Polycyclic aromatic hydrocarbon skin permeation efficiency in vitro is lower through human than pigskin and decreases with lipophilicity.

Autor: Simon K; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany; Department of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2-4, 14195, Berlin, Germany. Electronic address: Konstantin.Simon@bfr.bund.de., Bartsch N; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany; German Federal Office of Consumer Protection and Food Safety, Bundesallee 51, 38116, Braunschweig, Germany., Schneider L; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany., van de Weijgert V; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products, Antonie van Leeuwenhoeklaan 9, 3721, MA Bilthoven, Netherlands., Hutzler C; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany., Luch A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany; Department of Biology, Chemistry, Pharmacy, Institute of Pharmacy, Freie Universität Berlin, Königin-Luise-Str. 2-4, 14195, Berlin, Germany., Roloff A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany. Electronic address: Alexander.Roloff@bfr.bund.de.

Publikováno v: Environmental research [Environ Res] 2024 Aug 15; Vol. 255, pp. 119118. Date of Electronic Publication: 2024 May 17.

CAR T-cell therapy rescues adolescent with rapidly progressive lupus nephritis from haemodialysis.

Autor: Krickau T; Department of Paediatrics and Adolescent Medicine, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany., Naumann-Bartsch N; Department of Paediatrics and Adolescent Medicine, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Aigner M; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany., Kharboutli S; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Kretschmann S; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Spoerl S; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany., Vasova I; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Völkl S; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Woelfle J; Department of Paediatrics and Adolescent Medicine, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany., Mackensen A; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany., Schett G; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Department of Internal Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany., Metzler M; Department of Paediatrics and Adolescent Medicine, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany. Electronic address: markus.metzler@uk-erlangen.de., Müller F; Deutsches Zentrum Immuntherapie, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Department of Internal Medicine 5, Haematology and Oncology, Universitätsklinikum Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen 91054, Germany; Bavarian Cancer Research Center (BZKF), partner site Erlangen, Germany.

Publikováno v: Lancet (London, England) [Lancet] 2024 Apr 27; Vol. 403 (10437), pp. 1627-1630. Date of Electronic Publication: 2024 Apr 17.

Survival in primary hemophagocytic lymphohistiocytosis, 2016 to 2021: etoposide is better than its reputation.

Autor: Böhm S; Division of Pediatric Stem Cell Transplantation and Immunology, University Medical Center Eppendorf, Hamburg, Germany., Wustrau K; Division of Pediatric Stem Cell Transplantation and Immunology, University Medical Center Eppendorf, Hamburg, Germany.; Department of Pediatrics, University Medical Center Ulm, Ulm, Germany., Pachlopnik Schmid J; Division of Immunology and Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland.; Pediatric Immunology, University Children's Hospital Zurich-Eleonorenstiftung, Zürich, Switzerland., Prader S; Division of Immunology and Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland.; Pediatric Immunology, University Children's Hospital Zurich-Eleonorenstiftung, Zürich, Switzerland., Ahlmann M; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany., Yacobovich J; Schneider Children's Medical Center of Israel, Petah Tikva, Israel.; Tel Aviv Medical School, Tel Aviv University, Tel Aviv, Israel., Beier R; Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany., Speckmann C; Division of Pediatric Hematology and Oncology Faculty of Medicine, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany.; Center for Chronic Immunodeficiency, Institute for Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Behnisch W; Center for Pediatrics and Adolescent Medicine, Hematology/Oncology, Heidelberg University Hospital, Heidelberg, Germany., Ifversen M; Department of Pediatrics and Adolescent Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Jordan M; Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Marsh R; Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, OH., Naumann-Bartsch N; Clinic for Children and Adolescents, University Clinic Erlangen, Erlangen, Germany., Mauz-Körholz C; Pediatric Hematooncology, University Children's Hospital Giessen, Giessen, Germany.; Medical Faculty, Martin-Luther University of Halle-Wittenberg, Halle, Germany., Hönig M; Department of Pediatrics, University Medical Center Ulm, Ulm, Germany., Schulz A; Department of Pediatrics, University Medical Center Ulm, Ulm, Germany., Malinowska I; Department of Oncology, Pediatric Hematology, Clinical Transplantology and Pediatrics, Medical University of Warsaw, Warsaw, Poland., Hines M; Division of Critical Care, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN., Nichols KE; Division of Critical Care, Department of Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN., Gil-Herrera J; Immunology, Hospital General Universitario and Instituto de Investigación Sanitaria 'Gregorio Marañón,' Madrid, Spain., Talano JA; Pediatric Hematology/Oncology/Blood and Marrow Transplant Division, Medical College of Wisconsin, Madison, WI., Crooks B; Paediatric Haematology/Oncology, IWK Health Centre, Halifax, NS, Canada., Formankova R; Department of Pediatric Haematology and Oncology, University Hospital Motol Prague, Prague, Czech Republic., Jorch N; Bielefeld University, University Clinic for Pediatrics, Evangelisches Klinikum Bethel, Bielefeld, Germany., Bakhtiar S; Center for Pediatric and Adolescent Medicine, Frankfurt University Hospital, Frankfurt, Germany., Kühnle I; Division of Pediatric Hematology and Oncology, Göttingen University Medical Center, Göttingen, Germany., Streiter M; Clinic for Pediatrics and Adolescent Medicine, Hematology/Oncology, Klinikum am Gesundbrunnen Heilbronn, Heilbronn, Germany., Nathrath M; Pediatric Hematology and Oncology, Psychosomatics and Systemic Diseases, Kassel Hospital, Kassel, Germany.; Department of Pediatrics and Children's Cancer Research Center, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany., Russo A; Center for Pediatric and Adolescent Medicine, Pediatric Hematology/Oncology, University of Mainz, Mainz, Germany., Dürken M; Department of Pediatrics and Adolescent Medicine, Mannheim University Hospital, Mannheim, Germany., Lang P; Clinic for Children and Adolescents, Department I Hematology/Oncology, Tübingen University Hospital, Tübingen, Germany., Lindemans C; Department of Pediatrics, University Medical Center Utrecht, Utrecht, The Netherlands.; Princess Máxima Center, Utrecht, The Netherlands., Henter JI; Department of Women's and Children's Health, Childhood Cancer Research Unit, Karolinska Institutet, Stockholm, Sweden.; Theme of Children's Health, Karolinska University Hospital, Stockholm, Sweden., Lehmberg K; Division of Pediatric Stem Cell Transplantation and Immunology, University Medical Center Eppendorf, Hamburg, Germany., Ehl S; Center for Chronic Immunodeficiency, Institute for Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Publikováno v: Blood [Blood] 2024 Mar 07; Vol. 143 (10), pp. 872-881.

NvPrdm14d-expressing neural progenitor cells contribute to non-ectodermal neurogenesis in Nematostella vectensis.

Autor: Lemaître QIB; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Bartsch N; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway.; Department for Biological Sciences, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Kouzel IU; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Busengdal H; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Richards GS; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Steinmetz PRH; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway., Rentzsch F; Michael Sars Centre, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway. fabian.rentzsch@uib.no.; Department for Biological Sciences, University of Bergen, Thormøhlensgate 55, 5006, Bergen, Norway. fabian.rentzsch@uib.no.

Publikováno v: Nature communications [Nat Commun] 2023 Aug 10; Vol. 14 (1), pp. 4854. Date of Electronic Publication: 2023 Aug 10.

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia.

Autor: García-García A; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain., Pérez de Diego R; Laboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz Hospital , Madrid, Spain., Flores C; Genomics Division, Instituto Tecnológico y de Energías Renovables , Santa Cruz de Tenerife, Spain.; Research Unit, Hospital Universitario N.S. de Candelaria , Santa Cruz de Tenerife, Spain.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain., Rinchai D; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA., Solé-Violán J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III , Madrid, Spain.; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain.; Dept. of Intensive Care Medicine, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Deyà-Martínez À; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain., García-Solis B; Laboratory of Immunogenetics of Human Diseases, IdiPAZ Institute for Health Research, La Paz Hospital , Madrid, Spain., Lorenzo-Salazar JM; Genomics Division, Instituto Tecnológico y de Energías Renovables , Santa Cruz de Tenerife, Spain., Hernández-Brito E; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Lanz AL; Dept. of Pediatrics, Division of Pediatric Immunology and Rheumatology, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München , Munich, Germany., Moens L; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium., Bucciol G; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium.; Dept. of Pediatrics, Childhood Immunology, UZ Leuven , Leuven, Belgium., Almuqamam M; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Domachowske JB; Dept. of Pediatrics, SUNY Upstate Medical University , Syracuse, NY, USA., Colino E; Unidad de Enfermedades Infecciosas, Complejo Hospitalario Universitario Insular-Materno Infantil , Las Palmas de Gran Canaria, Spain., Santos-Perez JL; Unidad de Gestión Clínica de Pediatría y Cirugía Pediátrica, Hospital Virgen de las Nieves-IBS , Granada, Spain., Marco FM; Dept. of Immunology, Alicante University General Hospital Doctor Balmis , Alicante, Spain.; Alicante Institute for Health and Biomedical Research , Alicante, Spain., Pignata C; Dept. of Translational Medical Sciences, Section of Pediatrics, Federico II University , Naples, Italy., Bousfiha A; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Turvey SE; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Bauer S; Clinic for Children and Adolescents. Dept. of Hematology and Oncology. University Clinic Erlangen , Erlangen, Germany., Haerynck F; Dept. of Pediatric Immunology and Pulmonology, Centre for Primary Immune Deficiency Ghent, Ghent University Hospital , Ghent, Belgium.; Dept. of Internal Medicine and Pediatrics, PID Research Laboratory, Ghent University , Ghent, Belgium., Ocejo-Vinyals JG; Dept. of Immunology, University Hospital Marqués de Valdecilla, IDIVAL , Santander, Spain., Lendinez F; Dept. of Pediatric Oncohematology, Hospital Materno Infantil Torrecárdenas , Almería, Spain., Prader S; Division of Immunology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; University of Zurich , Zurich, Switzerland., Naumann-Bartsch N; Clinic for Children and Adolescents. Dept. of Hematology and Oncology. University Clinic Erlangen , Erlangen, Germany., Pachlopnik Schmid J; Division of Immunology and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; University of Zurich , Zurich, Switzerland., Biggs CM; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Hildebrand K; Dept. of Paediatrics, BC Children's Hospital, University of British Columbia , Vancouver, Canada., Dreesman A; Dept. of Pediatrics, CHU St Pierre, ULB/VUB , Brussels, Belgium., Cárdenes MÁ; Dept. of Internal Medicine, Unit of Infectious Diseases, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Ailal F; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Benhsaien I; Dept. of Pediatric Infectious Diseases and Clinical Immunology, Ibn Rushd University Hospital , Casablanca, Morocco.; Clinical Immunology, Autoimmunity and Inflammation Laboratory, Faculty of Medicine and Pharmacy, Hassan II University , Casablanca, Morocco., Giardino G; Dept. of Translational Medical Sciences, Section of Pediatrics, Federico II University , Naples, Italy., Molina-Fuentes A; Dept. of Immunology, UGC Laboratories, University Hospital of Jaén , Jaén, Spain., Fortuny C; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Pediatric Infectious Diseases Unit, Hospital Sant Joan de Déu , Barcelona, Spain.; CIBER of Epidemiology and Public Health, Madrid, Spain; Translational Research Network in Pediatric Infectious Diseases , Madrid, Spain.; Dept. of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, University of Barcelona , Barcelona, Spain., Madhavarapu S; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Conway DH; Dept. of Pediatrics, Drexel University College of Medicine, St Christopher's Hospital for Children , Philadelphia, PA, USA., Prando C; Instituto de Pesquisa Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Hospital Pequeno Príncipe , Curitiba, Brazil., Schidlowski L; Instituto de Pesquisa Pelé Pequeno Príncipe, Faculdades Pequeno Príncipe, Hospital Pequeno Príncipe , Curitiba, Brazil., Martínez de Saavedra Álvarez MT; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Alfaro R; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Rodríguez de Castro F; Dept. of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria , Las Palmas de Gran Canaria, Spain.; Dept. of Respiratory Diseases, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain., Meyts I; Laboratory for Inborn Errors of Immunity, Dept. of Microbiology, Immunology and Transplantation KU Leuven , Leuven, Belgium.; Dept. of Pediatrics, Childhood Immunology, UZ Leuven , Leuven, Belgium., Hauck F; Dept. of Pediatrics, Division of Pediatric Immunology and Rheumatology, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München , Munich, Germany., Puel A; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Bastard P; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; Pediatric Hematology and Immunology Unit, Department of Pediatrics, Necker Hospital for Sick Children, AP-HP , Paris, France., Boisson B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Jouanguy E; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Abel L; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Zhang Q; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France., Casanova JL; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University , New York, NY, USA.; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children , Paris, France.; University Paris Cité, Imagine Institute , Paris, France.; Department of Pediatrics, Necker Hospital for Sick Children , Paris, France.; Howard Hughes Medical Institute , New York, NY, USA., Alsina L; Pediatric Allergy and Clinical Immunology Dept., Clinical Immunology and Primary Immunodeficiencies Unit, Hospital Sant Joan de Déu, Barcelona , Barcelona, Spain.; Study Group for Immune Dysfunction Diseases in Children, Institut de Recerca Sant Joan de Déu, Barcelona , Barcelona, Spain.; Clinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona , Barcelona, Spain.; Dept. of Surgery and Surgical Specializations, Facultat de Medicina i Ciències de la Salut, University of Barcelona , Barcelona, Spain., Rodríguez-Gallego C; Dept. of Clinical Sciences, University Fernando Pessoa Canarias , Las Palmas de Gran Canaria, Spain.; Dept. of Immunology, University Hospital of Gran Canaria Dr. Negrin, Canarian Health System , Las Palmas de Gran Canaria, Spain.; Dept. of Medical and Surgical Sciences, School of Medicine, University of Las Palmas de Gran Canaria , Las Palmas de Gran Canaria, Spain.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2023 May 01; Vol. 220 (5). Date of Electronic Publication: 2023 Mar 03.