Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

ω-Functionalized Lipid Prodrugs of HIV NtRTI Tenofovir with Enhanced Pharmacokinetic Properties

Autor: Pribut, Nicole, D’Erasmo, Michael, Dasari, Madhuri, Giesler, Kyle E., Iskandar, Sabrina, Sharma, Savita K., Bartsch, Perry W., Raghuram, Akshay, Bushnev, Anatoliy, Hwang, Soyon S., Burton, Samantha L., Derdeyn, Cynthia A., Basson, Adriaan E., Liotta, Dennis C., Miller, Eric J.

Publikováno v: Journal of Medicinal Chemistry; September 2021, Vol. 64 Issue: 17 p12917-12937, 21p

Discovery of 5'-Substituted 5-Fluoro-2'-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors.

Autor: Dasari M; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Pelly SC; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Geng J; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Gold HB; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Pribut N; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Sharma SK; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., D'Erasmo MP; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Bartsch PW; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Sun C; Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, United States., Toti K; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States., Arnold RS; Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, United States.; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, United States., Petros JA; Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, United States.; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, United States., Xu L; Junrui Biotechnology, Hangzhou, Zhejiang 310000, China., Jiang Y; Junrui Biotechnology, Hangzhou, Zhejiang 310000, China., Miller EJ; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, United States.; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, United States., Liotta DC; Department of Chemistry, Emory University College of Arts and Sciences, Atlanta, Georgia 30322, United States.; Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, United States.

Publikováno v: ACS pharmacology & translational science [ACS Pharmacol Transl Sci] 2023 Feb 23; Vol. 6 (5), pp. 702-709. Date of Electronic Publication: 2023 Feb 23 (Print Publication: 2023).