Kerrie L. Marie, Reinhard Dummer, Rafael S. Segura Muñoz, Shibu Yooseph, Keith T. Flaherty, Tongwu Zhang, Amanda E. Ramer-Tait, Igor Segota, Miguel A. Tam
Publikováno v:
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Li, Y, Tinoco, R, Elmén, L, Segota, I, Xian, Y, Fujita, Y, Sahu, A, Zarecki, R, Marie, K L, Feng, Y, Khateb, A, Frederick, D T, Ashkenazi, S K, Kim, H, Pérez-Guijarro, E, Day, C-P, Segura Muñoz, R S, Schmaltz, R, Yooseph, S, Tam, M A, Zhang, T, Avitan-Hersh, E, Tzur, L, Roizman, S, Boyango, I, Bar-Sela, G, Orian, A, Kaufman, R J, Bosenberg, M, Goding, C R, Baaten, B, Levesque, M P, Dummer, R, Brown, K M, Merlino, G, Ruppin, E, Flaherty, K T, Ramer-Tait, A, Long, T, Peterson, S N, Bradley, L M & Ronai, Z A 2019, ' Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice ', Nature Communications, vol. 10, 1492, pp. 1-16 . https://doi.org/10.1038/s41467-019-09525-y
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Li, Y, Tinoco, R, Elmén, L, Segota, I, Xian, Y, Fujita, Y, Sahu, A, Zarecki, R, Marie, K L, Feng, Y, Khateb, A, Frederick, D T, Ashkenazi, S K, Kim, H, Pérez-Guijarro, E, Day, C-P, Segura Muñoz, R S, Schmaltz, R, Yooseph, S, Tam, M A, Zhang, T, Avitan-Hersh, E, Tzur, L, Roizman, S, Boyango, I, Bar-Sela, G, Orian, A, Kaufman, R J, Bosenberg, M, Goding, C R, Baaten, B, Levesque, M P, Dummer, R, Brown, K M, Merlino, G, Ruppin, E, Flaherty, K T, Ramer-Tait, A, Long, T, Peterson, S N, Bradley, L M & Ronai, Z A 2019, ' Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice ', Nature Communications, vol. 10, 1492, pp. 1-16 . https://doi.org/10.1038/s41467-019-09525-y
Nature Communications
Accumulating evidence points to an important role for the gut microbiome in anti-tumor immunity. Here, we show that altered intestinal microbiota contributes to anti-tumor immunity, limiting tumor expansion. Mice lacking the ubiquitin ligase RNF5 exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034278988dcad7bc3424498560983469
https://doi.org/10.1038/s41467-019-09525-y
https://doi.org/10.1038/s41467-019-09525-y
Autor:
Phillip M. Shelton, Fei Bao, Maria T. Diaz-Meco, Elias A. Castilla, Jorge Moscat, Jianfeng Huang, Yuki Nakanishi, Darren Sigal, Ferran Soldevila, Antoine L’Hermitte, Naoko Nakanishi, Munveer S. Bhangoo, Bas J. G. Baaten, Daniele V.F. Tauriello, Angeles Duran, Miguel Reina-Campos
Summary Serrated adenocarcinoma, an alternative pathway for colorectal cancer (CRC) development, accounts for 15%–30% of all CRCs and is aggressive and treatment resistant. We show that the expression of atypical protein kinase C ζ (PKCζ) and PKC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ce7d347af9b3c3c1e94c4f5d4b4ecb
https://europepmc.org/articles/PMC6301096/
https://europepmc.org/articles/PMC6301096/
Autor:
Fabiana I.A.L. Layng, Marco Maruggi, Petrus R. de Jong, Monica Sevilla, Brian P. James, Ferran Soldevilla, Bas J. G. Baaten, Mei Yee Koh, Robert Lemos, Garth Powis, Guillermina Garcia
Publikováno v:
Cancer Res
Cancer cells respond to hypoxia by upregulating the hypoxia-inducible factor 1α (HIF1A) transcription factor, which drives survival mechanisms that include metabolic adaptation and induction of angiogenesis by VEGF. Pancreatic tumors are poorly vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06686c77e18d1532d085ef87f6204926
https://pubmed.ncbi.nlm.nih.gov/31585939
https://pubmed.ncbi.nlm.nih.gov/31585939
Publikováno v:
Communicative & Integrative Biology. 3:508-512
CD44 is a widely-expressed adhesion receptor that is associated with diverse biological processes involving migrating cells, including inflammation, angiogenesis, bone metabolism and wound healing. In the immune system, CD44 is upregulated after acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aecb26b2a2225cb45748bb688b2e4d0
https://doi.org/10.4161/cib.3.6.13495
https://doi.org/10.4161/cib.3.6.13495
Autor:
Elana Godebu, Daphne Mahriah Summers-Torres, Bas J. G. Baaten, Melissa M. Lin, Linda M. Bradley
Publikováno v:
The Journal of Immunology. 181:1798-1805
Type 1 diabetes is a CD4 cell-dependent disease that results from destruction of insulin-producing β cells in pancreatic islets. An ideal therapy would reverse diabetes shortly after onset when islet function in not yet fully ablated, and also preve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fa547bff71cd2bf9c578ce4065574a6
https://doi.org/10.4049/jimmunol.181.3.1798
https://doi.org/10.4049/jimmunol.181.3.1798
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology, Vol 4 (2013)
T cell migration is crucial for an effective adaptive immune response to invading pathogens. Naive and memory T cells encounter pathogen antigens, become activated, and differentiate into effector cells in secondary lymphoid tissues, and then migrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc421078574f5268502023afd518410
https://pubmed.ncbi.nlm.nih.gov/24115949
https://pubmed.ncbi.nlm.nih.gov/24115949
Autor:
Stephen Soonthornvacharin, Linda M. Bradley, John L. Stebbins, Elisa Barile, Bas J. G. Baaten, Angel Bottini, Sumit K. Chanda, Maurizio Pellecchia, Surya K. De, Bainan Wu
Successful replication of the influenza A virus requires both viral proteins and host cellular factors. In this study we used a cellular assay to screen for small molecules capable of interfering with any of such necessary viral or cellular component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f735afb77bbb4dd82b81cf090c0215
https://europepmc.org/articles/PMC3769975/
https://europepmc.org/articles/PMC3769975/
Type 1 diabetes (T1D) results from autoimmune destruction of insulin-producing β-cells in the pancreatic islets. There is an immediate need to restore both β-cell function and immune tolerance to control disease progression and ultimately cure T1D.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3365dd13ad2c52998f3eacda33678e4
https://europepmc.org/articles/PMC3269299/
https://europepmc.org/articles/PMC3269299/