Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Barton E. Slatko"'
Autor:
Christina A. Bulman, Laura Chappell, Emma Gunderson, Ian Vogel, Brenda Beerntsen, Barton E. Slatko, William Sullivan, Judy A. Sakanari
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-13 (2021)
Abstract Background Onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) are two human neglected tropical diseases that cause major disabilities. Mass administration of drugs targeting the microfilarial stage has reduced transmis
Externí odkaz:
https://doaj.org/article/0611375bb2534445ade0809a7e229283
Autor:
Matthew Chung, Preston J. Basting, Rayanna S. Patkus, Alexandra Grote, Ashley N. Luck, Elodie Ghedin, Barton E. Slatko, Michelle Michalski, Jeremy M. Foster, Casey M. Bergman, Julie C. Dunning Hotopp
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3243-3260 (2020)
Wolbachia is a genus containing obligate, intracellular endosymbionts with arthropod and nematode hosts. Numerous studies have identified differentially expressed transcripts in Wolbachia endosymbionts that potentially inform the biological interplay
Externí odkaz:
https://doaj.org/article/3e5d92a74bcd4481a9a2646cc7012433
Autor:
Emilie Lefoulon, Travis Clark, Fanni Borveto, Marco Perriat-Sanguinet, Catherine Moulia, Barton E. Slatko, Laurent Gavotte
Publikováno v:
BMC Microbiology, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background Wolbachia are the most widely spread endosymbiotic bacteria, present in a wide variety of insects and two families of nematodes. As of now, however, relatively little genomic data has been available. The Wolbachia symbiont can be
Externí odkaz:
https://doaj.org/article/7bb21211aff54df3ba518eff19280980
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 2 (2021)
ABSTRACT Endosymbiotic Wolbachia bacteria are known to influence the host physiology, microbiota composition, and dissemination of pathogens. We surveyed a population of Tabanus nigrovittatus, commonly referred to as “greenheads,” from Crane Beac
Externí odkaz:
https://doaj.org/article/22d6e1ba222543fcb3cf5c8124abf6cb
Autor:
Rachel H. Clare, Catherine Bardelle, Paul Harper, W. David Hong, Ulf Börjesson, Kelly L. Johnston, Matthew Collier, Laura Myhill, Andrew Cassidy, Darren Plant, Helen Plant, Roger Clark, Darren A. N. Cook, Andrew Steven, John Archer, Paul McGillan, Sitthivut Charoensutthivarakul, Jaclyn Bibby, Raman Sharma, Gemma L. Nixon, Barton E. Slatko, Lindsey Cantin, Bo Wu, Joseph Turner, Louise Ford, Kirsty Rich, Mark Wigglesworth, Neil G. Berry, Paul M. O’Neill, Mark J. Taylor, Stephen A. Ward
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Parasitic nematodes causing onchocerciasis and lymphatic filariasis rely on a bacterial endosymbiont, Wolbachia, which is a validated therapeutic target. Here, Clare et al. perform a high-throughput screen of 1.3 million compounds and identify 5 chem
Externí odkaz:
https://doaj.org/article/4cb4bba947a8460babf1f27b9cb22a73
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Lateral gene transfer (LGT) from microbial symbionts to invertebrate animals is described at an increasing rate, particularly between Wolbachia endosymbionts and their diverse invertebrate hosts. We sought to assess the use of a capture syst
Externí odkaz:
https://doaj.org/article/615865d84e6d43a0b823249be7faf09c
Autor:
Rama K. Simhadri, Eva M. Fast, Rong Guo, Michaela J. Schultz, Natalie Vaisman, Luis Ortiz, Joanna Bybee, Barton E. Slatko, Horacio M. Frydman
Publikováno v:
mSphere, Vol 2, Iss 5 (2017)
ABSTRACT Endosymbiotic Wolbachia bacteria and the gut microbiome have independently been shown to affect several aspects of insect biology, including reproduction, development, life span, stem cell activity, and resistance to human pathogens, in inse
Externí odkaz:
https://doaj.org/article/e5a766ae78bf4e3db960a9172d154811
Autor:
Michael P. Weiner, Barton E. Slatko
Publikováno v:
BioTechniques, Vol 44, Iss 5, Pp 701-704 (2008)
An innovation is one of those things that society looks at and says, if we make this part of the way we live and work, it will change the way we live and work. —Dean Kamen One of my primary objects is to form the tools so the tools themselves shall
Externí odkaz:
https://doaj.org/article/6665212b907043deb2b9c7f54fcb6dd8
Autor:
Rayanna S. Patkus, Ashley N. Luck, Matthew Chung, Preston J. Basting, Barton E. Slatko, Jeremy M. Foster, Alexandra Grote, Casey M. Bergman, Michelle L. Michalski, Elodie Ghedin, Julie C. Dunning Hotopp
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 9, Pp 3243-3260 (2020)
Wolbachia is a genus containing obligate, intracellular endosymbionts with arthropod and nematode hosts. Numerous studies have identified differentially expressed transcripts in Wolbachia endosymbionts that potentially inform the biological interplay
Autor:
Helen Plant, Kirsty Rich, Darren Plant, Paul Harper, Catherine Bardelle, Louise Ford, Eileen McCall, Barton E. Slatko, Lindsey J. Cantin, Matthew Collier, Bo Wu, Mark J. Taylor, Mark Wigglesworth, Stephen A. Ward, Kelly L. Johnston, David Murray, Rachel H. Clare, Roger Clark
Publikováno v:
Slas Discovery
The Anti- Wolbachia (A·WOL) consortium at the Liverpool School of Tropical Medicine (LSTM) has partnered with the Global High-Throughput Screening (HTS) Centre at AstraZeneca to create the first anthelmintic HTS for neglected tropical diseases (NTDs