Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Bartolomeus J Meijer"'
Autor:
Evelien Dekker, Lianne Koens, Barbara A J Bastiaansen, Victorine H Roos, Bartolomeus J Meijer, Frank G J Kallenberg, Frederike J Bemelman, Patrick M M Bossuyt, Jarom Heijmans, Gijs van den Brink
Publikováno v:
BMJ Open Gastroenterology, Vol 7, Iss 1 (2020)
Objective After prophylactic colectomy, adenomas continue to develop in the remaining intestine of patients with familial adenomatous polyposis (FAP). There is a lack of standard clinical recommendation for chemoprevention in patients with FAP. Becau
Externí odkaz:
https://doaj.org/article/4ed12c2c41c74e5ab353a647b9f04bf6
Autor:
Bartolomeus J. Meijer, Francesca P. Giugliano, Bart Baan, Jonathan H.M. van der Meer, Sander Meisner, Manon van Roest, Pim J. Koelink, Ruben J. de Boer, Nic Jones, Wolfgang Breitwieser, Nicole N. van der Wel, Manon E. Wildenberg, Gijs R. van den Brink, Jarom Heijmans, Vanesa Muncan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Background & Aims: Activation factor-1 transcription factor family members activating transcription factors 2 and 7 (ATF2 and ATF7) have highly redundant functions owing to highly homologous DNA binding sites. Their role in intestinal epithelial home
Externí odkaz:
https://doaj.org/article/5ca26a8b84574534a05a42331734351c
Autor:
Jarom Heijmans, Vanesa Muncan, Gijs R. van den Brink, Manon E. Wildenberg, Jacqueline L.M. Vermeulen, Sander Meisner, Amy S. Lee, B. Florien Westendorp, Mattheus C.B. Wielenga, Tanya T.D. Soeratram, Wouter L. Smit, Bartolomeus J. Meijer, Claudia N. Spaan, Jooske F. van Lidth de Jeude
Supplementary Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cf0e9baa03388dd54994e3a8686233
https://doi.org/10.1158/0008-5472.22420026.v1
https://doi.org/10.1158/0008-5472.22420026.v1
Autor:
Jarom Heijmans, Vanesa Muncan, Gijs R. van den Brink, Manon E. Wildenberg, Jacqueline L.M. Vermeulen, Sander Meisner, Amy S. Lee, B. Florien Westendorp, Mattheus C.B. Wielenga, Tanya T.D. Soeratram, Wouter L. Smit, Bartolomeus J. Meijer, Claudia N. Spaan, Jooske F. van Lidth de Jeude
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f03fc49019fb84665dbbcafb1c8880f
https://doi.org/10.1158/0008-5472.22420011.v1
https://doi.org/10.1158/0008-5472.22420011.v1
Autor:
Jarom Heijmans, Vanesa Muncan, Gijs R. van den Brink, Manon E. Wildenberg, Jacqueline L.M. Vermeulen, Sander Meisner, Amy S. Lee, B. Florien Westendorp, Mattheus C.B. Wielenga, Tanya T.D. Soeratram, Wouter L. Smit, Bartolomeus J. Meijer, Claudia N. Spaan, Jooske F. van Lidth de Jeude
Deletion of endoplasmic reticulum resident chaperone Grp78 results in activation of the unfolded protein response and causes rapid depletion of the entire intestinal epithelium. Whether modest reduction of Grp78 may affect stem cell fate without comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb3f0dd3e995dfde2fe451236d8801ba
https://doi.org/10.1158/0008-5472.c.6510534.v1
https://doi.org/10.1158/0008-5472.c.6510534.v1
Autor:
Sander Meisner, Nic Jones, Pim J. Koelink, Wolfgang Breitwieser, Nicole N. van der Wel, F.P. Giugliano, Bart Baan, Bartolomeus J. Meijer, Ruben J. de Boer, Manon van Roest, Vanesa Muncan, Gijs R. van den Brink, Jarom Heijmans, Jonathan H. M. van der Meer, Manon E. Wildenberg
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, 10(1), 23-42. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Cellular and molecular gastroenterology and hepatology, 10(1), 23-42. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 23-42 (2020)
Background & Aims Activation factor-1 transcription factor family members activating transcription factors 2 and 7 (ATF2 and ATF7) have highly redundant functions owing to highly homologous DNA binding sites. Their role in intestinal epithelial homeo
Autor:
Pim J. Koelink, James C. Paton, Jonathan H. M. van der Meer, Wouter L. Smit, Gijs R. van den Brink, Ruben J. de Boer, Bartolomeus J. Meijer, Adrienne W. Paton, Jarom Heijmans, Jacqueline L.M. Vermeulen, Vanesa Muncan, Barbara F. Westendorp, Jun Qin, Evelien Dekker
Publikováno v:
Scientific reports, 11(1):9892. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Enforcing differentiation of cancer stem cells is considered as a potential strategy to sensitize colorectal cancer cells to irradiation and chemotherapy. Activation of the unfolded protein response, due to endoplasmic reticulum (ER) stress, causes r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224046a787934079d32021515ba0fffd
http://www.scopus.com/inward/record.url?scp=85105583312&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85105583312&partnerID=8YFLogxK
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis
Autor:
Evelien Dekker, Bartolomeus J. Meijer, Ruben J. de Boer, Manon van Roest, Pim J. Koelink, Lukas J. A. C. Hawinkels, Jonathan H. M. van der Meer, Sander Meisner, Vanesa Muncan, Theodorus B. M. Hakvoort, Wouter L. Smit, Gijs R. van den Brink, Jan Koster, Jarom Heijmans, Marja A. Boermeester, Eduard A. Struijs, Jacqueline L.M. Vermeulen
Publikováno v:
Cell death & disease, 12(10):897. Nature Publishing Group
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death and Disease, 12(10). SPRINGERNATURE
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Cell Death & Disease
Cell Death and Disease, 12(10). SPRINGERNATURE
The epithelial signaling pathways involved in damage and regeneration, and neoplastic transformation are known to be similar. We noted upregulation of argininosuccinate synthetase (ASS1) in hyperproliferative intestinal epithelium. Since ASS1 leads t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fe9f6b68e63ef2adef8188598cf44c
https://pure.amc.nl/en/publications/epithelial-argininosuccinate-synthetase-is-dispensable-for-intestinal-regeneration-and-tumorigenesis(b6498dad-bf3b-4e68-8c11-ffc21c53a4e0).html
https://pure.amc.nl/en/publications/epithelial-argininosuccinate-synthetase-is-dispensable-for-intestinal-regeneration-and-tumorigenesis(b6498dad-bf3b-4e68-8c11-ffc21c53a4e0).html
Autor:
G. R. van den Brink, Wouter L. Smit, M. S. Van Der Knaap, Jan Koster, Jarom Heijmans, M. van Roest, Pim J. Koelink, Evelien Dekker, Claudia N. Spaan, Bartolomeus J. Meijer, R.J. de Boer, Vanesa Muncan, Truus E.M. Abbink
Publikováno v:
Stem cell research, 55:102499. Elsevier
Smit, W L, de Boer, R J, Meijer, B J, Spaan, C N, van Roest, M, Koelink, P J, Koster, J, Dekker, E, Abbink, T E M, van der Knaap, M S, van den Brink, G R, Muncan, V & Heijmans, J 2021, ' Translation initiation factor eIF2Bε promotes Wnt-mediated clonogenicity and global translation in intestinal epithelial cells ', Stem Cell Research, vol. 55, 102499 . https://doi.org/10.1016/j.scr.2021.102499
Stem Cell Research, Vol 55, Iss, Pp 102499-(2021)
Stem Cell Research, 55:102499. Elsevier
Smit, W L, de Boer, R J, Meijer, B J, Spaan, C N, van Roest, M, Koelink, P J, Koster, J, Dekker, E, Abbink, T E M, van der Knaap, M S, van den Brink, G R, Muncan, V & Heijmans, J 2021, ' Translation initiation factor eIF2Bε promotes Wnt-mediated clonogenicity and global translation in intestinal epithelial cells ', Stem Cell Research, vol. 55, 102499 . https://doi.org/10.1016/j.scr.2021.102499
Stem Cell Research, Vol 55, Iss, Pp 102499-(2021)
Stem Cell Research, 55:102499. Elsevier
Modulation of global mRNA translation, which is essential for intestinal stem cell function, is controlled by Wnt signaling. Loss of tumor supressor APC in stem cells drives adenoma formation through hyperactivion of Wnt signaling and dysregulated tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5df3b40aac6c8d011bc0f5ef896af5
https://pure.amc.nl/en/publications/translation-initiation-factor-eif2b-promotes-wntmediated-clonogenicity-and-global-translation-in-intestinal-epithelial-cells(493d7dc5-9adf-4b47-8bd5-ecbf0bd6455a).html
https://pure.amc.nl/en/publications/translation-initiation-factor-eif2b-promotes-wntmediated-clonogenicity-and-global-translation-in-intestinal-epithelial-cells(493d7dc5-9adf-4b47-8bd5-ecbf0bd6455a).html
Autor:
Claudia N. Spaan, Jarom Heijmans, Jan Koster, Ruben J. de Boer, Alyson W. MacInnes, Jacqueline Ludovicus Maria Vermeulen, Wouter L. Smit, Gijs R. van den Brink, Tânia Martins Garcia, Jan Paul Medema, Marco Lezzerini, Vanesa Muncan, Prashanthi Ramesh, Bartolomeus J. Meijer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 117(41), 25560-25570. National Academy of Sciences
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Deregulated global mRNA translation is an emerging feature of cancer cells. Oncogenic transformation in colorectal cancer (CRC) is driven by mutations in APC, KRAS, SMAD4, and TP53, known as the adenoma-carcinoma sequence (ACS). Here we introduce eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc285b42dbd5905f7bee76ae706c536
https://pure.amc.nl/en/publications/driver-mutations-of-the-adenomacarcinoma-sequence-govern-the-intestinal-epithelial-global-translational-capacity(b9887a9c-b0c1-49aa-bfe1-d01c5e5c2282).html
https://pure.amc.nl/en/publications/driver-mutations-of-the-adenomacarcinoma-sequence-govern-the-intestinal-epithelial-global-translational-capacity(b9887a9c-b0c1-49aa-bfe1-d01c5e5c2282).html