Pancreatic cancer cells overexpressing interleukin 6 induce T-cell-mediated tumor clearance and durable anti-tumor immune response.

Autor: Arneson-Wissink PC; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., Bartlett AQ; Division of Surgical Oncology, Department of Surgery, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA., Mendez H; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., Zhu X; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., Dickie J; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., McWhorter M; Division of Surgical Oncology, Department of Surgery, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA., Levasseur PR; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., Diba P; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA., Byrne KT; Department of Cell, Development, and Cancer Biology, Oregon Health & Science University,Portland, OR, 97239, USA.; Brenden Colson Center for Pancreatic Care, Oregon Health & Science University, Portland,OR, 97239, USA., Scott GD; Department of Pathology, Oregon Health & Science University, Portland, OR, 97239, USA., Eil R; Division of Surgical Oncology, Department of Surgery, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, 97239, USA., Grossberg AJ; Department of Radiation Medicine, Oregon Health & Science University, Portland, OR, 97239, USA.; Brenden Colson Center for Pancreatic Care, Oregon Health & Science University, Portland,OR, 97239, USA.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University,Portland, OR, 97201, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 27. Date of Electronic Publication: 2024 Sep 27.

Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes.

Autor: Jindal S; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Pennock ND; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA., Sun D; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA., Horton W; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA.; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA., Ozaki MK; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA., Narasimhan J; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA., Bartlett AQ; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA., Weinmann S; Center for Health Research, Kaiser Permanente Northwest, 3800N. Interstate Ave., Portland, OR, USA., Goss PE; Massachusetts General Hospital Cancer Center, Harvard University, Boston, MA, USA., Borges VF; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Young Women's Breast Cancer Translational Program, University of Colorado Cancer Center, Aurora, CO, USA., Xia Z; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Computational Biology Program, Oregon Health & Science University, Portland, OR, USA.; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA., Schedin P; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, OR, USA. schedin@ohsu.edu.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. schedin@ohsu.edu.; Young Women's Breast Cancer Translational Program, University of Colorado Cancer Center, Aurora, CO, USA. schedin@ohsu.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Nov 03; Vol. 12 (1), pp. 6341. Date of Electronic Publication: 2021 Nov 03.