Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Bartsch JW"'
Publikováno v:
73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCP151 /20220525/
Objective: Knowledge of individual time-to-recurrence (TTR) of GBM patients is critical to enable life-prolonging repeated surgery. MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules of 21 to 25 nucleotides and related to numerous tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ff9a5bba0f711f33b8fdf82d4453a0
Publikováno v:
73. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Griechischen Gesellschaft für Neurochirurgie; 20220529-20220601; Köln; DOCP154 /20220525/
Objective: About 95 % of GBM patients show tumor relapse leaving them with limited therapeutic options as recurrent tumors are often resistant to temozolomide (TMZ). GBM-like stem cells (GSCs) are considered as the major obstacle in therapy resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620f49cf4d24f4feb4c413554cece7fd
Publikováno v:
72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP053 /20210604/
Objective: Knowledge of individual time-to-recurrence (TTR) of GBM patients is critical to enable life-prolonging repeated surgery. MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules of 21 to 25 nucleotides and related to numerous tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db5e72b214ab068f29fb55dcf2098ee
Publikováno v:
72. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Polnischen Gesellschaft für Neurochirurgie; 20210606-20210609; sine loco [digital]; DOCP058 /20210604/
Objective: About 95 % ofGBM patients show tumor relapse leaving them with limited therapeutic options as recurrent tumors are often resistant to temozolomide (TMZ). GBM-like stem cells (GSCs) are considered as the major obstacle in therapy resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aaa8f36fc88a8c47a33484bbe34b2ec
Publikováno v:
71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCP117 /20200626/
Objective: Calcium-dependent proteases (calpains) are involved in GBM cell infiltration and in therapy resistance. Calpains are cysteine proteases, naturally inhibited by Calpastatins, are highly expressed in tumor cells, and could serve as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10846691bd6431777e625a575989cb2
Publikováno v:
70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie; 20190512-20190515; Würzburg; DOCP071 /20190508/
Objective: Infiltration of tumor cells into the surrounding brain tissue and development of resistance mechanisms towards adjuvant radio- and chemotherapy are two main aspects that need to be addressed in order to establish an effective treatment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bcdc62ac1282b8a437d4697c8796b4
Publikováno v:
69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie; 20180603-20180606; Münster; DOCP078 /20180618/
Objective: For most types of pituitary adenomas, such as primary prolactinomas or pituitary adenomas that produce growth hormone, a successful drug-based therapeutic approach has been established. In contrast, non-hormone secreting adenomas must be r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e355b00733218aaff8d8a45efb9700bb
Publikováno v:
69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie; 20180603-20180606; Münster; DOCP087 /20180618/
Objective: Intercellular communication, driven by tumor-associated microglia/macrophages and metalloproteases engaged in limited proteolysis are important factors contributing to the grim prognosis of GBM patients. We investigated the occurrence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aadd5d1c29dc051bfbd7c8cbbe3cd6f
Publikováno v:
67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCP 027 /20160608/
Objective: A hallmark of gliomas is their diffuse infiltration in surrounding CNS tissue. Zinc is an essential element for the observed glioma migration and invasion. Zinc utilisation is controlled by zinc transporters and through buffering by metall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7f1128daeaddbdc9b063156c24cb9b
Publikováno v:
67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCP 028 /20160608/
Objective: In the tumor microenvironment, ADAMs as zinc-dependent metalloproteases are important mediators of tumor cell growth, cell migration and tumor angiogenesis. ADAM8 as a metalloprotease is highly expressed in ~54% of high-grade gliomas and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f509dbff5270d6cdc3448e9e7d3b3e10