Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes

Autor: Saeed, Ali, Bartuzi, Paulina, Heegsma, Janette, Dekker, Daphne, Kloosterhuis, Niels, de Bruin, Alain, Jonker, Johan W., van de Sluis, Bart, Faber, Klaas Nico

Publikováno v: In Cellular and Molecular Gastroenterology and Hepatology 2021 11(1):309-325

A cell-type-specific role for murine Commd1 in liver inflammation

Autor: Bartuzi, Paulina, Wijshake, Tobias, Dekker, Daphne C, Fedoseienko, Alina, Kloosterhuis, Niels J, Youssef, Sameh A, Li, Haiying, Shiri-Sverdlov, Ronit, Kuivenhoven, Jan-Albert, de Bruin, Alain, Burstein, Ezra, Hofker, Marten H, van de Sluis, Bart, LS Pathobiologie, Tissue Repair, PB TR

Publikováno v: Biochimica et Biophysica Acta, 1842(11), 2257
Biochimica et biophysica acta-Molecular basis of disease, 1842(11), 2257-2265. ELSEVIER SCIENCE BV
Biochimica et Biophysica Acta-Molecular Basis of Disease, 1842(11), 2257-2265. Elsevier Science

The transcription factor NF-kappa B plays a critical role in the inflammatory response and it has been implicated in various diseases, including non-alcoholic fatty liver disease (NAFLD). Although transient NF-kappa B activation may protect tissues f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd2e67475f61ab54b589037e78df498
https://doi.org/10.1016/j.bbadis.2014.06.035

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Autor: Bartuzi, Paulina, Billadeau, Daniel D, Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H, Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K, Elliott, Alison M, Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D, Burstein, Ezra, Hofker, Marten H, van de Sluis, Bart, Sub Hepatologie, LS Interne geneeskunde, dCSCA RMSC-1, dCSCA AVR

Publikováno v: Nature Communications, 7:10961. Nature Publishing Group
Nature Communications [E], 7. Nature Publishing Group
Nature communications, 7. Nature Publishing Group
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

The low-density lipoprotein receptor (LDLR) plays a pivotal role in clearing atherogenic circulating low-density lipoprotein (LDL) cholesterol. Here we show that the COMMD/CCDC22/CCDC93 (CCC) and the Wiskott–Aldrich syndrome protein and SCAR homolo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d0d772ce51e51aba88b348940c2e56
https://doi.org/10.1038/ncomms10961

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