Zinc finger 1 of the RING E3 ligase, RNF125, interacts with the E2 to enhance ubiquitylation.

Autor: Middleton AJ; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand., Barzak FM; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand., Fokkens TJ; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand., Nguyen K; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand., Day CL; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9054, New Zealand. Electronic address: catherine.day@otago.ac.nz.

Publikováno v: Structure (London, England : 1993) [Structure] 2023 Oct 05; Vol. 31 (10), pp. 1208-1219.e5. Date of Electronic Publication: 2023 Aug 03.

Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity.

Autor: Barzak FM; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Ryan TM; SAXS/WAXS, Australian Synchrotron/ANSTO, 800 Blackburn Road, Clayton, VIC 3168, Australia., Mohammadzadeh N; Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Harjes S; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Kvach MV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Kurup HM; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand., Krause KL; Department of Biochemistry, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Chelico L; Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada., Filichev VV; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Harjes E; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand., Jameson GB; School of Natural Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand.; Maurice Wilkins Centre, University of Auckland, Auckland 1142, New Zealand.

Publikováno v: Viruses [Viruses] 2022 Sep 06; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 06.

Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.

Autor: Kvach MV; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Barzak FM; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Harjes S; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand., Schares HAM; Department of Medicinal Chemistry, University of Minnesota, 2231 6th Street SE, Minneapolis, MN, 55455, USA., Kurup HM; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Jones KF; Department of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN, 55455, USA., Sutton L; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN, 37232, USA., Donahue J; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, 21st Ave S, Nashville, TN, 37232, USA., D'Aquila RT; Division of Infectious Diseases and, Northwestern HIV Translational Research Center, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 N. St. Clair Street, Suite 2330, Chicago, IL, 60611, USA., Jameson GB; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Harki DA; Department of Medicinal Chemistry, University of Minnesota, 2231 6th Street SE, Minneapolis, MN, 55455, USA.; Department of Chemistry, University of Minnesota, 207 Pleasant St SE, Minneapolis, MN, 55455, USA., Krause KL; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand.; Department of Biochemistry, University of Otago, P. O. Box 56, Dunedin, 9054, New Zealand., Harjes E; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand., Filichev VV; School of Fundamental Sciences, Massey University, Private Bag 11 222, Palmerston North, 4442, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Private Bag 92019, Auckland, 1142, New Zealand.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2020 Apr 01; Vol. 21 (7), pp. 1028-1035. Date of Electronic Publication: 2019 Dec 19.

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.

Autor: Kvach MV; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand., Barzak FM; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand., Harjes S; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand., Schares HAM, Jameson GB; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery , Auckland 1142 , New Zealand., Ayoub AM, Moorthy R, Aihara H, Harris RS; Howard Hughes Medical Institute , University of Minnesota , Minneapolis , Minnesota 55455 , United States., Filichev VV; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery , Auckland 1142 , New Zealand., Harki DA, Harjes E; Institute of Fundamental Sciences , Massey University , Private Bag 11 222, Palmerston North 4442 , New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery , Auckland 1142 , New Zealand.

Publikováno v: Biochemistry [Biochemistry] 2019 Feb 05; Vol. 58 (5), pp. 391-400. Date of Electronic Publication: 2018 Nov 28.